NTLA — Intellia Therapeutics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates NTLA Bearish with a Setup Score of 28, net conviction 23, actionability 34. How the Setup Score works →

Total Setup Score28
Directional BiasBearish
Net Conviction23
Actionability34 (in range)

Key signals behind this score

About Intellia Therapeutics Inc

Intellia Therapeutics, Inc. operates as a clinical-stage genome editing company focused on developing potentially curative therapeutics using CRISPR/Cas9-based technologies. The company offers clustered, regularly interspaced short palindromic repeats ("CRISPR")/CRISPR associated 9 ("Cas9") technology for genome editing. The company provides a modular platform, to advance in vivo and ex vivo therapies for diseases. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$13.19
Market Cap$1.74B
Float134.4M
Shares Outstanding140.1M
Price/Sales (TTM)29.29
vs. Analyst Target+81.5% to analyst PT
Operating Margin (TTM)-1472.26%
Revenue (TTM)$59.5M
Dividend RateNone
Analyst Target Price$23.94 (29 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $58.0M -$126M $58.0M -$130M
2021 $33.1M -$260M $33.1M -$261M
2022 $52.1M -$474M $44.5M -$467M
2023 $36.3M -$481M $27.3M -$472M
2024 $57.9M -$519M $47.6M -$509M
2025 $67.7M -$413M $51.7M -$397M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $13.8M -$101M
Dec 2025 $23.0M -$95.8M
Mar 2026 $15.0M -$96.2M
Jun 2026 $7.7M -$107M

Ownership & Float

Insider Ownership3.9%
Institutional Ownership99.9%
Short Float32.7%
% of All Funds Holding3.72%
Number of Funds Holding327

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$13.11Near-term / short-term trend
Weekly40-Week SMA$12.59Medium-term trend
Weekly80-Week SMA$12.01Cyclical trend (business cycle)
Weekly200-Week SMA$22.52Secular trend (multi-year)
Monthly10-Month SMA$12.61Near-term monthly trend
Monthly20-Month SMA$11.58Medium-term monthly trend
Monthly40-Month SMA$19.14Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$9.30 support 1.15x 6 months ago
$17.30 resistance 2.21x 9 months ago
$7.00 support 1.49x 13 months ago
$20.50 resistance 1.77x 21 months ago

Historical Earnings Reactions (42 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.10% 0.42% 64.29% 7.98% -25.77%
1 Day -0.94% -1.47% 40.48% 14.33% -22.73%
1 Week -0.38% 0.17% 50.00% 29.38% -37.31%
2 Weeks -0.56% -3.74% 40.48% 53.77% -37.18%
1 Month 1.11% -3.19% 39.02% 71.03% -33.99%

Next earnings: October 25, 2026 (59 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan4.7%50.0%10
Feb6.5%70.0%10
Mar-6.9%20.0%10
Apr-2.9%50.0%10
May0.6%30.0%10
Jun22.7%90.9%11
Jul0.7%54.5%11
Aug2.1%50.0%10
Sep-1.1%20.0%10
Oct-10.6%20.0%10
Nov7.8%60.0%10
Dec-8.4%30.0%10

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.46% 51.9% 484
Tuesday 0.06% 49.3% 533
Wednesday 0.19% 50.0% 530
Thursday -0.14% 48.2% 521
Friday -0.05% 48.5% 520

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 99.9%

Insider Transactions — Smart Summary

Total insider ownership: 3.9%

12-Month Insider Activity Summary

Total Filings17
Net Value-$1.8M
Net Shares Change48,142
% of Float0.0%
C-Suite Filings16
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
Cohen Fred E +$1.4M 1 1 buy
Dulac Edward J III EVP, Chief Financial Officer -$149,999.34 2 2 sell
Lebwohl David EVP, Chief Medical Officer -$109,626.63 1 1 sell
Clark Eliana EVP, Chief Technical Officer -$95,997.61 2 2 sell
Schultes Birgit C EVP, Chief Scientific Officer -$78,358.68 1 1 sell
Dube Michael P VP, Chief Accounting Officer -$71,844.67 2 2 sell
BASTA JAMES EVP, General Counsel -$16,687.58 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2026-01-07 – 2026-01-07 8 8 +$630,361.23 7 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-07-24 Dulac Edward J III EVP, Chief Financial Officer -$91,248.75 Transaction at $11.25, now +17.2%
2026-07-06 Dube Michael P VP, Chief Accounting Officer -$44,315.98 Transaction at $16.78, now -21.4%
2026-03-03 BASTA JAMES EVP, General Counsel -$16,687.58 Transaction at $13.78, now -4.3%
2026-01-07 Cohen Fred E +$1.4M Transaction at $9.35, now +41.1%
2026-03-03 Clark Eliana EVP, Chief Technical Officer -$8,364.46 Transaction at $13.78, now -4.3%
2026-01-07 Schultes Birgit C EVP, Chief Scientific Officer -$78,358.68 Transaction at $9.21, now +43.2%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Intellia Therapeutics Inc (NTLA) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for NTLA on Trend Edge →