MGTX — MeiraGTx Holdings PLC

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About MeiraGTx Holdings PLC

MeiraGTx Holdings plc, a clinical-stage genetic medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also develops AAV-AQP1 for radiation-induced grade 2/3 radiation-induced xerostomia, as well as for Sjogren's syndrome; AAV-GA… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$9.24
Market Cap$887M
Float52.3M
Shares Outstanding92.6M
P/E (Forward)1.61
Price/Sales (TTM)11.12
vs. Analyst Target+205.7% to analyst PT
Profit Margin-151.12%
Operating Margin (TTM)-13930.72%
Revenue (TTM)$79.8M
Dividend RateNone
Analyst Target Price$28.25 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $15.6M -$58.0M $15.6M -$53.7M
2021 $37.7M -$79.6M $37.7M -$71.4M
2022 $15.9M -$130M $15.9M -$116M
2023 $14.0M -$84.0M $14.0M -$57.1M
2024 $33.3M -$148M $9.5M -$122M
2025 $81.4M -$114M $76.5M -$106M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $3.7M -$38.8M
Sep 2025 $410,000 -$50.5M
Dec 2025 $75.4M $15.1M
Mar 2026 $293,000 -$46.3M

Ownership & Float

Insider Ownership17.9%
Institutional Ownership60.5%
Short Float11.0%
% of All Funds Holding1.48%
Number of Funds Holding122

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$9.02Near-term / short-term trend
Weekly40-Week SMA$8.17Medium-term trend
Weekly80-Week SMA$7.40Cyclical trend (business cycle)
Weekly200-Week SMA$6.62Secular trend (multi-year)
Monthly10-Month SMA$8.32Near-term monthly trend
Monthly20-Month SMA$7.41Medium-term monthly trend
Monthly40-Month SMA$6.50Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$7.40 support 1.24x 1 months ago
$6.50 support 1.48x 9 months ago
$5.20 support 1.02x 10 months ago
$4.20 support 2.01x 18 months ago

Historical Earnings Reactions (33 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.23% 0.33% 54.55% 3.76% -11.73%
1 Day -0.93% -0.74% 42.42% 7.63% -14.04%
1 Week -0.53% -2.64% 42.42% 29.67% -25.74%
2 Weeks -0.38% -2.12% 43.75% 34.15% -20.80%
1 Month -1.64% -6.00% 34.38% 42.28% -33.94%

Next earnings: August 2, 2026 (67 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-1.2%37.5%8
Feb3.3%50.0%8
Mar-5.3%25.0%8
Apr-1.4%75.0%8
May-0.7%57.1%7
Jun2.9%42.9%7
Jul2.6%62.5%8
Aug-4.6%37.5%8
Sep-0.3%75.0%8
Oct8.8%37.5%8
Nov5.1%62.5%8
Dec5.4%62.5%8

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.25% 48.9% 376
Tuesday 0.12% 47.7% 411
Wednesday 0.13% 48.2% 407
Thursday -0.20% 42.8% 400
Friday 0.02% 47.6% 401

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 60.5%

Insider Transactions — Smart Summary

Total insider ownership: 17.9%

12-Month Insider Activity Summary

Total Filings9
Net Value-$3.1M
Net Shares Change-2,650,661
% of Float-5.1%
C-Suite Filings8
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
PERCEPTIVE ADVISORS LLC -$18.2M 1 1 sell
Forbes Alexandria PRESIDENT and CEO -$1.8M 4 N/A
Giroux Richard CFO and COO -$989,680 3 N/A
Naylor Stuart CHIEF DEV. OFFICER -$258,906.96 1 N/A

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-01-02 PERCEPTIVE ADVISORS LLC -$18.2M Transaction at $7.91, now +16.8%
2026-05-19 Forbes Alexandria PRESIDENT and CEO -$568,540 Transaction at $9.17, now +0.8%
2026-04-21 Giroux Richard CFO and COO -$572,320 Transaction at $10.22, now -9.6%
2026-04-07 Naylor Stuart CHIEF DEV. OFFICER -$258,906.96 Transaction at $9.36, now -1.3%
2026-03-24 Forbes Alexandria PRESIDENT and CEO -$459,420 Transaction at $7.41, now +24.7%
2025-10-21 Giroux Richard CFO and COO -$212,880 Transaction at $8.87, now +4.2%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for MeiraGTx Holdings PLC (MGTX) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for MGTX on Trend Edge →