INO — Inovio Pharmaceuticals Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates INO Bearish with a Setup Score of 0, net conviction 47, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBearish
Net Conviction47
Actionability0 (extended)

Key signals behind this score

About Inovio Pharmaceuticals Inc

Inovio Pharmaceuticals, Inc., a biotechnology company, focuses on the discovery, development, and commercialization of DNA medicines to treat and protect people from diseases associated with human papillomavirus (HPV), cancer, and infectious diseases. Its DNA medicines platform uses SynCon, to help engineer precisely designed plasmid DNA plasmids, as well as CELLECTRA smart devices technology that facilitates delivery of the DNA plasmids. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$1.16
Market Cap$97.9M
Float81.9M
Shares Outstanding82.3M
P/E (Forward)16.58
Price/Sales (TTM)1,712.37
vs. Analyst Target+402.2% to analyst PT
Dividend RateNone
Analyst Target Price$5.83 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $7.4M -$166M $7.4M -$150M
2021 $1.8M -$304M $1.8M -$297M
2022 $10.3M -$280M $10.3M -$271M
2023 $832,010 -$135M $832,010 -$130M
2024 $217,756 -$107M -$2.9M -$104M
2025 $65,343 -$84.9M $65,343 -$82.0M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$23.5M
Sep 2025 N/A -$45.5M
Dec 2025 -$65,343 $3.8M
Mar 2026 N/A -$19.7M

Ownership & Float

Insider Ownership0.4%
Institutional Ownership47.3%
Short Float19.8%
% of All Funds Holding1.12%
Number of Funds Holding92

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$1.19Near-term / short-term trend
Weekly40-Week SMA$1.60Medium-term trend
Weekly80-Week SMA$1.78Cyclical trend (business cycle)
Weekly200-Week SMA$6.76Secular trend (multi-year)
Monthly10-Month SMA$1.60Near-term monthly trend
Monthly20-Month SMA$1.78Medium-term monthly trend
Monthly40-Month SMA$4.50Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$4.30 resistance 2.93x 18 months ago
$5.30 resistance 1.04x 19 months ago

Historical Earnings Reactions (93 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -1.76% -0.75% 29.03% 23.27% -22.40%
1 Day -1.74% -1.19% 34.41% 26.19% -42.01%
1 Week -2.23% -2.56% 40.86% 25.85% -33.33%
2 Weeks -2.27% -4.80% 40.86% 65.10% -33.54%
1 Month -2.66% -5.61% 40.22% 59.26% -62.68%

Next earnings: August 11, 2026 (28 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan12.8%60.7%28
Feb1.4%39.3%28
Mar1.0%42.9%28
Apr-1.8%35.7%28
May-0.2%46.4%28
Jun3.9%42.9%28
Jul4.2%37.0%27
Aug-0.3%51.9%27
Sep-5.2%37.0%27
Oct-0.5%40.7%27
Nov0.3%44.4%27
Dec1.9%29.6%27

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.07% 42.0% 1301
Tuesday -0.12% 40.2% 1424
Wednesday 0.52% 42.0% 1425
Thursday -0.02% 44.4% 1398
Friday 0.25% 43.6% 1389

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 47.3%

Insider Transactions — Smart Summary

Total insider ownership: 0.4%

Full insider transaction history and smart buy/sell sentiment summary available on Trend Edge.

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Inovio Pharmaceuticals Inc (INO) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for INO on Trend Edge →