DTIL — Precision BioSciences Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Precision BioSciences Inc

Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, … Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$7.59
Market Cap$185M
Float20.1M
Shares Outstanding25.8M
P/E (Forward)11.78
Price/Sales (TTM)4.11
vs. Analyst Target+321.6% to analyst PT
Profit Margin-96.73%
Operating Margin (TTM)-83.73%
Revenue (TTM)$45.1M
Dividend RateNone
Analyst Target Price$32.00 (4 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $24.3M -$109M $24.3M -$99.2M
2021 $116M -$30.6M $116M -$20.3M
2022 $25.1M -$112M $25.1M -$62.8M
2023 $48.7M -$61.3M $48.7M -$32.0M
2024 $68.7M $7.2M $68.7M $13.5M
2025 $34.3M -$46.6M $31.5M -$49.4M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $18,000 -$23.5M
Sep 2025 $13,000 -$21.8M
Dec 2025 $34.2M $19.2M
Mar 2026 $10.8M -$18.4M

Ownership & Float

Insider Ownership6.0%
Institutional Ownership65.6%
Short Float7.0%
% of All Funds Holding0.84%
Number of Funds Holding69

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$7.05Near-term / short-term trend
Weekly40-Week SMA$5.54Medium-term trend
Weekly80-Week SMA$5.31Cyclical trend (business cycle)
Weekly200-Week SMA$14.59Secular trend (multi-year)
Monthly10-Month SMA$5.66Near-term monthly trend
Monthly20-Month SMA$5.54Medium-term monthly trend
Monthly40-Month SMA$10.21Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$5.50 support 1.08x 0 months ago
$4.10 support 1.67x 1 months ago
$14.00 resistance 1.50x 24 months ago

Historical Earnings Reactions (30 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 1.82% 0.10% 53.33% 51.11% -8.39%
1 Day -0.72% -0.28% 46.67% 26.67% -14.27%
1 Week -2.23% -1.75% 43.33% 38.93% -28.80%
2 Weeks -0.97% -3.33% 40.00% 102.22% -29.92%
1 Month -5.81% -4.06% 34.48% 30.41% -44.21%

Next earnings: May 21, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-0.6%42.9%7
Feb8.7%42.9%7
Mar-15.1%14.3%7
Apr-2.8%50.0%8
May0.1%57.1%7
Jun-5.0%28.6%7
Jul-5.0%28.6%7
Aug-1.5%57.1%7
Sep-7.3%28.6%7
Oct0.5%42.9%7
Nov33.1%42.9%7
Dec-22.1%14.3%7

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.22% 46.3% 337
Tuesday 0.45% 49.6% 373
Wednesday -0.07% 46.2% 368
Thursday -0.42% 43.9% 360
Friday -0.22% 41.8% 361

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 65.6%

Insider Transactions — Smart Summary

Total insider ownership: 6.0%

Founder-led management: Jeff Smith (Chief Research Officer)

12-Month Insider Activity Summary

Total Filings19
Net Value-$529,330.31
Net Shares Change247,928
% of Float1.2%
C-Suite Filings12
Clusters Detected5

Key Insiders

NameTitleNet ValueFilingsActivity
Kelly John Alexander Chief Financial Officer -$31,292.16 1 N/A
Frankel Stanley +$26,109 2 2 buy
Buehler Kevin +$21,116.16 1 1 buy
Brown Melinda +$20,673.05 3 3 buy
Scimeca Dario General Counsel and Secretary -$18,912 1 N/A
SMITH J. JEFFERSON Chief Research Officer -$18,912 1 N/A
Germano Geno J +$14,160 1 1 buy

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-06-27 – 2025-07-08 3 3 -$35,083.38 1 C-suite
2025-11-04 – 2025-11-04 3 3 -$34,896.73 3 C-suite
2025-12-17 – 2025-12-17 3 3 +$33,713.57
2026-01-22 – 2026-01-22 4 4 -$283,207.84 4 C-suite
2026-02-19 – 2026-02-19 4 4 -$148,062.72 4 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-12-17 Germano Geno J +$14,160 Transaction at $4.72, now +60.8%
2025-12-17 Frankel Stanley +$12,690 Transaction at $4.70, now +61.5%
2025-12-17 Brown Melinda +$6,863.57 Transaction at $4.97, now +52.7%
2025-09-30 Frankel Stanley +$13,419 Transaction at $4.97, now +52.7%
2025-06-27 Buehler Kevin +$21,116.16 Transaction at $4.16, now +82.5%
2025-09-24 Brown Melinda +$6,846 Transaction at $4.89, now +55.2%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Precision BioSciences Inc (DTIL) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for DTIL on Trend Edge →