Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge Setup Score
Trend Edge rates PRME Bullish with a Setup Score of 44, net conviction 25, actionability 79. How the Setup Score works →
Total Setup Score
44
Directional Bias
Bullish
Net Conviction
25
Actionability
79 (in range)
Key signals behind this score
Fresh Trend Turn — 40wk recapture 2w
80wk Uptrend — rising+above (sma 3.29 vs px 3.78)
200wk Uptrend — no SMA yet (neutral)
Funds Accumulating — momZ +0.86 · 2.06→2.13
About Prime Medicine, Inc. Common Stock
Prime Medicine, Inc., a biotechnology company, engages in delivering genetic medicines to address the spectrum of diseases by deploying gene editing technology in the United States. Its lead therapeutic product candidate is PM359 for Chronic Granulomatous Disease, which is in Phase 1/2 clinical trial; PM577 for Wilson Disease, that is in preclinical studies; and PM647 to treat genetic disorder caused by mutations in the SERPINA1 gene, resulting i… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: October 20, 2022
Headquarters: 60 First Street, Cambridge, MA, United States, 02141
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$3.28
Near-term / short-term trend
Weekly
40-Week SMA
$3.76
Medium-term trend
Weekly
80-Week SMA
$3.29
Cyclical trend (business cycle)
Weekly
200-Week SMA
$0.00
Secular trend (multi-year)
Monthly
10-Month SMA
$3.87
Near-term monthly trend
Monthly
20-Month SMA
$3.34
Medium-term monthly trend
Monthly
40-Month SMA
$5.72
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$4.90
resistance
1.16x
7 months ago
$3.20
support
1.39x
9 months ago
$2.50
support
2.93x
11 months ago
$1.20
support
1.81x
12 months ago
$6.60
resistance
1.44x
24 months ago
Historical Earnings Reactions (15 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
-0.30%
-0.48%
46.67%
7.22%
-7.65%
1 Day
-0.71%
-1.52%
40.00%
14.44%
-11.31%
1 Week
-1.94%
-5.94%
33.33%
34.22%
-30.79%
2 Weeks
-5.30%
-4.65%
33.33%
27.31%
-30.56%
1 Month
-2.71%
-6.81%
42.86%
40.82%
-30.56%
Next earnings: August 6, 2026 (25 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Prime Medicine, Inc. Common Stock
(PRME) powered by Claude Opus — Anthropic's most capable AI model.
The analysis covers five layers:
technical analysis (near-term, medium-term, cyclical, and secular trend, momentum,
volume shelf support and resistance, breakout and breakdown signals),
qualitative analysis (business model, competitive moat, sector dynamics),
insider sentiment (buy and sell signals from executive and director transactions),
share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and
fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit,
stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward.
Whether you are building a long position, initiating a short, or looking for a reversal setup,
AI Consult identifies the highest-probability signal from the current trend.