Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge Setup Score
Trend Edge rates PMN Bearish with a Setup Score of 27, net conviction 23, actionability 31. How the Setup Score works →
Total Setup Score
27
Directional Bias
Bearish
Net Conviction
23
Actionability
31 (in range)
Key signals behind this score
Fresh Breakdown — 40wk turn 10w · aligned 7w
80wk Downtrend — trend only (sma 13.91 vs px 14.25)
200wk Downtrend — falling+below (sma 49.97 vs px 14.25)
Short Attack — velZ +0.99 · age 20w×1.00 · 4.37%
Seasonal Headwind — july med -5.9% (mag 2/3) · posClose 31.58% (rel 2/3) · n19 ×1 = 11
About ProMIS Neurosciences Inc.
ProMIS Neurosciences, Inc. discovers and develops antibody therapies and therapeutic vaccines for neurodegenerative diseases and other misfolded protein diseases in Canada. The company's proprietary discovery platform comprises ProMIS, which enables drug discovery through a combination of protein biology, physics, and supercomputing. Its lead product candidates include PMN310, a monoclonal antibody (mAb) for toxic oligomers for treating Alzheimer… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: July 17, 2007
Headquarters: 1920 Yonge Street, Toronto, ON, Canada, M4S 3E2
Founder-Led: Yes — Neil Cashman (Chief Scientific Officer and Co-Founder)
Key Metrics
Current Price
$14.25
Market Cap
$128M
Float
4.6M
Shares Outstanding
9.0M
Price/Sales (TTM)
4,016.22
vs. Analyst Target
+144.5% to analyst PT
Revenue (TTM)
$7,558
Dividend Rate
None
Analyst Target Price
$34.84 (3 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$1,565
-$5.7M
-$3.2M
-$5.6M
2021
$8,138
-$12.0M
-$5.8M
-$9.3M
2022
$8,138.7
-$24.3M
-$15,070.3
-$23.9M
2023
N/A
-$17.5M
-$10.4M
-$17.8M
2024
N/A
$2.8M
N/A
$2.9M
2025
N/A
-$39.7M
N/A
-$39.7M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
N/A
-$10.1M
Sep 2025
N/A
-$11.6M
Dec 2025
N/A
-$10.7M
Mar 2026
N/A
-$8.2M
Ownership & Float
Insider Ownership
11.8%
Institutional Ownership
74.4%
Short Float
4.4%
% of All Funds Holding
0.27%
Number of Funds Holding
22
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$11.02
Near-term / short-term trend
Weekly
40-Week SMA
$11.79
Medium-term trend
Weekly
80-Week SMA
$13.91
Cyclical trend (business cycle)
Weekly
200-Week SMA
$49.97
Secular trend (multi-year)
Monthly
10-Month SMA
$12.37
Near-term monthly trend
Monthly
20-Month SMA
$14.47
Medium-term monthly trend
Monthly
40-Month SMA
$34.82
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$6.80
support
2.71x
5 months ago
Historical Earnings Reactions (54 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
0.16%
0.00%
22.22%
25.00%
-20.00%
1 Day
-0.31%
0.00%
20.37%
25.00%
-11.11%
1 Week
-1.09%
0.00%
37.04%
28.57%
-23.53%
2 Weeks
-4.19%
-4.63%
24.07%
75.00%
-46.67%
1 Month
-4.40%
-8.88%
26.42%
100.00%
-60.00%
Next earnings: August 12, 2026 (30 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
22.0%
47.4%
19
Feb
1.2%
35.0%
20
Mar
-5.8%
20.0%
20
Apr
14.7%
50.0%
20
May
-3.7%
30.0%
20
Jun
8.5%
35.0%
20
Jul
7.7%
31.6%
19
Aug
-6.5%
21.1%
19
Sep
-5.9%
31.6%
19
Oct
-4.9%
26.3%
19
Nov
-8.6%
31.6%
19
Dec
2.4%
36.8%
19
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.22%
19.2%
920
Tuesday
0.04%
20.5%
1007
Wednesday
0.44%
19.9%
1005
Thursday
-0.19%
17.5%
987
Friday
0.28%
20.3%
981
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 74.4%
Insider Transactions — Smart Summary
Total insider ownership: 11.8%
Founder-led management: Neil Cashman (Chief Scientific Officer and Co-Founder)
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The analysis covers five layers:
technical analysis (near-term, medium-term, cyclical, and secular trend, momentum,
volume shelf support and resistance, breakout and breakdown signals),
qualitative analysis (business model, competitive moat, sector dynamics),
insider sentiment (buy and sell signals from executive and director transactions),
share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and
fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit,
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Whether you are building a long position, initiating a short, or looking for a reversal setup,
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