MNPR — Monopar Therapeutics Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Monopar Therapeutics Inc

Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. The company develops ALXN1840, a late-stage, investigational once-daily and oral medicine; MNPR-101, a proprietary humanized monoclonal antibody that is conjugated with different radioisotopes for the treatment of advanced solid tumors expressing urokinase plasminogen activator receptor; and M… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$64.55
Market Cap$435M
Float4.1M
Shares Outstanding6.7M
vs. Analyst Target+74.5% to analyst PT
Dividend RateNone
Analyst Target Price$112.62 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $122,400 -$6.3M $122,400 -$6.3M
2021 N/A -$9.1M N/A -$9.1M
2022 N/A -$10.5M N/A -$10.5M
2023 N/A -$8.4M N/A -$8.8M
2024 N/A -$15.6M N/A -$16.2M
2025 N/A -$13.7M N/A -$16.7M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$2.5M
Sep 2025 N/A -$3.4M
Dec 2025 N/A -$5.2M
Mar 2026 N/A -$3.9M

Ownership & Float

Insider Ownership23.2%
Institutional Ownership93.3%
Short Float40.5%
% of All Funds Holding0.89%
Number of Funds Holding73

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$57.85Near-term / short-term trend
Weekly40-Week SMA$66.03Medium-term trend
Weekly80-Week SMA$50.37Cyclical trend (business cycle)
Weekly200-Week SMA$24.02Secular trend (multi-year)
Monthly10-Month SMA$64.01Near-term monthly trend
Monthly20-Month SMA$48.26Medium-term monthly trend
Monthly40-Month SMA$26.25Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$84.00 resistance 3.49x 4 months ago
$32.80 support 1.34x 7 months ago
$6.70 support 1.92x 18 months ago
$2.60 support 3.93x 19 months ago

Historical Earnings Reactions (27 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.52% -0.20% 40.74% 8.48% -11.25%
1 Day -1.98% -2.78% 33.33% 9.73% -14.24%
1 Week -6.02% -2.86% 33.33% 16.76% -49.40%
2 Weeks -4.45% -2.43% 38.46% 21.62% -53.04%
1 Month 1.16% -2.51% 42.31% 78.73% -58.50%

Next earnings: August 2, 2026 (66 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.57% 40.5% 301
Tuesday 0.24% 46.0% 335
Wednesday 0.44% 49.7% 330
Thursday 2.51% 46.9% 324
Friday -0.42% 44.4% 324

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 93.3%

Insider Transactions — Smart Summary

Total insider ownership: 23.2%

Founder-led management: Chandler Drew Robinson (Chief Executive Officer), Christopher M. Starr (Executive Chairman of the Board)

12-Month Insider Activity Summary

Total Filings6
Net Value-$35.6M
Net Shares Change-553,850
% of Float-13.4%
C-Suite Filings3
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
Tactic Pharma LLC Chief Executive Officer -$35.0M 1 1 sell
Robinson Chandler Chief Executive Officer -$671,936.16 1 1 sell
STARR CHRISTOPHER M -$671,936.16 1 1 sell
Tsuchimoto Kim R -$356,126.165 1 1 sell
KLAUSNER ARTHUR J -$343,888.977 1 1 sell
Vu Quan Anh Chief Financial Officer +$104,925 1 1 buy

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-07-16 – 2025-07-16 3 3 -$1.7M 1 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-12-29 Vu Quan Anh Chief Financial Officer +$104,925 Transaction at $69.95, now -7.7%
2025-12-19 KLAUSNER ARTHUR J -$343,888.977 Transaction at $67.15, now -3.9%
2025-09-26 Tactic Pharma LLC Chief Executive Officer -$35.0M Transaction at $63.61, now +1.5%
2025-07-16 Robinson Chandler Chief Executive Officer -$671,936.16 Transaction at $20.00, now +222.7%
2025-07-16 Tsuchimoto Kim R -$356,126.165 Transaction at $20.00, now +222.7%
2025-07-16 STARR CHRISTOPHER M -$671,936.16 Transaction at $20.00, now +222.7%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Monopar Therapeutics Inc (MNPR) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for MNPR on Trend Edge →