ZLAB — Zai Lab Ltd

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates ZLAB Bearish with a Setup Score of 54, net conviction 57, actionability 52. How the Setup Score works →

Total Setup Score54
Directional BiasBearish
Net Conviction57
Actionability52 (in range)

Key signals behind this score

About Zai Lab Ltd

Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases. Its commercial products include Zejula, an orally administered poly (ADP-ribose) polymerase 1/2 inhibitor for treating ovarian cancer; VYVGART, a human IgG1 antibody fragment for generalized myasthenia gravis and chronic inflammat… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$20.49
Market Cap$2.25B
Float91.7M
Shares Outstanding112.9M
Price/Sales (TTM)4.96
vs. Analyst Target+62.5% to analyst PT
Profit Margin-39.29%
Operating Margin (TTM)-69.66%
Revenue (TTM)$453M
Dividend RateNone
Analyst Target Price$33.30 (12 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $49.0M -$269M -$190M -$297M
2021 $144M -$704M $92.1M -$689M
2022 $215M -$443M $141M -$435M
2023 $267M -$335M $171M -$365M
2024 $399M -$257M $251M -$235M
2025 $460M -$176M $269M -$158M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $110M -$40.7M
Sep 2025 $116M -$36.0M
Dec 2025 $128M -$50.4M
Mar 2026 $99.6M -$51.0M

Ownership & Float

Insider Ownership2.2%
Institutional Ownership31.3%
Short Float7.9%
% of All Funds Holding1.08%
Number of Funds Holding89

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$18.50Near-term / short-term trend
Weekly40-Week SMA$20.10Medium-term trend
Weekly80-Week SMA$26.33Cyclical trend (business cycle)
Weekly200-Week SMA$26.83Secular trend (multi-year)
Monthly10-Month SMA$19.76Near-term monthly trend
Monthly20-Month SMA$26.17Medium-term monthly trend
Monthly40-Month SMA$25.25Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$38.20 resistance 1.85x 14 months ago
$15.90 support 1.52x 25 months ago

Historical Earnings Reactions (35 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 1.17% -0.21% 45.71% 21.00% -9.19%
1 Day -1.10% -1.06% 42.86% 26.80% -10.86%
1 Week -0.42% -0.76% 48.57% 31.52% -25.75%
2 Weeks 0.04% -1.07% 48.57% 26.98% -31.86%
1 Month 2.19% -0.09% 50.00% 42.07% -25.66%

Next earnings: August 6, 2026 (24 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan8.6%66.7%9
Feb3.1%55.6%9
Mar-7.6%22.2%9
Apr2.4%44.4%9
May0.5%44.4%9
Jun7.5%55.6%9
Jul0.5%50.0%8
Aug0.1%62.5%8
Sep-5.6%37.5%8
Oct-4.7%44.4%9
Nov10.1%55.6%9
Dec-2.9%44.4%9

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.08% 49.0% 414
Tuesday 0.25% 51.4% 455
Wednesday 0.24% 51.0% 451
Thursday -0.26% 45.9% 444
Friday 0.21% 49.0% 443

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 31.3%

Insider Transactions — Smart Summary

Total insider ownership: 2.2%

Founder-led management: Samantha Du (Founder, Chairperson & CEO)

12-Month Insider Activity Summary

Total Filings42
Net Value-$18.9M
Net Shares Change268,129
% of Float0.3%
C-Suite Filings39
Clusters Detected4

Key Insiders

NameTitleNet ValueFilingsActivity
Du Ying Chairperson & CEO -$558,765.207 2 2 sell
Amado Rafael President, Head of Global Oncology Research and Development -$202,064.9 1 1 sell
Edmondson Frazor Titus III Chief Legal Officer -$181,020.611 3 3 sell
Chen Yajing Chief Financial Officer -$145,539.314 2 2 sell
Smiley Joshua L President and Chief Operating Officer +$93,070.54 2 1 buy, 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-12 – 2025-08-19 7 5 -$7.3M 7 C-suite
2026-03-05 – 2026-03-19 10 6 -$5.9M 9 C-suite
2026-04-03 – 2026-04-08 10 5 -$917,729.998 10 C-suite
2026-06-24 – 2026-07-06 6 5 -$764,222.194 4 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-06-29 Edmondson Frazor Titus III Chief Legal Officer -$71,642.483 Transaction at $17.46, now +17.3%
2026-06-29 Chen Yajing Chief Financial Officer -$39,531.704 Transaction at $17.46, now +17.3%
2026-06-29 Du Ying Chairperson & CEO -$428,545.323 Transaction at $17.46, now +17.3%
2026-07-01 Du Ying Chairperson & CEO -$130,219.884 Transaction at $18.53, now +10.6%
2025-09-12 Smiley Joshua L President and Chief Operating Officer +$289,100 Transaction at $28.91, now -29.1%
2026-04-03 Smiley Joshua L President and Chief Operating Officer -$196,029.46 Transaction at $20.39, now +0.5%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Zai Lab Ltd (ZLAB) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ZLAB on Trend Edge →