Stock analysis, trade plans, and proprietary indicators by Trend Edge.
About Syndax Pharmaceuticals Inc
Syndax Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidate includes Revuforj (revumenib), a menin inhibitor for the treatment of relapsed or refractory R/R acute leukemia; and Niktimvo (axatilimab-csfr), a colony stimulating factor-1 receptor blocking antibody to treat chronic graft-versus-host disease. Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: March 3, 2016
Headquarters: 730 Third Avenue, New York, NY, United States, 10017
Founder-Led: Yes — Peter Ordentlich (Chief Scientific Officer)
Key Metrics
Current Price
$19.61
Market Cap
$1.79B
Float
79.0M
Shares Outstanding
88.6M
Price/Sales (TTM)
8.22
vs. Analyst Target
+100.2% to analyst PT
Profit Margin
-112.01%
Operating Margin (TTM)
-52.73%
Revenue (TTM)
$217M
Dividend Rate
None
Analyst Target Price
$39.25 (12 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$1.5M
-$73.1M
$1.5M
-$71.3M
2021
$140M
$24.9M
$140M
$26.3M
2022
$127M
-$144M
-$454,000
-$152M
2023
N/A
-$209M
-$12,000
-$209M
2024
$23.7M
-$319M
$22.9M
-$314M
2025
$172M
-$285M
$165M
-$252M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$38.0M
-$71.8M
Sep 2025
$45.9M
-$60.7M
Dec 2025
$68.5M
-$68.0M
Mar 2026
$64.9M
-$42.7M
Ownership & Float
Insider Ownership
1.7%
Institutional Ownership
116.0%
Short Float
25.2%
% of All Funds Holding
2.70%
Number of Funds Holding
222
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$21.91
Near-term / short-term trend
Weekly
40-Week SMA
$19.48
Medium-term trend
Weekly
80-Week SMA
$16.09
Cyclical trend (business cycle)
Weekly
200-Week SMA
$19.04
Secular trend (multi-year)
Monthly
10-Month SMA
$19.27
Near-term monthly trend
Monthly
20-Month SMA
$16.38
Medium-term monthly trend
Monthly
40-Month SMA
$18.33
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$13.70
support
1.12x
5 months ago
$9.90
support
1.31x
8 months ago
Historical Earnings Reactions (41 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
-0.18%
-0.19%
43.90%
19.56%
-23.13%
1 Day
1.63%
0.31%
58.54%
21.68%
-21.59%
1 Week
1.49%
0.17%
51.22%
28.85%
-24.91%
2 Weeks
3.38%
-0.54%
48.78%
83.60%
-25.20%
1 Month
3.26%
-0.89%
47.50%
64.16%
-22.99%
Next earnings: July 19, 2026 (51 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
3.9%
60.0%
10
Feb
8.0%
70.0%
10
Mar
5.4%
60.0%
10
Apr
0.6%
36.4%
11
May
-1.9%
40.0%
10
Jun
-0.4%
50.0%
10
Jul
1.6%
60.0%
10
Aug
10.6%
60.0%
10
Sep
-3.1%
50.0%
10
Oct
-7.8%
20.0%
10
Nov
4.6%
60.0%
10
Dec
3.6%
50.0%
10
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.22%
50.6%
480
Tuesday
0.29%
49.8%
530
Wednesday
0.22%
50.0%
526
Thursday
-0.08%
46.3%
518
Friday
-0.06%
47.7%
518
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 116.0%
Insider Transactions — Smart Summary
Total insider ownership: 1.7%
Founder-led management: Peter Ordentlich (Chief Scientific Officer)
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Syndax Pharmaceuticals Inc
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The analysis covers five layers:
technical analysis (near-term, medium-term, cyclical, and secular trend, momentum,
volume shelf support and resistance, breakout and breakdown signals),
qualitative analysis (business model, competitive moat, sector dynamics),
insider sentiment (buy and sell signals from executive and director transactions),
share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and
fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
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