NUVB — Nuvation Bio Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Nuvation Bio Inc

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$4.72
Market Cap$1.54B
Float237.6M
Shares Outstanding347.2M
Price/Sales (TTM)10.73
vs. Analyst Target+161.3% to analyst PT
Profit Margin-102.06%
Operating Margin (TTM)4.66%
Revenue (TTM)$143M
Dividend RateNone
Analyst Target Price$12.33 (7 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 N/A -$41.7M -$103,000 -$41.6M
2021 N/A -$86.8M -$368,000 -$93.1M
2022 N/A -$104M -$484,000 -$120M
2023 N/A -$75.8M -$222,000 -$75.6M
2024 $7.9M -$568M $795,000 -$567M
2025 $62.9M -$205M $54.5M -$191M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $4.8M -$59.0M
Sep 2025 $13.1M -$55.8M
Dec 2025 $41.9M -$36.6M
Mar 2026 $83.2M $5.4M

Ownership & Float

Insider Ownership18.6%
Institutional Ownership64.8%
Short Float21.3%
% of All Funds Holding2.53%
Number of Funds Holding208

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$4.58Near-term / short-term trend
Weekly40-Week SMA$5.29Medium-term trend
Weekly80-Week SMA$3.80Cyclical trend (business cycle)
Weekly200-Week SMA$2.81Secular trend (multi-year)
Monthly10-Month SMA$5.35Near-term monthly trend
Monthly20-Month SMA$3.80Medium-term monthly trend
Monthly40-Month SMA$2.97Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$3.80 support 1.80x 6 months ago
$3.00 support 1.81x 7 months ago
$2.30 support 1.22x 8 months ago
$2.00 support 1.51x 9 months ago
$1.80 support 1.51x 12 months ago

Historical Earnings Reactions (23 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 1.03% 0.00% 47.83% 8.82% -4.82%
1 Day 2.04% 2.44% 65.22% 19.25% -8.03%
1 Week 3.89% 1.22% 65.22% 30.48% -17.18%
2 Weeks -0.74% -0.65% 43.48% 23.93% -25.83%
1 Month 7.04% 2.73% 54.55% 94.12% -18.81%

Next earnings: May 19, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.06% 43.3% 268
Tuesday 0.22% 50.2% 297
Wednesday 0.32% 45.4% 295
Thursday -0.24% 45.5% 288
Friday -0.04% 44.6% 289

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 64.8%

Insider Transactions — Smart Summary

Total insider ownership: 18.6%

Founder-led management: David Hung (Founder, President, CEO & Chairman)

12-Month Insider Activity Summary

Total Filings15
Net Value-$4.0M
Net Shares Change617,300
% of Float0.3%
C-Suite Filings15
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
Hattersley Gary CHIEF SCIENTIFIC OFFICER -$2.0M 1 1 sell
Hanley David C. CHIEF TECHNICAL OPERATIONS -$1.1M 1 1 sell
Liu Dongfang CHIEF MEDICAL OFFICER -$919,229 3 3 sell
Hung David PRESIDENT AND CEO +$893,500 1 1 buy
Sjogren Colleen Chief Commercial Officer +$90,350 1 1 buy
Wentworth Kerry CHIEF REGULATORY OFFICER +$89,740 1 1 buy
Markel Stacy CHIEF PEOPLE OFFICER +$17,100 1 1 buy
Sauvage Philippe Chief Financial Officer +$13,215.19 1 1 buy

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-06-18 – 2025-06-18 5 5 +$1.1M 5 C-suite
2025-11-19 – 2025-12-03 6 3 -$4.0M 6 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-06-18 Wentworth Kerry CHIEF REGULATORY OFFICER +$89,740 Transaction at $1.79, now +163.0%
2025-06-18 Sjogren Colleen Chief Commercial Officer +$90,350 Transaction at $1.81, now +161.2%
2025-06-18 Sauvage Philippe Chief Financial Officer +$13,215.19 Transaction at $1.81, now +160.7%
2025-06-18 Markel Stacy CHIEF PEOPLE OFFICER +$17,100 Transaction at $1.71, now +176.0%
2025-06-18 Hung David PRESIDENT AND CEO +$893,500 Transaction at $1.79, now +164.1%
2025-12-03 Liu Dongfang CHIEF MEDICAL OFFICER -$733,755 Transaction at $5.38, now -12.2%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Nuvation Bio Inc (NUVB) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for NUVB on Trend Edge →