Stock analysis, trade plans, and proprietary indicators by Trend Edge.
About Zai Lab Ltd
Zai Lab Limited, a biopharmaceutical company, focuses on discovering, developing, and commercializing products that address medical conditions in the areas of oncology, immunology, neuroscience, and infectious diseases. Its commercial products include Zejula, an orally administered poly (ADP-ribose) polymerase 1/2 inhibitor for treating ovarian cancer; VYVGART, a human IgG1 antibody fragment for generalized myasthenia gravis and chronic inflammat… Read full Trend Edge analysis →
Founder-Led: Yes — Samantha Du (Founder, Chairperson & CEO)
Key Metrics
Current Price
$18.69
Market Cap
$2.10B
Float
979.1M
Shares Outstanding
112.4M
Price/Sales (TTM)
4.64
vs. Analyst Target
+80.7% to analyst PT
Profit Margin
-39.29%
Operating Margin (TTM)
-69.66%
Revenue (TTM)
$453M
Dividend Rate
None
Analyst Target Price
$33.78 (12 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$49.0M
-$269M
-$190M
-$297M
2021
$144M
-$704M
$92.1M
-$689M
2022
$215M
-$443M
$141M
-$435M
2023
$267M
-$335M
$171M
-$365M
2024
$399M
-$257M
$251M
-$235M
2025
$460M
-$176M
$269M
-$158M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$110M
-$40.7M
Sep 2025
$116M
-$36.0M
Dec 2025
$128M
-$50.4M
Mar 2026
$99.6M
-$51.0M
Ownership & Float
Insider Ownership
2.0%
Institutional Ownership
29.2%
Short Float
0.5%
% of All Funds Holding
1.08%
Number of Funds Holding
89
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$20.41
Near-term / short-term trend
Weekly
40-Week SMA
$22.25
Medium-term trend
Weekly
80-Week SMA
$27.01
Cyclical trend (business cycle)
Weekly
200-Week SMA
$27.66
Secular trend (multi-year)
Monthly
10-Month SMA
$22.61
Near-term monthly trend
Monthly
20-Month SMA
$27.20
Medium-term monthly trend
Monthly
40-Month SMA
$26.05
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$38.20
resistance
1.85x
12 months ago
$15.90
support
1.52x
23 months ago
Historical Earnings Reactions (35 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
1.17%
-0.21%
45.71%
21.00%
-9.19%
1 Day
-1.10%
-1.06%
42.86%
26.80%
-10.86%
1 Week
-0.42%
-0.76%
48.57%
31.52%
-25.75%
2 Weeks
0.04%
-1.07%
48.57%
26.98%
-31.86%
1 Month
2.19%
-0.09%
50.00%
42.07%
-25.66%
Next earnings: July 26, 2026 (58 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
8.6%
66.7%
9
Feb
3.1%
55.6%
9
Mar
-7.6%
22.2%
9
Apr
2.4%
44.4%
9
May
2.8%
50.0%
8
Jun
7.5%
50.0%
8
Jul
0.5%
50.0%
8
Aug
0.1%
62.5%
8
Sep
-5.6%
37.5%
8
Oct
-4.7%
44.4%
9
Nov
10.1%
55.6%
9
Dec
-2.9%
44.4%
9
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
-0.09%
49.0%
408
Tuesday
0.24%
51.1%
450
Wednesday
0.23%
50.6%
445
Thursday
-0.27%
45.7%
438
Friday
0.25%
49.4%
439
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 29.2%
Insider Transactions — Smart Summary
Total insider ownership: 2.0%
Founder-led management: Samantha Du (Founder, Chairperson & CEO)
12-Month Insider Activity Summary
Total Filings
43
Net Value
-$20.2M
Net Shares Change
270,557
% of Float
0.0%
C-Suite Filings
41
Clusters Detected
4
Key Insiders
Name
Title
Net Value
Filings
Activity
Smiley Joshua L
President and Chief Operating Officer
-$294,343.724
3
3 sell
Amado Rafael
President, Head of Global Oncology Research and Development
-$257,147.896
2
2 sell
Chen Yajing
Chief Financial Officer
-$137,731.094
2
2 sell
Edmondson Frazor Titus III
Chief Legal Officer
-$134,406.48
3
3 sell
Transaction Clusters
Period
Filings
Insiders
Net Value
Seniority
2025-06-23 – 2025-07-03
6
4
-$2.2M
5 C-suite
2025-08-12 – 2025-08-19
7
5
-$7.3M
7 C-suite
2026-03-05 – 2026-03-19
10
6
-$5.9M
9 C-suite
2026-04-03 – 2026-04-08
10
5
-$917,729.998
10 C-suite
Significant Filings
Date
Insider
Title
Net Value
Price After
2026-04-03
Smiley Joshua L
President and Chief Operating Officer
-$196,029.46
Transaction at $20.39, now -8.3%
2026-04-03
Edmondson Frazor Titus III
Chief Legal Officer
-$85,515.66
Transaction at $20.39, now -8.3%
2026-04-03
Chen Yajing
Chief Financial Officer
-$106,007.61
Transaction at $20.39, now -8.3%
2026-04-03
Amado Rafael
President, Head of Global Oncology Research and Development
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