QURE — Uniqure NV

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Uniqure NV

uniQure N.V. develops treatments for patients suffering from rare and other devastating diseases in the United States. The company offers HEMGENIX that allows people living with hemophilia B to produce factor IX, which can lower the risk of bleeding. Its lead product candidate is AMT-130, a gene therapy candidate, which is in Phase I/II clinical study for the treatment of Huntington's disease. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$27.05
Market Cap$1.75B
Float49.9M
Shares Outstanding63.1M
P/E (Forward)27.93
Price/Sales (TTM)96.73
vs. Analyst Target+44.9% to analyst PT
Operating Margin (TTM)-1321.11%
Revenue (TTM)$18.1M
Earnings Growth (YoY)-18.20%
Dividend RateNone
Analyst Target Price$39.19 (13 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $37.5M -$125M -$84.9M -$127M
2021 $524M $330M $499M $319M
2022 $106M -$127M $103M -$108M
2023 $15.8M -$308M $2.2M -$253M
2024 $27.1M -$240M $8.8M -$161M
2025 $16.1M -$199M $14.4M -$117M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $5.3M -$37.7M
Sep 2025 $3.7M -$80.5M
Dec 2025 $5.6M -$37.1M
Mar 2026 $3.6M -$53.5M

Ownership & Float

Insider Ownership5.5%
Institutional Ownership101.9%
Short Float21.6%
% of All Funds Holding2.41%
Number of Funds Holding198

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$18.84Near-term / short-term trend
Weekly40-Week SMA$26.60Medium-term trend
Weekly80-Week SMA$19.93Cyclical trend (business cycle)
Weekly200-Week SMA$15.40Secular trend (multi-year)
Monthly10-Month SMA$29.55Near-term monthly trend
Monthly20-Month SMA$21.07Medium-term monthly trend
Monthly40-Month SMA$15.16Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$9.20 support 1.74x 1 months ago
$10.80 support 1.03x 12 months ago
$6.60 support 2.62x 16 months ago
$4.50 support 4.60x 21 months ago

Historical Earnings Reactions (48 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.56% 0.00% 47.92% 50.48% -17.66%
1 Day 1.20% 1.11% 58.33% 47.03% -27.02%
1 Week 0.95% -1.62% 44.68% 73.90% -23.26%
2 Weeks -0.24% -0.81% 46.81% 48.76% -29.02%
1 Month 1.36% 2.35% 59.57% 63.43% -38.53%

Next earnings: May 12, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-0.9%25.0%12
Feb3.3%50.0%12
Mar-4.6%30.8%13
Apr3.4%46.2%13
May4.3%66.7%12
Jun-0.9%41.7%12
Jul3.3%25.0%12
Aug0.6%50.0%12
Sep12.3%25.0%12
Oct6.0%50.0%12
Nov6.2%75.0%12
Dec12.5%25.0%12

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.19% 45.5% 578
Tuesday 0.29% 47.7% 635
Wednesday 0.38% 45.9% 632
Thursday 0.28% 50.8% 620
Friday 0.23% 46.8% 618

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 101.9%

Insider Transactions — Smart Summary

Total insider ownership: 5.5%

12-Month Insider Activity Summary

Total Filings26
Net Value-$11.1M
Net Shares Change15,156
% of Float0.0%
C-Suite Filings15
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
Kapusta Matthew C CEO, Managing Director -$770,091.09 3 3 sell
KLEMT CHRISTIAN Chief Financial Officer -$381,751.02 3 3 sell
Potts Jeannette Chief Legal Officer -$116,263.82 2 2 sell
Abi-Saab Walid Chief Medical Officer -$23,837.48 2 2 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-06-20 – 2025-07-01 9 9 -$322,426.12 2 C-suite
2026-02-27 – 2026-03-06 10 4 -$1.3M 10 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-03-06 Potts Jeannette Chief Legal Officer -$30,912.72 Transaction at $9.06, now +198.6%
2026-03-06 KLEMT CHRISTIAN Chief Financial Officer -$108,720 Transaction at $9.06, now +198.6%
2026-03-06 Abi-Saab Walid Chief Medical Officer -$7,320.48 Transaction at $9.06, now +198.6%
2026-03-06 Kapusta Matthew C CEO, Managing Director -$132,103.86 Transaction at $9.06, now +198.6%
2026-03-04 Potts Jeannette Chief Legal Officer -$85,351.1 Transaction at $9.95, now +171.9%
2026-03-04 Kapusta Matthew C CEO, Managing Director -$342,648.15 Transaction at $9.95, now +171.9%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Uniqure NV (QURE) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for QURE on Trend Edge →