Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge rates MAZE Bullish with a Setup Score of 63, net conviction 27, actionability 148. How the Setup Score works →
| Total Setup Score | 63 |
|---|---|
| Directional Bias | Bullish |
| Net Conviction | 27 |
| Actionability | 148 (in range) |
Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor that is in phase II ready c… Read full Trend Edge analysis →
| Current Price | $27.11 |
|---|---|
| Market Cap | $1.44B |
| Float | 36.8M |
| Shares Outstanding | 55.5M |
| P/E (Forward) | 8.53 |
| Price/Sales (TTM) | 71.88 |
| vs. Analyst Target | +126.9% to analyst PT |
| Operating Margin (TTM) | -728.06% |
| Revenue (TTM) | $20.0M |
| Dividend Rate | None |
| Analyst Target Price | $61.50 (13 analysts) |
| Year | Revenue | Net Income | Gross Profit | EBITDA |
|---|---|---|---|---|
| 2022 | N/A | -$115M | -$3.8M | -$111M |
| 2023 | N/A | -$100M | -$4.1M | -$96.3M |
| 2024 | $168M | $52.2M | $168M | $56.7M |
| 2025 | N/A | -$131M | -$2.4M | -$129M |
| Quarter | Revenue | Net Income |
|---|---|---|
| Sep 2025 | N/A | -$30.1M |
| Dec 2025 | N/A | -$34.6M |
| Mar 2026 | $20.0M | -$24.2M |
| Jun 2026 | N/A | -$44.7M |
| Insider Ownership | 1.5% |
|---|---|
| Institutional Ownership | 106.9% |
| Short Float | 16.1% |
| % of All Funds Holding | 1.85% |
| Number of Funds Holding | 163 |
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
| Timeframe | SMA | Value | Trend Context |
|---|---|---|---|
| Weekly | 10-Week SMA | $26.56 | Near-term / short-term trend |
| Weekly | 40-Week SMA | $31.90 | Medium-term trend |
| Weekly | 80-Week SMA | $26.43 | Cyclical trend (business cycle) |
| Weekly | 200-Week SMA | $0.00 | Secular trend (multi-year) |
| Monthly | 10-Month SMA | $30.97 | Near-term monthly trend |
| Monthly | 20-Month SMA | $25.97 | Medium-term monthly trend |
| Monthly | 40-Month SMA | $0.00 | Secular monthly trend |
Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
| Price Level | Type | Volume Ratio | Age |
|---|---|---|---|
| $25.10 | support | 1.21x | 3 months ago |
| $44.00 | resistance | 2.61x | 6 months ago |
| Timeframe | Avg Return | Median | Win Rate | Best | Worst |
|---|---|---|---|---|---|
| Gap | -0.45% | 0.62% | 57.14% | 1.89% | -2.82% |
| 1 Day | -1.02% | -0.06% | 42.86% | 4.58% | -10.08% |
| 1 Week | -2.08% | -1.89% | 42.86% | 12.25% | -31.24% |
| 2 Weeks | 0.32% | 2.40% | 71.43% | 22.38% | -26.43% |
| 1 Month | 14.44% | -1.45% | 42.86% | 69.21% | -18.22% |
Next earnings: November 5, 2026 (24 days away)
Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).
Institutional holder breakdown coming soon.
Total institutional ownership: 106.9%
Total insider ownership: 1.5%
| Total Filings | 43 |
|---|---|
| Net Value | -$18.1M |
| Net Shares Change | -190,072 |
| % of Float | -0.5% |
| C-Suite Filings | 42 |
| Clusters Detected | 9 |
| Name | Title | Net Value | Filings | Activity |
|---|---|---|---|---|
| Coloma Jason V | Chief Executive Officer | -$4.4M | 5 | 1 sell |
| Sohn Catherine A. | -$842,570.681 | 1 | 1 sell | |
| Bernstein Harold | President, R&D & CMO | -$527,433.843 | 2 | 1 sell |
| Dandekar Atul | CSBO | -$168,810.788 | 1 | 1 sell |
| Courtney Phillips | GC and Corp. Secretary | -$104,765.539 | 1 | 1 sell |
| Period | Filings | Insiders | Net Value | Seniority |
|---|---|---|---|---|
| 2025-12-31 – 2026-01-09 | 7 | 4 | -$5.9M | 6 C-suite |
| 2026-01-26 – 2026-02-04 | 4 | 3 | -$1.1M | 4 C-suite |
| 2026-03-03 – 2026-03-12 | 3 | 3 | -$1.6M | 3 C-suite |
| 2026-03-20 – 2026-04-02 | 4 | 3 | -$1.1M | 4 C-suite |
| 2026-06-02 – 2026-06-03 | 3 | 3 | -$519,795.06 | 3 C-suite |
| 2026-06-24 – 2026-07-02 | 4 | 3 | -$2.2M | 4 C-suite |
| 2026-07-31 – 2026-08-14 | 3 | 3 | -$1.3M | 3 C-suite |
| 2026-08-31 – 2026-09-08 | 8 | 4 | -$2.7M | 8 C-suite |
| 2026-10-01 – 2026-10-02 | 3 | 3 | -$1.3M | 3 C-suite |
| Date | Insider | Title | Net Value | Price After |
|---|---|---|---|---|
| 2026-09-04 | Dandekar Atul | CSBO | -$168,810.788 | Transaction at $26.24, now +3.3% |
| 2026-09-04 | Courtney Phillips | GC and Corp. Secretary | -$104,765.539 | Transaction at $26.24, now +3.3% |
| 2026-09-04 | Bernstein Harold | President, R&D & CMO | -$270,110.945 | Transaction at $26.24, now +3.3% |
| 2026-09-04 | Coloma Jason V | Chief Executive Officer | -$593,955.47 | Transaction at $26.24, now +3.3% |
| 2026-10-02 | Coloma Jason V | Chief Executive Officer | -$932,258.421 | Transaction at $27.02, now +0.3% |
| 2026-09-03 | Bernstein Harold | President, R&D & CMO | -$257,322.899 | Transaction at $15.51, now +74.8% |
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Maze Therapeutics, Inc. Common Stock (MAZE) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.
Get the full AI Consult analysis for MAZE on Trend Edge →