Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases. The company's lead products candidate is the Narsoplimab (OMS721/MASP-2) for the treatment of hematopoietic stem-cell transplant-associated thrombotic microangiopathy (TA-TMA); and in Phase II clinical trial to treat COVID-19 and acute respiratory di… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: October 8, 2009
Headquarters: The Omeros Building, Seattle, WA, United States, 98119
Founder-Led: Yes — Gregory A. Demopulos (Chief Executive Officer & President), George A. Gaitanaris (Chief Scientific Officer)
Key Metrics
Current Price
$10.01
Market Cap
$743M
Float
69.8M
Shares Outstanding
72.4M
P/E (Forward)
58.14
P/E (TTM)
9.01
Price/Sales (TTM)
75.13
vs. Analyst Target
+229.7% to analyst PT
Profit Margin
871.02%
Operating Margin (TTM)
-176.09%
Revenue (TTM)
$9.9M
Dividend Rate
None
Analyst Target Price
$33.00 (4 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$73.8M
-$138M
-$1.6M
-$168M
2021
$90.5M
-$111M
-$1.4M
-$170M
2022
N/A
$47.4M
-$952,000
-$158M
2023
N/A
-$118M
-$69.8M
-$143M
2024
N/A
-$157M
-$950,000
-$157M
2025
N/A
-$3.4M
N/A
-$122M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
N/A
-$25.4M
Sep 2025
N/A
-$30.9M
Dec 2025
N/A
$86.5M
Mar 2026
$9.9M
$56.1M
Ownership & Float
Insider Ownership
3.6%
Institutional Ownership
44.6%
Short Float
25.9%
% of All Funds Holding
1.79%
Number of Funds Holding
147
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$10.18
Near-term / short-term trend
Weekly
40-Week SMA
$10.94
Medium-term trend
Weekly
80-Week SMA
$8.33
Cyclical trend (business cycle)
Weekly
200-Week SMA
$5.85
Secular trend (multi-year)
Monthly
10-Month SMA
$11.37
Near-term monthly trend
Monthly
20-Month SMA
$8.72
Medium-term monthly trend
Monthly
40-Month SMA
$6.50
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$17.50
resistance
1.13x
5 months ago
$4.10
support
5.02x
8 months ago
$3.00
support
1.61x
11 months ago
Historical Earnings Reactions (67 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
0.40%
0.33%
55.22%
14.38%
-24.94%
1 Day
1.86%
-1.47%
43.28%
65.87%
-25.47%
1 Week
2.91%
1.24%
58.21%
84.49%
-37.10%
2 Weeks
2.51%
-0.72%
47.76%
170.88%
-44.70%
1 Month
3.45%
-1.92%
46.27%
126.19%
-45.54%
Next earnings: August 13, 2026 (30 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
-1.3%
35.3%
17
Feb
5.7%
58.8%
17
Mar
8.4%
58.8%
17
Apr
-0.7%
41.2%
17
May
-4.5%
35.3%
17
Jun
2.6%
29.4%
17
Jul
6.5%
43.8%
16
Aug
-2.9%
31.3%
16
Sep
-0.2%
31.3%
16
Oct
-4.2%
50.0%
16
Nov
23.6%
64.7%
17
Dec
6.6%
52.9%
17
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.05%
47.0%
789
Tuesday
0.26%
48.3%
867
Wednesday
0.46%
49.9%
864
Thursday
0.02%
45.6%
848
Friday
0.06%
45.9%
844
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 44.6%
Insider Transactions — Smart Summary
Total insider ownership: 3.6%
Founder-led management: Gregory A. Demopulos (Chief Executive Officer & President), George A. Gaitanaris (Chief Scientific Officer)
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Omeros Corporation
(OMER) powered by Claude Opus — Anthropic's most capable AI model.
The analysis covers five layers:
technical analysis (near-term, medium-term, cyclical, and secular trend, momentum,
volume shelf support and resistance, breakout and breakdown signals),
qualitative analysis (business model, competitive moat, sector dynamics),
insider sentiment (buy and sell signals from executive and director transactions),
share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and
fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit,
stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward.
Whether you are building a long position, initiating a short, or looking for a reversal setup,
AI Consult identifies the highest-probability signal from the current trend.