GPCR — Structure Therapeutics Inc. American Depositary Shares

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates GPCR Bullish with a Setup Score of 42, net conviction 27, actionability 64. How the Setup Score works →

Total Setup Score42
Directional BiasBullish
Net Conviction27
Actionability64 (in range)

Key signals behind this score

About Structure Therapeutics Inc. American Depositary Shares

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, which is in two phase 2 clinical trials for the treatment of obesity, overweight, and related conditions. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$53.36
Market Cap$3.92B
Float54.9M
Shares Outstanding71.1M
vs. Analyst Target+96.0% to analyst PT
Dividend RateNone
Analyst Target Price$104.59 (14 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 N/A -$15,876 -$20,034 -$15,906
2021 N/A -$40.0M -$266,353 -$37.6M
2022 N/A -$51.3M -$623,258 -$52.3M
2023 N/A -$89.6M -$949,174 -$75.7M
2024 N/A -$123M -$2.6M -$121M
2025 N/A -$141M -$3.9M -$137M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$61.7M
Sep 2025 N/A -$65.7M
Dec 2025 N/A $33.0M
Mar 2026 N/A -$76.2M

Ownership & Float

Insider Ownership2.7%
Institutional Ownership96.0%
Short Float10.7%
% of All Funds Holding2.18%
Number of Funds Holding179

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$43.79Near-term / short-term trend
Weekly40-Week SMA$51.52Medium-term trend
Weekly80-Week SMA$36.97Cyclical trend (business cycle)
Weekly200-Week SMA$0.00Secular trend (multi-year)
Monthly10-Month SMA$52.61Near-term monthly trend
Monthly20-Month SMA$37.94Medium-term monthly trend
Monthly40-Month SMA$39.44Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$35.30 support 2.14x 6 months ago
$19.20 support 1.48x 9 months ago
$17.10 support 1.57x 14 months ago

Historical Earnings Reactions (14 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.43% 0.16% 50.00% 8.46% -4.48%
1 Day -1.37% -1.98% 28.57% 7.65% -9.83%
1 Week -1.24% -3.59% 28.57% 13.61% -17.24%
2 Weeks 3.85% 1.81% 64.29% 28.00% -16.99%
1 Month 8.36% 9.20% 61.54% 105.98% -36.87%

Next earnings: August 5, 2026 (23 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.68% 50.6% 162
Tuesday -0.04% 45.2% 177
Wednesday -0.25% 46.3% 175
Thursday 0.29% 48.8% 170
Friday 0.62% 50.9% 171

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 96.0%

Insider Transactions — Smart Summary

Total insider ownership: 2.7%

Founder-led management: Raymond C. Stevens (CEO & Director), Jun S. Yoon (Co-Founder, CFO & Secretary)

Full insider transaction history and smart buy/sell sentiment summary available on Trend Edge.

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Structure Therapeutics Inc. American Depositary Shares (GPCR) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for GPCR on Trend Edge →