MESO — Mesoblast Ltd

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Mesoblast Ltd

Mesoblast Limited, together with its subsidiaries, engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland. The company's proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. It offers Remestemcel-L, which is in Phase III clinical trials for the treatment of systemic inflammatory diseases, including steroid refractor… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$14.99
Market Cap$1.93B
Float819.9M
Shares Outstanding129.3M
P/E (Forward)454.55
Price/Sales (TTM)29.46
vs. Analyst Target+133.5% to analyst PT
Profit Margin-144.33%
Operating Margin (TTM)-55.16%
Revenue (TTM)$65.4M
Dividend RateNone
Analyst Target Price$35.00 (3 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $32.2M -$77.9M -$49.3M -$69.0M
2021 $7.5M -$98.8M -$78.3M -$84.7M
2022 $10.2M -$91.3M -$53.4M -$76.6M
2023 $7.5M -$81.9M -$47.4M -$58.5M
2024 $5.9M -$88.0M -$35.2M -$56.1M
2025 $17.2M -$102M $12.1M -$73.7M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2024 $1.6M -$24.0M
Dec 2024 $1.6M -$24.0M
Mar 2025 $7.0M -$27.1M
Jun 2025 $7.0M -$27.1M

Ownership & Float

Insider Ownership5.1%
Institutional Ownership2.9%
Short Float0.4%
% of All Funds Holding0.74%
Number of Funds Holding61

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$15.05Near-term / short-term trend
Weekly40-Week SMA$16.40Medium-term trend
Weekly80-Week SMA$14.97Cyclical trend (business cycle)
Weekly200-Week SMA$9.36Secular trend (multi-year)
Monthly10-Month SMA$16.10Near-term monthly trend
Monthly20-Month SMA$14.94Medium-term monthly trend
Monthly40-Month SMA$10.12Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$12.00 support 1.11x 9 months ago
$2.00 support 7.61x 25 months ago

Historical Earnings Reactions (42 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.83% 0.00% 47.62% 17.73% -13.39%
1 Day 0.10% -0.09% 45.24% 16.88% -13.29%
1 Week 0.21% -0.97% 47.62% 42.45% -19.51%
2 Weeks 2.47% -0.97% 47.62% 94.29% -41.87%
1 Month 5.25% -0.76% 42.86% 215.31% -47.33%

Next earnings: May 29, 2026 (11 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan1.0%50.0%16
Feb3.0%52.9%17
Mar11.1%41.2%17
Apr10.3%47.1%17
May-4.2%43.8%16
Jun-6.2%31.3%16
Jul9.2%68.8%16
Aug-4.6%18.8%16
Sep4.6%43.8%16
Oct-1.7%50.0%16
Nov3.5%62.5%16
Dec1.8%50.0%16

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.26% 40.6% 768
Tuesday -0.07% 40.0% 843
Wednesday 0.22% 44.0% 840
Thursday 0.08% 40.8% 826
Friday 0.11% 41.0% 824

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 2.9%

Insider Transactions — Smart Summary

Total insider ownership: 5.1%

Founder-led management: Silviu Itescu (Founder, Chief Executive Officer, Managing Director, Chairman of Scientific Advisory Board & Executive Director)

12-Month Insider Activity Summary

Total Filings2
Net Value+N/A
Net Shares Change16,216,924
% of Float2.0%
C-Suite Filings0
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
George Gregory +$37.5M 2 2 buy

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-04-13 George Gregory +$11.4M Transaction at $1.44, now +940.5%
2026-04-09 George Gregory +$26.1M Transaction at $3.15, now +376.4%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Mesoblast Ltd (MESO) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for MESO on Trend Edge →