Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge rates TSHA Bullish with a Setup Score of 25, net conviction 44, actionability 14. How the Setup Score works →
| Total Setup Score | 25 |
|---|---|
| Directional Bias | Bullish |
| Net Conviction | 44 |
| Actionability | 14 (in range) |
Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease… Read full Trend Edge analysis →
| Current Price | $6.34 |
|---|---|
| Market Cap | $1.89B |
| Float | 205.9M |
| Shares Outstanding | 287.4M |
| Price/Sales (TTM) | 252.71 |
| vs. Analyst Target | +105.0% to analyst PT |
| Operating Margin (TTM) | -1774.37% |
| Revenue (TTM) | $7.5M |
| Dividend Rate | None |
| Analyst Target Price | $13.00 (10 analysts) |
| Year | Revenue | Net Income | Gross Profit | EBITDA |
|---|---|---|---|---|
| 2020 | N/A | -$43.0M | -$9,000 | -$60.0M |
| 2021 | N/A | -$175M | -$492,000 | -$173M |
| 2022 | $2.5M | -$166M | $14,999 | -$160M |
| 2023 | $15.5M | -$112M | $15.5M | -$105M |
| 2024 | $8.3M | -$89.3M | $8.3M | -$88.0M |
| 2025 | $9.8M | -$109M | $9.8M | -$108M |
| Quarter | Revenue | Net Income |
|---|---|---|
| Jun 2025 | $2.0M | -$26.9M |
| Sep 2025 | N/A | -$32.7M |
| Dec 2025 | $5.5M | -$27.9M |
| Mar 2026 | N/A | -$42.4M |
| Insider Ownership | 9.6% |
|---|---|
| Institutional Ownership | 86.2% |
| Short Float | 18.8% |
| % of All Funds Holding | 2.14% |
| Number of Funds Holding | 176 |
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
| Timeframe | SMA | Value | Trend Context |
|---|---|---|---|
| Weekly | 10-Week SMA | $6.10 | Near-term / short-term trend |
| Weekly | 40-Week SMA | $5.18 | Medium-term trend |
| Weekly | 80-Week SMA | $3.74 | Cyclical trend (business cycle) |
| Weekly | 200-Week SMA | $2.65 | Secular trend (multi-year) |
| Monthly | 10-Month SMA | $5.41 | Near-term monthly trend |
| Monthly | 20-Month SMA | $3.81 | Medium-term monthly trend |
| Monthly | 40-Month SMA | $2.96 | Secular monthly trend |
Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
| Price Level | Type | Volume Ratio | Age |
|---|---|---|---|
| $3.30 | support | 2.96x | 8 months ago |
| $2.00 | support | 1.79x | 13 months ago |
| Timeframe | Avg Return | Median | Win Rate | Best | Worst |
|---|---|---|---|---|---|
| Gap | 2.02% | 0.89% | 70.83% | 31.11% | -15.44% |
| 1 Day | 1.69% | -0.46% | 41.67% | 31.56% | -27.52% |
| 1 Week | 0.57% | 0.38% | 50.00% | 40.89% | -41.28% |
| 2 Weeks | 2.54% | 2.02% | 58.33% | 58.69% | -36.58% |
| 1 Month | 4.07% | 3.78% | 56.52% | 56.81% | -34.51% |
Next earnings: August 11, 2026 (31 days away)
Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).
| Day | Avg Return | Win Rate | Samples |
|---|---|---|---|
| Monday | 0.42% | 48.3% | 271 |
| Tuesday | 0.47% | 48.3% | 300 |
| Wednesday | 0.04% | 47.3% | 298 |
| Thursday | -0.12% | 44.5% | 290 |
| Friday | 0.01% | 43.4% | 290 |
Institutional holder breakdown coming soon.
Total institutional ownership: 86.2%
Total insider ownership: 9.6%
Founder-led management: Steven Gray (Chief Scientific Advisor of UT Southwestern Gene Therapy Program), Berge Minassian (Chief Medical Advisor of UT Southwestern Gene Therapy Program)
| Total Filings | 10 |
|---|---|
| Net Value | -$5.5M |
| Net Shares Change | -422,997 |
| % of Float | -0.2% |
| C-Suite Filings | 10 |
| Clusters Detected | 1 |
| Name | Title | Net Value | Filings | Activity |
|---|---|---|---|---|
| Nagendran Sukumar | President and Head of R&D | -$4.0M | 6 | 3 sell |
| Nolan Sean P. | Chief Executive Officer | -$840,191.468 | 1 | 1 sell |
| Alam Kamran | CHIEF FINANCIAL OFFICER | -$647,819.148 | 3 | 3 sell |
| Period | Filings | Insiders | Net Value | Seniority |
|---|---|---|---|---|
| 2026-01-14 – 2026-01-27 | 4 | 3 | -$2.6M | 4 C-suite |
| Date | Insider | Title | Net Value | Price After |
|---|---|---|---|---|
| 2026-01-27 | Nagendran Sukumar | President and Head of R&D | -$547,465.875 | Transaction at $4.72, now +34.4% |
| 2026-01-27 | Alam Kamran | CHIEF FINANCIAL OFFICER | -$485,039.198 | Transaction at $4.72, now +34.4% |
| 2026-01-27 | Nolan Sean P. | Chief Executive Officer | -$840,191.468 | Transaction at $4.72, now +34.4% |
| 2026-02-06 | Alam Kamran | CHIEF FINANCIAL OFFICER | -$7,480.6 | Transaction at $4.52, now +40.3% |
| 2026-04-13 | Nagendran Sukumar | President and Head of R&D | -$859,474.09 | Transaction at $3.08, now +105.5% |
| 2025-08-22 | Nagendran Sukumar | President and Head of R&D | -$162,603.9 | Transaction at $2.85, now +122.5% |
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Taysha Gene Therapies Inc (TSHA) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
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Get the full AI Consult analysis for TSHA on Trend Edge →