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Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease… Read full Trend Edge analysis →
| Current Price | $5.59 |
|---|---|
| Market Cap | $1.58B |
| Float | 197.0M |
| Shares Outstanding | 287.4M |
| Price/Sales (TTM) | 211.16 |
| vs. Analyst Target | +118.8% to analyst PT |
| Operating Margin (TTM) | -1774.37% |
| Revenue (TTM) | $7.5M |
| Dividend Rate | None |
| Analyst Target Price | $12.23 (10 analysts) |
| Year | Revenue | Net Income | Gross Profit | EBITDA |
|---|---|---|---|---|
| 2020 | N/A | -$43.0M | -$9,000 | -$60.0M |
| 2021 | N/A | -$175M | -$492,000 | -$173M |
| 2022 | $2.5M | -$166M | $14,999 | -$160M |
| 2023 | $15.5M | -$112M | $15.5M | -$105M |
| 2024 | $8.3M | -$89.3M | $8.3M | -$88.0M |
| 2025 | $9.8M | -$109M | $9.8M | -$108M |
| Quarter | Revenue | Net Income |
|---|---|---|
| Jun 2025 | $2.0M | -$26.9M |
| Sep 2025 | N/A | -$32.7M |
| Dec 2025 | $5.5M | -$27.9M |
| Mar 2026 | N/A | -$42.4M |
| Insider Ownership | 10.6% |
|---|---|
| Institutional Ownership | 95.7% |
| Short Float | 20.3% |
| % of All Funds Holding | 2.14% |
| Number of Funds Holding | 176 |
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
| Timeframe | SMA | Value | Trend Context |
|---|---|---|---|
| Weekly | 10-Week SMA | $5.59 | Near-term / short-term trend |
| Weekly | 40-Week SMA | $4.76 | Medium-term trend |
| Weekly | 80-Week SMA | $3.45 | Cyclical trend (business cycle) |
| Weekly | 200-Week SMA | $2.58 | Secular trend (multi-year) |
| Monthly | 10-Month SMA | $4.69 | Near-term monthly trend |
| Monthly | 20-Month SMA | $3.39 | Medium-term monthly trend |
| Monthly | 40-Month SMA | $2.67 | Secular monthly trend |
Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
| Price Level | Type | Volume Ratio | Age |
|---|---|---|---|
| $3.30 | support | 2.96x | 6 months ago |
| $2.00 | support | 1.79x | 11 months ago |
| Timeframe | Avg Return | Median | Win Rate | Best | Worst |
|---|---|---|---|---|---|
| Gap | 2.02% | 0.89% | 70.83% | 31.11% | -15.44% |
| 1 Day | 1.69% | -0.46% | 41.67% | 31.56% | -27.52% |
| 1 Week | 0.57% | 0.38% | 50.00% | 40.89% | -41.28% |
| 2 Weeks | 2.54% | 2.02% | 58.33% | 58.69% | -36.58% |
| 1 Month | 4.07% | 3.78% | 56.52% | 56.81% | -34.51% |
Next earnings: July 25, 2026 (59 days away)
Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).
| Day | Avg Return | Win Rate | Samples |
|---|---|---|---|
| Monday | 0.39% | 47.9% | 265 |
| Tuesday | 0.48% | 48.3% | 294 |
| Wednesday | 0.02% | 46.9% | 292 |
| Thursday | -0.13% | 44.0% | 284 |
| Friday | 0.02% | 43.4% | 286 |
Institutional holder breakdown coming soon.
Total institutional ownership: 95.7%
Total insider ownership: 10.6%
Founder-led management: Steven Gray (Chief Scientific Advisor of UT Southwestern Gene Therapy Program), Berge Minassian (Chief Medical Advisor of UT Southwestern Gene Therapy Program)
| Total Filings | 11 |
|---|---|
| Net Value | -$5.5M |
| Net Shares Change | 327,003 |
| % of Float | 0.2% |
| C-Suite Filings | 10 |
| Clusters Detected | 1 |
| Name | Title | Net Value | Filings | Activity |
|---|---|---|---|---|
| Nagendran Sukumar | President and Head of RandD | -$3.4M | 5 | 3 sell |
| Manning Paul B | +$2.1M | 1 | 1 buy | |
| Nolan Sean P. | Chief Executive Officer | -$840,191.468 | 1 | 1 sell |
| Alam Kamran | CHIEF FINANCIAL OFFICER | -$647,819.148 | 3 | 3 sell |
| Period | Filings | Insiders | Net Value | Seniority |
|---|---|---|---|---|
| 2026-01-14 – 2026-01-27 | 4 | 3 | -$2.6M | 4 C-suite |
| Date | Insider | Title | Net Value | Price After |
|---|---|---|---|---|
| 2026-01-27 | Nagendran Sukumar | President and Head of RandD | -$547,465.875 | Transaction at $4.72, now +18.5% |
| 2026-01-27 | Alam Kamran | CHIEF FINANCIAL OFFICER | -$485,039.198 | Transaction at $4.72, now +18.5% |
| 2026-01-27 | Nolan Sean P. | Chief Executive Officer | -$840,191.468 | Transaction at $4.72, now +18.5% |
| 2025-06-03 | Manning Paul B | +$2.1M | Transaction at $2.75, now +103.3% | |
| 2025-12-01 | Nagendran Sukumar | President and Head of RandD | -$1.1M | Transaction at $3.05, now +83.3% |
| 2026-02-06 | Alam Kamran | CHIEF FINANCIAL OFFICER | -$7,480.6 | Transaction at $4.52, now +23.7% |
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