INO — Inovio Pharmaceuticals Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates INO Bearish with a Setup Score of 57, net conviction 53, actionability 62. How the Setup Score works →

Total Setup Score57
Directional BiasBearish
Net Conviction53
Actionability62 (in range)

Key signals behind this score

About Inovio Pharmaceuticals Inc

Inovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses SynCon, to help engineer precisely designed plasmid DNA plasmids, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$1.26
Market Cap$125M
Float96.2M
Shares Outstanding103.4M
P/E (Forward)16.58
Price/Sales (TTM)961.51
vs. Analyst Target+151.3% to analyst PT
Dividend RateNone
Analyst Target Price$3.17 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $7.4M -$166M $7.4M -$150M
2021 $1.8M -$304M $1.8M -$297M
2022 $10.3M -$280M $10.3M -$271M
2023 $832,010 -$135M $832,010 -$130M
2024 $217,756 -$107M -$2.9M -$104M
2025 $65,343 -$84.9M $65,343 -$82.0M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 N/A -$45.5M
Dec 2025 -$65,343 $3.8M
Mar 2026 N/A -$19.7M
Jun 2026 N/A -$6.01B

Ownership & Float

Insider Ownership0.3%
Institutional Ownership46.0%
Short Float16.7%
% of All Funds Holding1.19%
Number of Funds Holding105

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$1.05Near-term / short-term trend
Weekly40-Week SMA$1.42Medium-term trend
Weekly80-Week SMA$1.70Cyclical trend (business cycle)
Weekly200-Week SMA$6.15Secular trend (multi-year)
Monthly10-Month SMA$1.44Near-term monthly trend
Monthly20-Month SMA$1.73Medium-term monthly trend
Monthly40-Month SMA$4.29Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$0.70 support 2.00x 0 months ago
$4.30 resistance 2.93x 19 months ago

Historical Earnings Reactions (94 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -2.06% -0.77% 28.72% 23.27% -29.81%
1 Day -2.11% -1.19% 34.04% 26.19% -42.01%
1 Week -2.58% -2.91% 40.43% 25.85% -35.58%
2 Weeks -2.39% -4.99% 40.43% 65.10% -33.54%
1 Month -2.82% -5.65% 39.78% 59.26% -62.68%

Next earnings: October 17, 2026 (50 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan12.8%60.7%28
Feb1.4%39.3%28
Mar1.0%42.9%28
Apr-1.8%35.7%28
May-0.2%46.4%28
Jun3.9%42.9%28
Jul2.6%35.7%28
Aug-0.3%51.9%27
Sep-5.2%37.0%27
Oct-0.5%40.7%27
Nov0.3%44.4%27
Dec1.9%29.6%27

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.05% 42.1% 1308
Tuesday -0.11% 40.3% 1430
Wednesday 0.53% 42.1% 1431
Thursday -0.05% 44.3% 1404
Friday 0.26% 43.6% 1395

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 46.0%

Insider Transactions — Smart Summary

Total insider ownership: 0.3%

Full insider transaction history and smart buy/sell sentiment summary available on Trend Edge.

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Inovio Pharmaceuticals Inc (INO) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for INO on Trend Edge →