TWST — Twist Bioscience Corp

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Twist Bioscience Corp

Twist Bioscience Corporation manufactures and sells synthetic DNA-based products. The company offers synthetic genes and gene fragments used in product development for therapeutics, diagnostics, chemicals/materials, food/agriculture, data storage, and various applications within academic research by biotech, pharma, industrial chemical, and agricultural companies, as well as academic labs; Oligo pools used in targeted NGS, CRISPR gene editing, mu… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$64.17
Market Cap$3.34B
Float55.4M
Shares Outstanding62.3M
Price/Sales (TTM)8.16
vs. Analyst Target-1.3% to analyst PT
Profit Margin-19.85%
Operating Margin (TTM)-34.92%
Revenue (TTM)$409M
Dividend RateNone
Analyst Target Price$63.33 (12 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $90.1M -$140M $28.7M -$132M
2021 $132M -$152M $51.7M -$144M
2022 $204M -$218M $84.2M -$247M
2023 $245M -$205M $89.7M -$174M
2024 $313M -$209M $133M -$177M
2025 $377M -$77.7M $191M -$52.1M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $96.1M $20.4M
Sep 2025 $99.0M -$27.1M
Dec 2025 $104M -$30.5M
Mar 2026 $111M -$44.0M

Ownership & Float

Insider Ownership1.3%
Institutional Ownership123.9%
Short Float25.1%
% of All Funds Holding3.15%
Number of Funds Holding259

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$55.46Near-term / short-term trend
Weekly40-Week SMA$40.27Medium-term trend
Weekly80-Week SMA$39.94Cyclical trend (business cycle)
Weekly200-Week SMA$34.67Secular trend (multi-year)
Monthly10-Month SMA$40.99Near-term monthly trend
Monthly20-Month SMA$40.71Medium-term monthly trend
Monthly40-Month SMA$35.32Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$28.20 support 1.56x 6 months ago

Historical Earnings Reactions (31 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.20% 0.23% 54.84% 19.59% -18.82%
1 Day 0.16% 0.80% 54.84% 28.74% -20.05%
1 Week -0.22% -0.85% 41.94% 32.36% -15.05%
2 Weeks 1.22% 2.75% 54.84% 46.86% -30.58%
1 Month 2.38% 0.85% 53.33% 65.04% -36.03%

Next earnings: July 23, 2026 (56 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan7.8%75.0%8
Feb-3.4%37.5%8
Mar-6.0%37.5%8
Apr-3.7%50.0%8
May7.9%71.4%7
Jun19.6%100.0%7
Jul11.6%71.4%7
Aug-8.2%14.3%7
Sep-3.7%42.9%7
Oct-1.6%42.9%7
Nov21.3%62.5%8
Dec2.1%25.0%8

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.36% 53.1% 356
Tuesday 0.21% 48.2% 392
Wednesday 0.30% 52.3% 388
Thursday -0.04% 46.7% 381
Friday 0.20% 51.8% 382

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 123.9%

Insider Transactions — Smart Summary

Total insider ownership: 1.3%

Founder-led management: Emily Leproust (Co-Founder, Board Chair & CEO)

12-Month Insider Activity Summary

Total Filings122
Net Value-$18.0M
Net Shares Change-408,264
% of Float-0.7%
C-Suite Filings115
Clusters Detected16

Key Insiders

NameTitleNet ValueFilingsActivity
Finn Patrick John President and COO -$3.0M 2 N/A
Green Paula SVP of Human Resources -$2.1M 1 1 sell
JOHANNESSEN JAN -$785,314.62 3 2 sell
WERNER ROBERT F. Chief Accounting Officer -$609,873.441 2 2 sell
Laponis Adam Chief Financial Officer -$240,000 1 N/A
Cho Dennis Senior Vice President, Chief Legal Officer and Corporate Secretary -$124,756.812 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-05-28 – 2025-06-10 5 4 -$134,547.542 5 C-suite
2025-06-18 – 2025-06-24 4 3 -$81,807.65 4 C-suite
2025-07-07 – 2025-07-11 5 5 -$127,875.29 5 C-suite
2025-07-25 – 2025-08-06 6 5 -$391,777.912 6 C-suite
2025-08-25 – 2025-08-27 7 6 -$201,525.751 7 C-suite
2025-09-10 – 2025-09-24 8 4 -$158,202.112 8 C-suite
2025-10-06 – 2025-10-10 11 6 -$2.7M 11 C-suite
2025-10-27 – 2025-11-05 12 6 -$2.6M 12 C-suite
2025-11-20 – 2025-11-25 7 7 -$381,218.232 6 C-suite
2025-12-10 – 2025-12-23 7 4 -$199,713.592 7 C-suite
2026-02-05 – 2026-02-19 12 8 -$6.1M 10 C-suite
2026-02-25 – 2026-03-10 10 6 -$1.0M 10 C-suite
2026-03-19 – 2026-03-24 4 4 -$455,880.855 3 C-suite
2026-04-21 – 2026-04-29 4 4 -$957,600.377 3 C-suite
2026-05-06 – 2026-05-14 7 6 -$1.4M 6 C-suite
2026-05-26 – 2026-05-26 6 6 -$894,504.572 6 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-05-12 WERNER ROBERT F. Chief Accounting Officer -$282,186.641 Transaction at $56.88, now +12.8%
2026-05-14 JOHANNESSEN JAN -$505,440 Transaction at $35.06, now +83.0%
2026-02-19 Green Paula SVP of Human Resources -$2.1M Transaction at $52.40, now +22.5%
2026-02-05 WERNER ROBERT F. Chief Accounting Officer -$327,686.8 Transaction at $46.11, now +39.2%
2025-10-08 Cho Dennis Senior Vice President, Chief Legal Officer and Corporate Secretary -$124,756.812 Transaction at $32.19, now +99.4%
2025-11-20 JOHANNESSEN JAN -$174,479.88 Transaction at $24.77, now +159.1%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Twist Bioscience Corp (TWST) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for TWST on Trend Edge →