Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge Setup Score
Trend Edge rates MGNX Bearish with a Setup Score of 35, net conviction 20, actionability 62. How the Setup Score works →
Total Setup Score
35
Directional Bias
Bearish
Net Conviction
20
Actionability
62 (in range)
Key signals behind this score
Fresh Breakdown — 10wk turn 2w
200wk Downtrend — falling+below (sma 4.94 vs px 4.17)
Short Attack — velZ +2.68 · age 16w×1.00 · 10.63%
Seasonal Headwind — september med -5.1% (mag 2/3) · posClose 8.33% (rel 2/3) · n12 ×1 = 11
About MacroGenics Inc
MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States. The company's product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resis… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: October 10, 2013
Headquarters: 9704 Medical Center Drive, Rockville, MD, United States, 20850
Founder-Led: Yes — Ezio Bonvini (Senior VP of Research & Chief Scientific Officer)
Key Metrics
Current Price
$4.17
Market Cap
$259M
Float
57.0M
Shares Outstanding
63.7M
P/E (Forward)
60.98
Price/Sales (TTM)
1.48
vs. Analyst Target
+73.9% to analyst PT
Profit Margin
-8.33%
Operating Margin (TTM)
-42.19%
Revenue (TTM)
$175M
Earnings Growth (YoY)
-70.40%
Dividend Rate
None
Analyst Target Price
$7.25 (7 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$97.8M
-$118M
$97.8M
-$119M
2021
$75.6M
-$191M
$73.0M
-$192M
2022
$152M
-$120M
$145M
-$110M
2023
$57.2M
-$9.1M
$49.0M
$2.0M
2024
$148M
-$67.0M
$136M
-$57.4M
2025
$150M
-$74.6M
$106M
-$59.6M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Sep 2025
$72.8M
$16.8M
Dec 2025
$41.2M
-$14.2M
Mar 2026
$20.8M
-$36.8M
Jun 2026
$32.8M
$19.5M
Ownership & Float
Insider Ownership
3.5%
Institutional Ownership
77.5%
Short Float
12.9%
% of All Funds Holding
1.39%
Number of Funds Holding
122
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$4.23
Near-term / short-term trend
Weekly
40-Week SMA
$3.03
Medium-term trend
Weekly
80-Week SMA
$2.34
Cyclical trend (business cycle)
Weekly
200-Week SMA
$4.94
Secular trend (multi-year)
Monthly
10-Month SMA
$2.96
Near-term monthly trend
Monthly
20-Month SMA
$2.36
Medium-term monthly trend
Monthly
40-Month SMA
$4.64
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$3.10
support
1.36x
2 months ago
$2.00
support
1.42x
4 months ago
Historical Earnings Reactions (52 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
-1.45%
-0.82%
36.54%
21.75%
-69.12%
1 Day
5.27%
1.02%
55.77%
230.92%
-77.44%
1 Week
3.27%
0.30%
51.92%
248.68%
-70.25%
2 Weeks
2.96%
0.44%
50.98%
239.61%
-68.98%
1 Month
2.65%
-4.35%
41.18%
164.08%
-65.99%
Next earnings: November 1, 2026 (66 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
-0.5%
30.8%
13
Feb
6.7%
61.5%
13
Mar
-3.8%
38.5%
13
Apr
1.6%
53.8%
13
May
3.5%
38.5%
13
Jun
4.1%
53.8%
13
Jul
-3.0%
23.1%
13
Aug
2.7%
50.0%
12
Sep
-7.0%
8.3%
12
Oct
1.4%
50.0%
12
Nov
11.3%
61.5%
13
Dec
-0.7%
46.2%
13
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.07%
49.2%
608
Tuesday
-0.03%
46.3%
667
Wednesday
0.62%
48.3%
662
Thursday
-0.08%
45.7%
650
Friday
-0.00%
51.2%
648
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 77.5%
Insider Transactions — Smart Summary
Total insider ownership: 3.5%
Founder-led management: Ezio Bonvini (Senior VP of Research & Chief Scientific Officer)
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for MacroGenics Inc
(MGNX) powered by Claude Opus — Anthropic's most capable AI model.
The analysis covers five layers:
technical analysis (near-term, medium-term, cyclical, and secular trend, momentum,
volume shelf support and resistance, breakout and breakdown signals),
qualitative analysis (business model, competitive moat, sector dynamics),
insider sentiment (buy and sell signals from executive and director transactions),
share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and
fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit,
stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward.
Whether you are building a long position, initiating a short, or looking for a reversal setup,
AI Consult identifies the highest-probability signal from the current trend.