Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic … Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: September 20, 2017
Headquarters: 2100 Wharton Street, Pittsburgh, PA, United States, 15203
Founder-Led: Yes — Krish Krishnan (Founder, Chairman, President & CEO), Suma Krishnan (Founder, President of R&D and Director)
Key Metrics
Current Price
$356.97
Market Cap
$10.03B
Float
23.6M
Shares Outstanding
29.6M
P/E (Forward)
41.32
P/E (TTM)
42.43
Price/Sales (TTM)
22.78
vs. Analyst Target
+7.9% to analyst PT
Profit Margin
54.82%
Operating Margin (TTM)
49.00%
Revenue (TTM)
$440M
Earnings Growth (YoY)
38.80%
Dividend Rate
None
Analyst Target Price
$385.00 (11 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
N/A
-$32.2M
-$1.9M
-$30.3M
2021
N/A
-$69.6M
-$2.8M
-$66.2M
2022
N/A
-$140M
-$4.1M
-$117M
2023
$50.7M
$10.9M
$47.6M
-$91.3M
2024
$291M
$89.2M
$270M
$110M
2025
$389M
$205M
$360M
$196M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Sep 2025
$97.8M
$79.4M
Dec 2025
$107M
$51.4M
Mar 2026
$116M
$55.9M
Jun 2026
$119M
$54.8M
Ownership & Float
Insider Ownership
10.8%
Institutional Ownership
102.5%
Short Float
13.6%
% of All Funds Holding
4.79%
Number of Funds Holding
421
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$350.66
Near-term / short-term trend
Weekly
40-Week SMA
$291.38
Medium-term trend
Weekly
80-Week SMA
$227.02
Cyclical trend (business cycle)
Weekly
200-Week SMA
$170.76
Secular trend (multi-year)
Monthly
10-Month SMA
$291.88
Near-term monthly trend
Monthly
20-Month SMA
$227.35
Medium-term monthly trend
Monthly
40-Month SMA
$188.87
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$310.00
support
1.27x
1 months ago
$148.00
support
1.12x
10 months ago
$139.00
support
1.02x
12 months ago
Historical Earnings Reactions (37 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
0.36%
0.63%
62.16%
6.05%
-8.35%
1 Day
0.52%
-0.33%
48.65%
8.60%
-8.37%
1 Week
0.70%
0.85%
54.05%
20.21%
-35.14%
2 Weeks
3.01%
1.59%
56.76%
35.92%
-30.17%
1 Month
8.30%
2.98%
62.86%
51.88%
-20.17%
Next earnings: October 22, 2026 (56 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
1.2%
55.6%
9
Feb
8.2%
66.7%
9
Mar
3.8%
55.6%
9
Apr
-1.7%
44.4%
9
May
3.1%
55.6%
9
Jun
12.5%
77.8%
9
Jul
5.9%
66.7%
9
Aug
-1.1%
12.5%
8
Sep
-3.8%
25.0%
8
Oct
5.3%
55.6%
9
Nov
19.0%
88.9%
9
Dec
-1.2%
55.6%
9
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.35%
48.7%
421
Tuesday
0.33%
53.0%
462
Wednesday
0.21%
51.5%
458
Thursday
0.04%
50.3%
451
Friday
0.31%
53.1%
450
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 102.5%
Insider Transactions — Smart Summary
Total insider ownership: 10.8%
Founder-led management: Krish Krishnan (Founder, Chairman, President & CEO), Suma Krishnan (Founder, President of R&D and Director)
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