Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Trend Edge rates KYMR Bullish with a Setup Score of 0, net conviction 49, actionability 0. How the Setup Score works →
| Total Setup Score | 0 |
|---|---|
| Directional Bias | Bullish |
| Net Conviction | 49 |
| Actionability | 0 (extended) |
Kymera Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing KT-621, an oral STAT6 degrader in Phase 2b clinical trials for moderate to severe atopic dermatitis, asthma, COPD, EoE, CRSwNP, CSU, PN, BP, and others; KT-579, an oral IRF5… Read full Trend Edge analysis →
| Current Price | $110.40 |
|---|---|
| Market Cap | $9.79B |
| Float | 65.2M |
| Shares Outstanding | 82.3M |
| Price/Sales (TTM) | 190.16 |
| vs. Analyst Target | +12.1% to analyst PT |
| Operating Margin (TTM) | -244.88% |
| Revenue (TTM) | $51.5M |
| Dividend Rate | None |
| Analyst Target Price | $123.76 (20 analysts) |
| Year | Revenue | Net Income | Gross Profit | EBITDA |
|---|---|---|---|---|
| 2020 | $34.0M | -$45.6M | $34.0M | -$43.7M |
| 2021 | $72.8M | -$100M | $72.8M | -$97.6M |
| 2022 | $46.8M | -$155M | $46.8M | -$152M |
| 2023 | $78.6M | -$147M | $78.6M | -$143M |
| 2024 | $47.1M | -$224M | $47.1M | -$216M |
| 2025 | $39.2M | -$311M | $39.2M | -$303M |
| Quarter | Revenue | Net Income |
|---|---|---|
| Jun 2025 | $11.5M | -$76.6M |
| Sep 2025 | $2.8M | -$82.2M |
| Dec 2025 | $2.9M | -$87.0M |
| Mar 2026 | $34.4M | -$69.2M |
| Insider Ownership | 2.1% |
|---|---|
| Institutional Ownership | 115.6% |
| Short Float | 15.3% |
| % of All Funds Holding | 2.88% |
| Number of Funds Holding | 237 |
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
| Timeframe | SMA | Value | Trend Context |
|---|---|---|---|
| Weekly | 10-Week SMA | $94.47 | Near-term / short-term trend |
| Weekly | 40-Week SMA | $80.82 | Medium-term trend |
| Weekly | 80-Week SMA | $60.20 | Cyclical trend (business cycle) |
| Weekly | 200-Week SMA | $43.08 | Secular trend (multi-year) |
| Monthly | 10-Month SMA | $84.24 | Near-term monthly trend |
| Monthly | 20-Month SMA | $61.50 | Medium-term monthly trend |
| Monthly | 40-Month SMA | $46.82 | Secular monthly trend |
Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
| Price Level | Type | Volume Ratio | Age |
|---|---|---|---|
| $81.00 | support | 1.54x | 0 months ago |
| $67.00 | support | 1.71x | 6 months ago |
| $42.00 | support | 1.30x | 9 months ago |
| $27.40 | support | 1.61x | 14 months ago |
| Timeframe | Avg Return | Median | Win Rate | Best | Worst |
|---|---|---|---|---|---|
| Gap | 0.84% | 0.19% | 50.00% | 5.98% | -1.76% |
| 1 Day | 2.15% | 1.41% | 66.67% | 18.13% | -14.49% |
| 1 Week | 1.43% | 4.10% | 58.33% | 20.20% | -33.28% |
| 2 Weeks | 1.85% | 0.26% | 50.00% | 60.84% | -37.62% |
| 1 Month | 9.63% | 7.83% | 52.17% | 82.86% | -35.89% |
Next earnings: August 10, 2026 (27 days away)
Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).
| Day | Avg Return | Win Rate | Samples |
|---|---|---|---|
| Monday | 0.04% | 47.6% | 275 |
| Tuesday | 0.17% | 51.6% | 306 |
| Wednesday | 0.32% | 49.3% | 304 |
| Thursday | 0.12% | 48.3% | 296 |
| Friday | 0.31% | 50.5% | 295 |
Institutional holder breakdown coming soon.
Total institutional ownership: 115.6%
Total insider ownership: 2.1%
Founder-led management: Nello Mainolfi (Co-Founder, President, Chief Executive Officer & Director), Bruce L. Booth (Co-Founder & Independent Chairman)
| Total Filings | 44 |
|---|---|
| Net Value | -$68.9M |
| Net Shares Change | -1,254,981 |
| % of Float | -1.9% |
| C-Suite Filings | 27 |
| Clusters Detected | 5 |
| Name | Title | Net Value | Filings | Activity |
|---|---|---|---|---|
| BVF PARTNERS L P/IL | -$174M | 1 | 2 sell | |
| BAKER BROS. ADVISORS LP | +$172M | 1 | 1 buy | |
| Booth Bruce | -$100M | 2 | 1 sell | |
| Jacobs Bruce N. | Chief Financial Officer | -$9.6M | 2 | 1 sell |
| Chadwick Jeremy G | Chief Operating Officer | -$1.9M | 2 | 1 sell |
| Gollob Jared | Chief Medical Officer | -$916,668.532 | 1 | 1 sell |
| Goodman Noah | Chief Business Officer | -$387,328.81 | 1 | N/A |
| Period | Filings | Insiders | Net Value | Seniority |
|---|---|---|---|---|
| 2025-12-08 – 2025-12-17 | 6 | 6 | +$136M | 2 C-suite |
| 2026-02-20 – 2026-03-04 | 6 | 6 | -$12.6M | 4 C-suite |
| 2026-04-01 – 2026-04-10 | 3 | 3 | -$2.9M | 2 C-suite |
| 2026-04-16 – 2026-04-29 | 6 | 4 | -$4.1M | 4 C-suite |
| 2026-06-22 – 2026-07-02 | 9 | 5 | -$328M | 5 C-suite |
| Date | Insider | Title | Net Value | Price After |
|---|---|---|---|---|
| 2026-06-26 | BVF PARTNERS L P/IL | -$174M | Transaction at $106.50, now +3.7% | |
| 2025-12-11 | BAKER BROS. ADVISORS LP | +$172M | Transaction at $86.00, now +28.4% | |
| 2026-03-04 | Gollob Jared | Chief Medical Officer | -$916,668.532 | Transaction at $87.24, now +26.6% |
| 2026-03-04 | Chadwick Jeremy G | Chief Operating Officer | -$515,594 | Transaction at $86.54, now +27.6% |
| 2026-03-04 | Jacobs Bruce N. | Chief Financial Officer | -$1.1M | Transaction at $87.50, now +26.2% |
| 2026-06-25 | Booth Bruce | -$78.8M | Transaction at $115.13, now -4.1% |
Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Kymera Therapeutics Inc (KYMR) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).
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Get the full AI Consult analysis for KYMR on Trend Edge →