NUVB — Nuvation Bio Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates NUVB Bullish with a Setup Score of 49, net conviction 68, actionability 36. How the Setup Score works →

Total Setup Score49
Directional BiasBullish
Net Conviction68
Actionability36 (in range)

Key signals behind this score

About Nuvation Bio Inc

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on developing product candidates for cancer treatment. The company's lead product candidate is IBTROZI (taletrectinib), a ROS1 inhibitor for the treatment of patients with ROS1+ non-small cell lung cancer. It is also developing Safusidenib, an inhibitor of mutant isocitrate dehydrogenase 1 in phase 3 clinical trials for the maintenance treatment of high-risk or high-grade IDH1… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$6.76
Market Cap$2.40B
Float263.6M
Shares Outstanding350.1M
Price/Sales (TTM)14.12
vs. Analyst Target+93.8% to analyst PT
Profit Margin-88.19%
Operating Margin (TTM)-161.06%
Revenue (TTM)$170M
Dividend RateNone
Analyst Target Price$13.10 (7 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 N/A -$41.7M -$103,000 -$41.6M
2021 N/A -$86.8M -$368,000 -$86.7M
2022 N/A -$104M -$484,000 -$104M
2023 N/A -$75.8M -$222,000 -$75.6M
2024 $7.9M -$568M $795,000 -$567M
2025 $62.9M -$205M $54.5M -$189M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $13.1M -$55.8M
Dec 2025 $41.9M -$36.6M
Mar 2026 $83.2M $5.4M
Jun 2026 $31.7M -$62.8M

Ownership & Float

Insider Ownership18.4%
Institutional Ownership67.9%
Short Float20.3%
% of All Funds Holding2.74%
Number of Funds Holding241

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$6.22Near-term / short-term trend
Weekly40-Week SMA$5.93Medium-term trend
Weekly80-Week SMA$4.37Cyclical trend (business cycle)
Weekly200-Week SMA$3.05Secular trend (multi-year)
Monthly10-Month SMA$6.04Near-term monthly trend
Monthly20-Month SMA$4.35Medium-term monthly trend
Monthly40-Month SMA$3.31Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$3.80 support 1.80x 9 months ago
$3.00 support 1.81x 10 months ago
$2.30 support 1.22x 11 months ago
$1.80 support 1.51x 15 months ago

Historical Earnings Reactions (24 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 1.12% 0.06% 50.00% 8.82% -4.82%
1 Day 2.29% 2.69% 66.67% 19.25% -8.03%
1 Week 3.80% 1.51% 66.67% 30.48% -17.18%
2 Weeks -0.15% -0.32% 45.83% 23.93% -25.83%
1 Month 7.14% 3.13% 56.52% 94.12% -18.81%

Next earnings: October 25, 2026 (61 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.02% 43.6% 280
Tuesday 0.28% 51.1% 311
Wednesday 0.34% 46.0% 309
Thursday -0.22% 46.0% 302
Friday -0.05% 44.9% 301

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 67.9%

Insider Transactions — Smart Summary

Total insider ownership: 18.4%

Founder-led management: David Hung (Founder, President, CEO & Chairman)

12-Month Insider Activity Summary

Total Filings15
Net Value-$6.5M
Net Shares Change25,000
% of Float0.0%
C-Suite Filings14
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
Hattersley Gary CHIEF SCIENTIFIC OFFICER -$2.5M 2 1 sell
Hanley David C. CHIEF TECHNICAL OPERATIONS -$1.1M 1 1 sell
Liu Dongfang CHIEF MEDICAL OFFICER -$1.0M 4 4 sell
Wentworth Kerry CHIEF REGULATORY OFFICER -$194,600.7 1 N/A
Sauvage Philippe Chief Financial Officer -$182,930.717 1 N/A
Mashal Robert +$118,250 1 1 buy

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-11-19 – 2025-12-03 6 3 -$4.0M 6 C-suite
2026-06-11 – 2026-06-24 4 4 -$783,218.917 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-06-11 Mashal Robert +$118,250 Transaction at $4.73, now +42.9%
2025-11-24 Hattersley Gary CHIEF SCIENTIFIC OFFICER -$2.0M Transaction at $4.56, now +48.1%
2025-11-21 Hanley David C. CHIEF TECHNICAL OPERATIONS -$1.1M Transaction at $4.50, now +50.1%
2025-12-03 Liu Dongfang CHIEF MEDICAL OFFICER -$733,755 Transaction at $5.38, now +25.7%
2025-11-26 Liu Dongfang CHIEF MEDICAL OFFICER -$82,800 Transaction at $5.68, now +19.0%
2025-11-24 Liu Dongfang CHIEF MEDICAL OFFICER -$102,674 Transaction at $4.44, now +52.4%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Nuvation Bio Inc (NUVB) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for NUVB on Trend Edge →