SRPT — Sarepta Therapeutics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates SRPT Bearish with a Setup Score of 53, net conviction 45, actionability 62. How the Setup Score works →

Total Setup Score53
Directional BiasBearish
Net Conviction45
Actionability62 (in range)

Key signals behind this score

About Sarepta Therapeutics Inc

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, siRNA platform, gene therapy, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 for the treatment of Duchenne in patients who have a confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of Duchenne in … Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$17.85
Market Cap$1.92B
Float100.5M
Shares Outstanding105.6M
P/E (Forward)19.16
Price/Sales (TTM)0.97
vs. Analyst Target+21.2% to analyst PT
Profit Margin-6.93%
Operating Margin (TTM)13.03%
Revenue (TTM)$1.97B
Earnings Growth (YoY)2663.80%
Dividend RateNone
Analyst Target Price$21.64 (24 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $540M -$554M $477M -$453M
2021 $702M -$419M $605M -$317M
2022 $933M -$703M $793M -$595M
2023 $1.24B -$536M $1.09B -$454M
2024 $1.90B $235M $1.58B $317M
2025 $2.20B -$713M $1.32B -$648M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $399M -$180M
Dec 2025 $443M -$283M
Mar 2026 $731M $331M
Jun 2026 $401M -$4.9M

Ownership & Float

Insider Ownership4.9%
Institutional Ownership104.1%
Short Float24.5%
% of All Funds Holding3.64%
Number of Funds Holding320

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$19.16Near-term / short-term trend
Weekly40-Week SMA$18.78Medium-term trend
Weekly80-Week SMA$22.82Cyclical trend (business cycle)
Weekly200-Week SMA$81.58Secular trend (multi-year)
Monthly10-Month SMA$18.75Near-term monthly trend
Monthly20-Month SMA$24.46Medium-term monthly trend
Monthly40-Month SMA$72.00Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$37.80 resistance 3.12x 15 months ago
$62.00 resistance 3.34x 16 months ago
$106.00 resistance 1.91x 18 months ago

Historical Earnings Reactions (112 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.29% 0.00% 43.75% 22.63% -37.67%
1 Day -1.04% -0.79% 45.54% 20.10% -33.74%
1 Week -0.77% -0.43% 47.32% 36.25% -34.62%
2 Weeks 1.50% 0.38% 50.00% 74.34% -48.08%
1 Month 3.27% 2.07% 54.95% 86.97% -49.55%

Next earnings: November 2, 2026 (22 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan9.1%51.7%29
Feb1.6%41.4%29
Mar-0.9%41.4%29
Apr3.5%37.9%29
May3.8%48.3%29
Jun1.0%51.7%29
Jul4.0%43.3%30
Aug5.9%60.0%30
Sep4.8%46.7%30
Oct-1.3%51.7%29
Nov3.1%48.3%29
Dec-2.4%55.2%29

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.12% 46.6% 1387
Tuesday 0.03% 47.2% 1515
Wednesday 0.45% 46.5% 1515
Thursday -0.12% 45.3% 1485
Friday 0.25% 46.6% 1477

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 104.1%

Insider Transactions — Smart Summary

Total insider ownership: 4.9%

12-Month Insider Activity Summary

Total Filings2
Net Value-$294,201.97
Net Shares Change-20,426
% of Float-0.0%
C-Suite Filings1
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
Estepan Ian Michael Chief Operating Officer -$294,201.97 1 1 sell
Mayo Stephen -$123,207.78 1 1 sell

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-12-18 Estepan Ian Michael Chief Operating Officer -$294,201.97 Transaction at $22.31, now -20.0%
2026-03-13 Mayo Stephen -$123,207.78 Transaction at $17.02, now +4.9%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Sarepta Therapeutics Inc (SRPT) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for SRPT on Trend Edge →