Stock analysis, trade plans, and proprietary indicators by Trend Edge.
About MacroGenics Inc
MacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeutics for the treatment of cancer in the United States. The company's product pipeline includes lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4 for the treatment of mCRPC and docetaxel that is in phase 2 clinical trials, as well as for the treatment of platinum-resis… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: October 10, 2013
Headquarters: 9704 Medical Center Drive, Rockville, MD, United States, 20850
Founder-Led: Yes — Ezio Bonvini (Senior VP of Research & Chief Scientific Officer)
Key Metrics
Current Price
$4.38
Market Cap
$270M
Float
55.6M
Shares Outstanding
63.6M
P/E (Forward)
60.98
Price/Sales (TTM)
1.72
vs. Analyst Target
+54.1% to analyst PT
Profit Margin
-44.79%
Operating Margin (TTM)
-160.96%
Revenue (TTM)
$157M
Earnings Growth (YoY)
-70.40%
Dividend Rate
None
Analyst Target Price
$6.75 (7 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$97.8M
-$118M
$97.8M
-$119M
2021
$75.6M
-$191M
$73.0M
-$192M
2022
$152M
-$120M
$145M
-$110M
2023
$57.2M
-$9.1M
$49.0M
$2.0M
2024
$148M
-$67.0M
$136M
-$57.4M
2025
$150M
-$74.6M
$106M
-$65.7M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$22.2M
-$36.3M
Sep 2025
$72.8M
$16.8M
Dec 2025
$41.2M
-$14.2M
Mar 2026
$20.8M
-$36.8M
Ownership & Float
Insider Ownership
3.4%
Institutional Ownership
70.2%
Short Float
5.3%
% of All Funds Holding
1.24%
Number of Funds Holding
102
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$3.55
Near-term / short-term trend
Weekly
40-Week SMA
$2.22
Medium-term trend
Weekly
80-Week SMA
$2.17
Cyclical trend (business cycle)
Weekly
200-Week SMA
$4.94
Secular trend (multi-year)
Monthly
10-Month SMA
$2.24
Near-term monthly trend
Monthly
20-Month SMA
$2.28
Medium-term monthly trend
Monthly
40-Month SMA
$4.84
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$3.10
support
1.32x
0 months ago
$2.00
support
1.42x
1 months ago
$14.70
resistance
3.52x
23 months ago
$18.00
resistance
2.12x
25 months ago
Historical Earnings Reactions (51 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
-1.37%
-0.73%
37.25%
21.75%
-69.12%
1 Day
5.30%
0.65%
54.90%
230.92%
-77.44%
1 Week
3.33%
0.12%
50.98%
248.68%
-70.25%
2 Weeks
2.60%
0.20%
50.00%
239.61%
-68.98%
1 Month
2.45%
-4.54%
40.00%
164.08%
-65.99%
Next earnings: August 1, 2026 (64 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
-0.5%
30.8%
13
Feb
6.7%
61.5%
13
Mar
-3.8%
38.5%
13
Apr
1.6%
53.8%
13
May
0.8%
33.3%
12
Jun
3.5%
50.0%
12
Jul
-1.5%
25.0%
12
Aug
2.7%
50.0%
12
Sep
-7.0%
8.3%
12
Oct
1.4%
50.0%
12
Nov
11.3%
61.5%
13
Dec
-0.7%
46.2%
13
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.04%
49.1%
595
Tuesday
-0.01%
46.3%
655
Wednesday
0.64%
48.4%
649
Thursday
-0.08%
45.5%
637
Friday
0.01%
51.3%
637
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 70.2%
Insider Transactions — Smart Summary
Total insider ownership: 3.4%
Founder-led management: Ezio Bonvini (Senior VP of Research & Chief Scientific Officer)
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The analysis covers five layers:
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qualitative analysis (business model, competitive moat, sector dynamics),
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