ENTA — Enanta Pharmaceuticals Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates ENTA Bearish with a Setup Score of 0, net conviction 20, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBearish
Net Conviction20
Actionability0 (extended)

Key signals behind this score

About Enanta Pharmaceuticals Inc

Enanta Pharmaceuticals, Inc., a biotechnology company, discovers and develops small molecule drugs for virology and immunology indications. The company's product pipeline comprises EDP-514, which is in phase 1b clinical development for the treatment of chronic infection with hepatitis B virus or HBV; zelicapavir and EDP-323, which is in phase II clinical development for the treatment of respiratory syncytial virus; EDP-235, which is in phase II c… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$14.10
Market Cap$382M
Float22.5M
Shares Outstanding29.1M
P/E (Forward)44.05
Price/Sales (TTM)5.86
vs. Analyst Target+50.1% to analyst PT
Profit Margin-96.89%
Operating Margin (TTM)-120.04%
Revenue (TTM)$65.3M
Earnings Growth (YoY)-66.20%
Dividend RateNone
Analyst Target Price$21.17 (6 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $122M -$36.2M $122M -$38.0M
2021 $97.1M -$79.0M $97.1M -$106M
2022 $86.2M -$122M $86.2M -$119M
2023 $79.2M -$134M $79.2M -$123M
2024 $67.6M -$116M $67.6M -$105M
2025 $65.3M -$81.9M $60.7M -$70.8M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $15.1M -$18.7M
Dec 2025 $18.6M -$11.9M
Mar 2026 $17.2M -$13.1M
Jun 2026 $14.4M -$19.5M

Ownership & Float

Insider Ownership4.7%
Institutional Ownership94.3%
Short Float11.5%
% of All Funds Holding1.40%
Number of Funds Holding123

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$13.64Near-term / short-term trend
Weekly40-Week SMA$13.62Medium-term trend
Weekly80-Week SMA$10.70Cyclical trend (business cycle)
Weekly200-Week SMA$16.33Secular trend (multi-year)
Monthly10-Month SMA$13.81Near-term monthly trend
Monthly20-Month SMA$10.75Medium-term monthly trend
Monthly40-Month SMA$11.98Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$8.70 support 2.94x 10 months ago
$5.10 support 1.77x 17 months ago

Historical Earnings Reactions (54 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.63% -0.10% 48.15% 23.88% -30.09%
1 Day -0.36% -0.25% 48.15% 15.06% -25.66%
1 Week 1.80% 0.13% 50.00% 69.39% -28.23%
2 Weeks 2.12% 0.23% 50.94% 65.10% -25.88%
1 Month 1.73% 0.99% 54.72% 37.08% -35.07%

Next earnings: October 29, 2026 (64 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.4%46.2%13
Feb7.3%61.5%13
Mar-2.6%53.8%13
Apr-0.4%50.0%14
May-5.2%35.7%14
Jun5.2%57.1%14
Jul-1.6%50.0%14
Aug1.8%53.8%13
Sep-0.8%30.8%13
Oct-2.0%38.5%13
Nov7.7%69.2%13
Dec-0.2%69.2%13

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.21% 50.5% 634
Tuesday 0.09% 51.3% 696
Wednesday 0.11% 51.8% 691
Thursday -0.14% 46.9% 678
Friday 0.04% 49.6% 676

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 94.3%

Insider Transactions — Smart Summary

Total insider ownership: 4.7%

12-Month Insider Activity Summary

Total Filings9
Net Value-$185,849.4
Net Shares Change-13,073
% of Float-0.1%
C-Suite Filings9
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
Luly Jay R. President and CEO -$67,492.89 1 N/A
Or Yat Sun Chief Scientific Officer -$34,009.7 1 N/A
Kieffer Tara Lynn Chief Product Strategy Officer -$29,968.38 1 N/A
Luu Brendan Chief Business Officer -$19,836.62 1 N/A
Trout Harry R. III Vice President, Finance (Principal Financial Officer) -$14,500.06 2 N/A
Rottinghaus Scott T. Chief Medical Officer -$11,355.54 1 N/A
Capps Kathleen S. Executive Director of Accounting, Controller (Principal Accounting Officer) -$8,686.21 2 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-12-03 – 2025-12-05 9 7 -$185,849.4 9 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-12-05 Kieffer Tara Lynn Chief Product Strategy Officer -$29,968.38 Transaction at $14.23, now -0.9%
2025-12-05 Luu Brendan Chief Business Officer -$19,836.62 Transaction at $14.23, now -0.9%
2025-12-05 Trout Harry R. III Vice President, Finance (Principal Financial Officer) -$7,712.66 Transaction at $14.23, now -0.9%
2025-12-05 Rottinghaus Scott T. Chief Medical Officer -$11,355.54 Transaction at $14.23, now -0.9%
2025-12-05 Or Yat Sun Chief Scientific Officer -$34,009.7 Transaction at $14.23, now -0.9%
2025-12-05 Luly Jay R. President and CEO -$67,492.89 Transaction at $14.23, now -0.9%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Enanta Pharmaceuticals Inc (ENTA) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ENTA on Trend Edge →