PCVX — Vaxcyte Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates PCVX Bullish with a Setup Score of 37, net conviction 32, actionability 42. How the Setup Score works →

Total Setup Score37
Directional BiasBullish
Net Conviction32
Actionability42 (in range)

Key signals behind this score

About Vaxcyte Inc

Vaxcyte, Inc., a clinical-stage vaccine innovation company, develops conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent carrier-sparing investigational pneumococcal conjugate vaccine (PCV) for the prevention of invasive pneumococcal disease (IPD) in infants. The company also develops VAX-31, a 31-valent, carrier-sparing investigational PCV for the prevention of… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$61.09
Market Cap$9.13B
Float136.5M
Shares Outstanding148.8M
vs. Analyst Target+78.4% to analyst PT
Dividend RateNone
Analyst Target Price$109.00 (10 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 N/A -$89.2M -$1.4M -$87.8M
2021 N/A -$100M -$1.8M -$96.6M
2022 N/A -$223M -$9.2M -$214M
2023 N/A -$402M -$75.0M -$392M
2024 N/A -$464M -$15.8M -$448M
2025 N/A -$767M N/A -$742M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 N/A -$213M
Dec 2025 N/A -$247M
Mar 2026 N/A -$321M
Jun 2026 N/A -$284M

Ownership & Float

Insider Ownership0.5%
Institutional Ownership113.4%
Short Float10.6%
% of All Funds Holding3.76%
Number of Funds Holding331

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$57.79Near-term / short-term trend
Weekly40-Week SMA$53.95Medium-term trend
Weekly80-Week SMA$47.66Cyclical trend (business cycle)
Weekly200-Week SMA$57.79Secular trend (multi-year)
Monthly10-Month SMA$55.11Near-term monthly trend
Monthly20-Month SMA$49.85Medium-term monthly trend
Monthly40-Month SMA$59.66Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$52.00 support 1.27x 1 months ago
$36.30 support 1.06x 9 months ago
$30.90 support 1.14x 10 months ago
$73.00 resistance 1.57x 16 months ago
$94.00 resistance 1.15x 19 months ago

Historical Earnings Reactions (26 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -1.29% -0.78% 30.77% 6.53% -16.41%
1 Day 0.68% 1.53% 57.69% 15.36% -17.91%
1 Week 1.39% -1.81% 42.31% 34.34% -20.49%
2 Weeks 0.90% 2.12% 53.85% 22.49% -20.08%
1 Month 1.39% -0.65% 48.00% 55.93% -18.30%

Next earnings: October 24, 2026 (58 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.48% 54.1% 292
Tuesday -0.10% 47.2% 322
Wednesday 0.17% 50.0% 320
Thursday 0.05% 48.7% 312
Friday 0.12% 50.3% 310

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 113.4%

Insider Transactions — Smart Summary

Total insider ownership: 0.5%

Founder-led management: Grant Pickering (Chief Executive Officer), Jeff Fairman (Vice President of Research)

12-Month Insider Activity Summary

Total Filings18
Net Value-$8.0M
Net Shares Change-92,080
% of Float-0.1%
C-Suite Filings18
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
PICKERING GRANT CHIEF EXECUTIVE OFFICER -$3.6M 3 N/A
Dhaliwal Harpreet S. Chief Technical Ops Officer -$968,528.927 2 1 sell
Cowan Elvia SVP, FINANCE -$662,118.789 2 1 sell
Wassil Jim CHIEF OPERATING OFFICER -$602,434.185 2 N/A
GUGGENHIME ANDREW PRESIDENT AND CFO -$485,379 1 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2026-07-28 – 2026-08-05 4 4 -$2.1M 4 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-01-02 Dhaliwal Harpreet S. Chief Technical Ops Officer -$454,890.927 Transaction at $46.69, now +30.8%
2025-12-29 Cowan Elvia SVP, FINANCE -$556,971.835 Transaction at $47.92, now +27.5%
2026-06-26 PICKERING GRANT CHIEF EXECUTIVE OFFICER -$1.3M Transaction at $55.22, now +10.6%
2026-06-18 PICKERING GRANT CHIEF EXECUTIVE OFFICER -$1.3M Transaction at $35.60, now +71.6%
2026-03-18 Cowan Elvia SVP, Finance & CAO -$105,146.954 Transaction at $55.57, now +9.9%
2026-03-11 Wassil Jim CHIEF OPERATING OFFICER -$493,276.785 Transaction at $59.10, now +3.4%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Vaxcyte Inc (PCVX) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for PCVX on Trend Edge →