XNCR — Xencor Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates XNCR Bearish with a Setup Score of 0, net conviction 24, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBearish
Net Conviction24
Actionability0 (no mans land)

Key signals behind this score

About Xencor Inc

Xencor, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of engineered antibodies for the treatment of cancer and autoimmune diseases. The company provides Ultomiris to treat patients with atypical hemolytic uremic syndrome, generalized myasthenia gravis, and neuromyelitis optica spectrum disororder; and Monjuvi for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$15.85
Market Cap$1.19B
Float54.4M
Shares Outstanding74.1M
P/E (Forward)68.03
Price/Sales (TTM)12.27
vs. Analyst Target+78.8% to analyst PT
Profit Margin-177.10%
Operating Margin (TTM)-1724.14%
Revenue (TTM)$97.4M
Dividend RateNone
Analyst Target Price$28.33 (12 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $123M -$63.5M $123M -$71.0M
2021 $275M $82.6M $275M $51.3M
2022 $165M -$55.2M $165M -$73.7M
2023 $168M -$126M -$85.3M -$126M
2024 $110M -$233M -$117M -$186M
2025 $126M -$91.9M $115M -$47.0M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $43.6M -$30.8M
Sep 2025 $21.0M -$6.0M
Dec 2025 $28.2M -$6.7M
Mar 2026 $4.5M -$129M

Ownership & Float

Insider Ownership1.2%
Institutional Ownership115.4%
Short Float20.7%
% of All Funds Holding2.28%
Number of Funds Holding187

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$12.99Near-term / short-term trend
Weekly40-Week SMA$13.42Medium-term trend
Weekly80-Week SMA$12.45Cyclical trend (business cycle)
Weekly200-Week SMA$19.22Secular trend (multi-year)
Monthly10-Month SMA$14.00Near-term monthly trend
Monthly20-Month SMA$13.12Medium-term monthly trend
Monthly40-Month SMA$17.41Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$11.90 support 1.06x 0 months ago
$11.70 support 1.78x 8 months ago
$8.20 support 1.50x 9 months ago
$26.70 resistance 1.33x 18 months ago

Historical Earnings Reactions (50 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.68% 0.21% 54.00% 15.42% -9.44%
1 Day -0.39% -0.43% 46.00% 10.31% -20.03%
1 Week -0.85% -1.12% 44.00% 12.24% -17.31%
2 Weeks 0.00% -0.30% 48.00% 30.57% -21.04%
1 Month 1.72% 0.36% 51.02% 38.91% -24.83%

Next earnings: August 5, 2026 (25 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-6.1%23.1%13
Feb4.6%61.5%13
Mar-5.2%23.1%13
Apr-3.6%15.4%13
May1.7%53.8%13
Jun10.8%61.5%13
Jul0.1%58.3%12
Aug-1.6%41.7%12
Sep1.7%41.7%12
Oct0.6%50.0%12
Nov14.9%91.7%12
Dec0.6%50.0%12

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.07% 47.7% 593
Tuesday 0.02% 48.6% 652
Wednesday 0.32% 51.2% 648
Thursday -0.20% 44.7% 637
Friday 0.18% 50.7% 633

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 115.4%

Insider Transactions — Smart Summary

Total insider ownership: 1.2%

Founder-led management: Bassil Dahiyat (Chief Executive Officer, President & Director)

12-Month Insider Activity Summary

Total Filings15
Net Value-$960,612.858
Net Shares Change77,395
% of Float0.1%
C-Suite Filings10
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
Dahiyat Bassil I PRESIDENT & CEO -$320,402.862 2 2 sell
Desjarlais John R SR. VICE PRESIDENT & CSO -$105,557.175 2 2 sell
Feigal Ellen -$89,369.58 1 N/A
Eckert Celia SVP, GENERAL COUNSEL -$73,699.814 2 2 sell
Cornelissen Bart Jan SR. VICE PRESIDENT & CFO -$71,295.387 2 2 sell
RANIERI RICHARD J -$67,384.94 1 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2026-03-04 – 2026-03-09 7 4 -$527,964.775 7 C-suite
2026-06-17 – 2026-06-22 5 5 -$379,134.67

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-04-13 Cornelissen Bart Jan SR. VICE PRESIDENT & CFO -$42,990.464 Transaction at $12.29, now +29.0%
2026-03-04 Eckert Celia SVP, GENERAL COUNSEL -$17,747.489 Transaction at $11.90, now +33.2%
2026-03-04 Dahiyat Bassil I PRESIDENT & CEO -$80,387.086 Transaction at $11.90, now +33.2%
2026-03-09 Eckert Celia SVP, GENERAL COUNSEL -$55,952.325 Transaction at $11.17, now +42.0%
2026-03-04 Desjarlais John R SR. VICE PRESIDENT & CSO -$31,676.651 Transaction at $11.90, now +33.2%
2026-03-09 Desjarlais John R SR. VICE PRESIDENT & CSO -$73,880.524 Transaction at $11.16, now +42.0%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Xencor Inc (XNCR) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for XNCR on Trend Edge →