Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge Setup Score
Trend Edge rates STOK Bullish with a Setup Score of 55, net conviction 45, actionability 67. How the Setup Score works →
Total Setup Score
55
Directional Bias
Bullish
Net Conviction
45
Actionability
67 (in range)
Key signals behind this score
40wk Uptrend — trend only (sma 31.67 vs px 31.38)
Fresh Trend Turn — 200wk turn 30w+40wk turn 48w
80wk Uptrend — rising+above (sma 22.03 vs px 31.38)
200wk Uptrend — rising+above (sma 14.67 vs px 31.38)
Funds Accumulating — momZ +1.31 · 2.07→2.17
Short Squeeze Setup — velZ +0.69 · age 60w×0.64 · 25.07%
Founder-Led — founder/CEO led
About Stoke Therapeutics Inc
Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels. Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of autosomal dominant optic atrophy… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: June 19, 2019
Headquarters: 45 Wiggins Avenue, Bedford, MA, United States, 01730
Founder-Led: Yes — Isabel Aznarez (Co-Founder, Head of Research & Senior VP)
Key Metrics
Current Price
$31.38
Market Cap
$2.04B
Float
46.8M
Shares Outstanding
62.3M
P/E (Forward)
204.08
Price/Sales (TTM)
63.74
vs. Analyst Target
+46.6% to analyst PT
Operating Margin (TTM)
-857.57%
Revenue (TTM)
$32.1M
Dividend Rate
None
Analyst Target Price
$46.00 (10 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
N/A
-$50.6M
-$1.9M
-$52.2M
2021
$3.0M
-$84.7M
-$2.2M
-$85.1M
2022
$12.4M
-$93.1M
$12.4M
-$103M
2023
$8.8M
-$105M
$8.8M
-$102M
2024
$36.6M
-$89.0M
$36.6M
-$86.8M
2025
$184M
-$6.9M
$184M
-$5.1M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$13.8M
-$23.5M
Sep 2025
$10.6M
-$38.3M
Dec 2025
$1.4M
-$57.9M
Mar 2026
$6.2M
-$50.0M
Ownership & Float
Insider Ownership
3.8%
Institutional Ownership
120.2%
Short Float
25.1%
% of All Funds Holding
2.17%
Number of Funds Holding
178
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$31.01
Near-term / short-term trend
Weekly
40-Week SMA
$31.67
Medium-term trend
Weekly
80-Week SMA
$22.03
Cyclical trend (business cycle)
Weekly
200-Week SMA
$14.67
Secular trend (multi-year)
Monthly
10-Month SMA
$31.97
Near-term monthly trend
Monthly
20-Month SMA
$22.18
Medium-term monthly trend
Monthly
40-Month SMA
$15.87
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$23.50
support
1.67x
8 months ago
$19.80
support
1.30x
9 months ago
$12.60
support
1.20x
10 months ago
$6.60
support
1.35x
14 months ago
Historical Earnings Reactions (29 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
3.27%
0.30%
58.62%
70.31%
-13.42%
1 Day
3.95%
0.67%
65.52%
58.31%
-9.94%
1 Week
6.15%
4.23%
65.52%
97.15%
-16.57%
2 Weeks
4.82%
2.24%
58.62%
96.31%
-25.59%
1 Month
7.85%
1.60%
53.57%
90.92%
-28.21%
Next earnings: August 11, 2026 (30 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
-3.4%
28.6%
7
Feb
3.9%
42.9%
7
Mar
1.1%
28.6%
7
Apr
-3.0%
42.9%
7
May
12.7%
57.1%
7
Jun
-1.1%
42.9%
7
Jul
-3.8%
57.1%
7
Aug
13.9%
57.1%
7
Sep
-10.4%
28.6%
7
Oct
11.0%
71.4%
7
Nov
-2.5%
42.9%
7
Dec
12.3%
71.4%
7
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.00%
50.0%
332
Tuesday
0.49%
52.5%
366
Wednesday
0.06%
49.2%
362
Thursday
-0.03%
47.3%
355
Friday
0.14%
49.4%
354
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 120.2%
Insider Transactions — Smart Summary
Total insider ownership: 3.8%
Founder-led management: Isabel Aznarez (Co-Founder, Head of Research & Senior VP)
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Stoke Therapeutics Inc
(STOK) powered by Claude Opus — Anthropic's most capable AI model.
The analysis covers five layers:
technical analysis (near-term, medium-term, cyclical, and secular trend, momentum,
volume shelf support and resistance, breakout and breakdown signals),
qualitative analysis (business model, competitive moat, sector dynamics),
insider sentiment (buy and sell signals from executive and director transactions),
share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and
fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit,
stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward.
Whether you are building a long position, initiating a short, or looking for a reversal setup,
AI Consult identifies the highest-probability signal from the current trend.