MIRM — Mirum Pharmaceuticals Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates MIRM Bullish with a Setup Score of 0, net conviction 60, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBullish
Net Conviction60
Actionability0 (extended)

Key signals behind this score

About Mirum Pharmaceuticals Inc

Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$122.13
Market Cap$7.79B
Float52.5M
Shares Outstanding61.0M
P/E (Forward)2,000.00
Price/Sales (TTM)13.67
vs. Analyst Target+20.0% to analyst PT
Profit Margin-140.24%
Operating Margin (TTM)-39.51%
Revenue (TTM)$570M
Dividend RateNone
Analyst Target Price$146.50 (10 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $11.0M -$103M -$623,000 -$102M
2021 $19.1M -$84.0M $17.2M -$65.4M
2022 $77.1M -$136M $64.7M -$123M
2023 $186M -$163M $139M -$136M
2024 $337M -$87.9M $255M -$49.0M
2025 $521M -$23.4M $421M $17.2M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $128M -$5.9M
Sep 2025 $133M $2.9M
Dec 2025 $149M -$5.7M
Mar 2026 $160M -$790M

Ownership & Float

Insider Ownership1.4%
Institutional Ownership114.4%
Short Float13.2%
% of All Funds Holding3.53%
Number of Funds Holding290

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$108.09Near-term / short-term trend
Weekly40-Week SMA$90.68Medium-term trend
Weekly80-Week SMA$71.49Cyclical trend (business cycle)
Weekly200-Week SMA$46.02Secular trend (multi-year)
Monthly10-Month SMA$95.06Near-term monthly trend
Monthly20-Month SMA$73.55Medium-term monthly trend
Monthly40-Month SMA$52.35Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$100.00 support 1.27x 0 months ago
$80.00 support 1.33x 5 months ago
$52.00 support 1.91x 10 months ago
$45.00 support 1.03x 12 months ago
$34.50 support 1.25x 23 months ago

Historical Earnings Reactions (28 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 1.77% 0.89% 67.86% 9.02% -2.96%
1 Day 2.90% 2.46% 67.86% 16.22% -6.50%
1 Week 1.79% 1.37% 57.14% 21.43% -19.88%
2 Weeks 4.00% 1.98% 60.71% 29.56% -25.94%
1 Month 8.30% 6.28% 62.96% 45.51% -25.42%

Next earnings: August 5, 2026 (24 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan6.6%71.4%7
Feb3.8%71.4%7
Mar-4.3%42.9%7
Apr5.8%57.1%7
May-2.5%28.6%7
Jun10.6%71.4%7
Jul7.6%66.7%6
Aug10.8%71.4%7
Sep-4.4%28.6%7
Oct-10.8%14.3%7
Nov8.5%71.4%7
Dec31.5%57.1%7

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.38% 50.9% 328
Tuesday 0.03% 53.6% 362
Wednesday 0.04% 49.2% 358
Thursday 0.26% 50.4% 351
Friday 0.41% 52.6% 350

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 114.4%

Insider Transactions — Smart Summary

Total insider ownership: 1.4%

Founder-led management: Christopher Peetz (Chief Executive Officer)

12-Month Insider Activity Summary

Total Filings42
Net Value-$23.1M
Net Shares Change353,200
% of Float0.7%
C-Suite Filings28
Clusters Detected5

Key Insiders

NameTitleNet ValueFilingsActivity
Heron Patrick J +$9.0M 1 1 buy
Peetz Christopher CHIEF EXECUTIVE OFFICER -$3.8M 1 1 sell
Radovich Peter PRESIDENT AND COO -$2.1M 3 3 sell
Quan Joanne CHIEF MEDICAL OFFICER -$1.5M 3 3 sell
BJERKHOLT ERIC CHIEF FINANCIAL OFFICER -$670,242.957 1 1 sell
Howe Jolanda SVP, GLOBAL CONTROLLER -$435,239.423 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-08 – 2025-08-12 4 3 -$4.9M 4 C-suite
2026-01-15 – 2026-01-27 12 7 +$5.8M 10 C-suite
2026-02-03 – 2026-02-17 4 4 -$1.5M 3 C-suite
2026-03-17 – 2026-03-17 6 6 -$7.2M 5 C-suite
2026-06-02 – 2026-06-09 3 3 -$3.6M 2 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-01-27 Heron Patrick J +$9.0M Transaction at $68.48, now +78.3%
2026-03-17 Radovich Peter PRESIDENT AND COO -$1.5M Transaction at $91.98, now +32.8%
2026-03-17 Peetz Christopher CHIEF EXECUTIVE OFFICER -$3.8M Transaction at $91.98, now +32.8%
2026-03-17 Quan Joanne CHIEF MEDICAL OFFICER -$670,242.957 Transaction at $91.98, now +32.8%
2026-03-17 Howe Jolanda SVP, GLOBAL CONTROLLER -$435,239.423 Transaction at $91.98, now +32.8%
2026-03-17 BJERKHOLT ERIC CHIEF FINANCIAL OFFICER -$670,242.957 Transaction at $91.98, now +32.8%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Mirum Pharmaceuticals Inc (MIRM) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for MIRM on Trend Edge →