OMER — Omeros Corporation

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Omeros Corporation

Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory di… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$11.15
Market Cap$896M
Float69.8M
Shares Outstanding72.4M
P/E (Forward)65.36
P/E (TTM)10.86
Price/Sales (TTM)87.50
vs. Analyst Target+200.4% to analyst PT
Profit Margin871.02%
Operating Margin (TTM)-176.09%
Revenue (TTM)$9.9M
Dividend RateNone
Analyst Target Price$33.50 (4 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $73.8M -$138M -$1.6M -$168M
2021 $90.5M -$111M -$1.4M -$170M
2022 N/A $47.4M -$952,000 -$158M
2023 N/A -$118M -$69.8M -$143M
2024 N/A -$157M -$950,000 -$157M
2025 N/A -$3.4M N/A -$122M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$25.4M
Sep 2025 N/A -$30.9M
Dec 2025 N/A $86.5M
Mar 2026 $9.9M $56.1M

Ownership & Float

Insider Ownership3.6%
Institutional Ownership44.4%
Short Float22.6%
% of All Funds Holding1.79%
Number of Funds Holding147

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$12.33Near-term / short-term trend
Weekly40-Week SMA$10.02Medium-term trend
Weekly80-Week SMA$8.43Cyclical trend (business cycle)
Weekly200-Week SMA$5.70Secular trend (multi-year)
Monthly10-Month SMA$10.25Near-term monthly trend
Monthly20-Month SMA$8.52Medium-term monthly trend
Monthly40-Month SMA$6.22Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$17.50 resistance 1.13x 3 months ago
$9.90 support 1.72x 4 months ago
$4.10 support 5.02x 6 months ago
$3.00 support 1.61x 9 months ago

Historical Earnings Reactions (67 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.40% 0.33% 55.22% 14.38% -24.94%
1 Day 1.86% -1.47% 43.28% 65.87% -25.47%
1 Week 2.91% 1.24% 58.21% 84.49% -37.10%
2 Weeks 2.51% -0.72% 47.76% 170.88% -44.70%
1 Month 3.45% -1.92% 46.27% 126.19% -45.54%

Next earnings: August 1, 2026 (64 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-1.3%35.3%17
Feb5.7%58.8%17
Mar8.4%58.8%17
Apr-0.7%41.2%17
May-3.2%37.5%16
Jun3.6%31.3%16
Jul6.5%43.8%16
Aug-2.9%31.3%16
Sep-0.2%31.3%16
Oct-4.2%50.0%16
Nov23.6%64.7%17
Dec6.6%52.9%17

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.01% 46.7% 783
Tuesday 0.26% 48.3% 861
Wednesday 0.47% 49.9% 857
Thursday 0.01% 45.4% 841
Friday 0.11% 46.0% 839

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 44.4%

Insider Transactions — Smart Summary

Total insider ownership: 3.6%

Founder-led management: Gregory A. Demopulos (Chief Executive Officer & President), George A. Gaitanaris (Chief Scientific Officer)

12-Month Insider Activity Summary

Total Filings1
Net Value-$659,112
Net Shares Change-30,000
% of Float-0.0%
C-Suite Filings1
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
Borges David J. VP, Finance and CAO -$659,112 1 1 sell

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-01-14 Borges David J. VP, Finance and CAO -$659,112 Transaction at $7.79, now +43.2%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Omeros Corporation (OMER) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for OMER on Trend Edge →