MCRB — Seres Therapeutics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Seres Therapeutics Inc

Seres Therapeutics, Inc., a clinical-stage company, focuses on developing biotherapeutics for serious diseases. The company develops SER-155, an investigational oral live biotherapeutic to decolonize GI pathogens, enhance GI epithelial barrier integrity, and regulate immune response to prevent bacterial bloodstream infections, as well as other pathogen-associated negative clinical outcomes in patients undergoing allogeneic hematopoietic stem cell… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$7.63
Market Cap$77.5M
Float7.4M
Shares Outstanding9.7M
P/E (Forward)10.26
Price/Sales (TTM)67.60
vs. Analyst Target+188.3% to analyst PT
Operating Margin (TTM)-5839.94%
Revenue (TTM)$1.1M
Earnings Growth (YoY)-91.90%
Dividend RateNone
Analyst Target Price$22.00 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $33.2M -$89.1M -$57.4M -$77.3M
2021 $145M -$65.6M $145M -$56.7M
2022 $7.1M -$250M $6.1M -$171M
2023 $126M -$114M $126M -$181M
2024 N/A -$147M -$3.5M -$120M
2025 $789,000 $5.7M -$3.3M -$89.8M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$19.9M
Sep 2025 $351,000 $8.2M
Dec 2025 $438,000 -$15.3M
Mar 2026 $358,000 -$19.9M

Ownership & Float

Insider Ownership11.8%
Institutional Ownership24.4%
Short Float7.3%
% of All Funds Holding0.39%
Number of Funds Holding32

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$8.21Near-term / short-term trend
Weekly40-Week SMA$13.44Medium-term trend
Weekly80-Week SMA$13.49Cyclical trend (business cycle)
Weekly200-Week SMA$44.33Secular trend (multi-year)
Monthly10-Month SMA$13.47Near-term monthly trend
Monthly20-Month SMA$13.78Medium-term monthly trend
Monthly40-Month SMA$31.28Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Volume shelf data not available.

Historical Earnings Reactions (44 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.16% -0.03% 43.18% 6.28% -3.50%
1 Day 1.68% 0.17% 50.00% 39.48% -16.10%
1 Week 2.78% 1.86% 52.27% 32.01% -21.61%
2 Weeks 15.12% -0.16% 50.00% 377.14% -27.75%
1 Month 14.40% -0.36% 48.84% 488.10% -38.32%

Next earnings: July 24, 2026 (57 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-1.4%36.4%11
Feb-9.9%9.1%11
Mar0.5%63.6%11
Apr-5.9%45.5%11
May-5.6%60.0%10
Jun5.8%50.0%10
Jul-3.3%45.5%11
Aug60.0%63.6%11
Sep1.7%63.6%11
Oct-10.3%9.1%11
Nov9.2%63.6%11
Dec-10.0%9.1%11

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.81% 49.3% 513
Tuesday -0.06% 45.1% 566
Wednesday 0.22% 49.1% 562
Thursday -0.35% 46.2% 552
Friday -0.14% 47.5% 550

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 24.4%

Insider Transactions — Smart Summary

Total insider ownership: 11.8%

12-Month Insider Activity Summary

Total Filings16
Net Value-$48,219.39
Net Shares Change9,694
% of Float0.1%
C-Suite Filings12
Clusters Detected4

Key Insiders

NameTitleNet ValueFilingsActivity
Henn Matthew R Chief Scientific Officer and EVP -$23,079.74 3 N/A
Young Teresa L. EVP, Chief Commercial and Strategy Officer -$18,661.85 2 N/A
Shaff Eric D. -$4,144 2 N/A
DesRosier Thomas EVP and Chief Legal Officer -$1,255.53 2 N/A
Brady Kelly Chief Operating Officer, EVP -$444.27 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-19 – 2025-08-19 4 4 -$7,076.25 3 C-suite
2025-11-18 – 2025-11-18 4 4 -$44,841.6 3 C-suite
2026-02-18 – 2026-02-18 4 4 -$4,243.47 3 C-suite
2026-05-19 – 2026-05-19 4 4 -$3,569.22 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-05-19 Brady Kelly Chief Operating Officer, EVP -$444.27 Transaction at $7.53, now +1.3%
2025-11-18 Young Teresa L. EVP, Chief Commercial and Strategy Officer -$18,026.6 Transaction at $17.30, now -55.9%
2025-11-18 Henn Matthew R Chief Scientific Officer and EVP -$21,746.1 Transaction at $17.30, now -55.9%
2026-05-19 Shaff Eric D. -$1,950.27 Transaction at $7.53, now +1.3%
2026-05-19 Henn Matthew R Chief Scientific Officer and EVP -$579.81 Transaction at $7.53, now +1.3%
2026-05-19 DesRosier Thomas EVP and Chief Legal Officer -$594.87 Transaction at $7.53, now +1.3%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Seres Therapeutics Inc (MCRB) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for MCRB on Trend Edge →