Stock analysis, trade plans, and proprietary indicators by Trend Edge.
About Krystal Biotech Inc
Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic … Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: September 20, 2017
Headquarters: 2100 Wharton Street, Pittsburgh, PA, United States, 15203
Founder-Led: Yes — Krish Krishnan (Founder, Chairman, President & CEO), Suma Krishnan (Founder, President of R&D and Director)
Key Metrics
Current Price
$306.63
Market Cap
$8.94B
Float
23.4M
Shares Outstanding
29.5M
P/E (Forward)
44.64
P/E (TTM)
40.65
Price/Sales (TTM)
21.42
vs. Analyst Target
+5.3% to analyst PT
Profit Margin
53.93%
Operating Margin (TTM)
46.14%
Revenue (TTM)
$417M
Earnings Growth (YoY)
52.50%
Dividend Rate
None
Analyst Target Price
$322.78 (11 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
N/A
-$32.2M
-$1.9M
-$30.3M
2021
N/A
-$69.6M
-$2.8M
-$66.2M
2022
N/A
-$140M
-$4.1M
-$117M
2023
$50.7M
$10.9M
$47.6M
-$91.3M
2024
$291M
$89.2M
$270M
$110M
2025
$389M
$205M
$360M
$168M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$96.0M
$38.3M
Sep 2025
$97.8M
$79.4M
Dec 2025
$107M
$51.4M
Mar 2026
$116M
$55.9M
Ownership & Float
Insider Ownership
11.1%
Institutional Ownership
99.2%
Short Float
13.2%
% of All Funds Holding
4.11%
Number of Funds Holding
338
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$279.62
Near-term / short-term trend
Weekly
40-Week SMA
$237.68
Medium-term trend
Weekly
80-Week SMA
$197.86
Cyclical trend (business cycle)
Weekly
200-Week SMA
$153.05
Secular trend (multi-year)
Monthly
10-Month SMA
$236.84
Near-term monthly trend
Monthly
20-Month SMA
$200.07
Medium-term monthly trend
Monthly
40-Month SMA
$168.21
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$148.00
support
1.12x
7 months ago
Historical Earnings Reactions (36 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
0.37%
0.49%
61.11%
6.05%
-8.35%
1 Day
0.54%
-0.43%
47.22%
8.60%
-7.54%
1 Week
0.57%
0.45%
52.78%
20.21%
-35.14%
2 Weeks
3.11%
2.37%
57.14%
35.92%
-30.17%
1 Month
8.34%
2.98%
62.86%
51.88%
-20.17%
Next earnings: May 11, 2026
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
1.2%
55.6%
9
Feb
8.2%
66.7%
9
Mar
3.8%
55.6%
9
Apr
-1.7%
44.4%
9
May
1.3%
50.0%
8
Jun
11.6%
75.0%
8
Jul
7.7%
75.0%
8
Aug
-1.1%
12.5%
8
Sep
-3.8%
25.0%
8
Oct
5.3%
55.6%
9
Nov
19.0%
88.9%
9
Dec
-1.2%
55.6%
9
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.38%
48.8%
408
Tuesday
0.35%
53.8%
450
Wednesday
0.16%
50.8%
445
Thursday
0.03%
50.2%
438
Friday
0.31%
53.1%
439
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 99.2%
Insider Transactions — Smart Summary
Total insider ownership: 11.1%
Founder-led management: Krish Krishnan (Founder, Chairman, President & CEO), Suma Krishnan (Founder, President of R&D and Director)
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