Precision BioSciences, Inc., a clinical stage gene editing company, develops in vivo gene editing therapies for gene edits, including gene insertion, excision, and elimination in the United States. The company offers ARCUS, a genome editing platform for DNA genome insertion, removal, and repair. It also provides PBGENE-HBV for the treatment of chronic hepatitis B virus (HBV) to eliminate covalently closed circular DNA with direct cuts and edits, … Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: March 28, 2019
Headquarters: 302 East Pettigrew St., Durham, NC, United States, 27701
Founder-Led: Yes — Jeff Smith (Chief Research Officer)
Key Metrics
Current Price
$6.72
Market Cap
$177M
Float
25.5M
Shares Outstanding
27.6M
P/E (Forward)
11.78
Price/Sales (TTM)
3.94
vs. Analyst Target
+337.5% to analyst PT
Profit Margin
-117.04%
Operating Margin (TTM)
-80.78%
Revenue (TTM)
$45.1M
Dividend Rate
None
Analyst Target Price
$29.40 (5 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$24.3M
-$109M
$24.3M
-$99.2M
2021
$116M
-$30.6M
$116M
-$20.3M
2022
$25.1M
-$112M
$25.1M
-$62.8M
2023
$48.7M
-$61.3M
$48.7M
-$32.0M
2024
$68.7M
$7.2M
$68.7M
$13.5M
2025
$34.3M
-$45.7M
$34.3M
-$42.4M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Sep 2025
$13,000
-$21.8M
Dec 2025
$34.2M
$20.1M
Mar 2026
$10.8M
-$18.4M
Jun 2026
N/A
-$32.7M
Ownership & Float
Insider Ownership
8.0%
Institutional Ownership
68.7%
Short Float
9.9%
% of All Funds Holding
1.09%
Number of Funds Holding
96
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$7.21
Near-term / short-term trend
Weekly
40-Week SMA
$6.41
Medium-term trend
Weekly
80-Week SMA
$5.75
Cyclical trend (business cycle)
Weekly
200-Week SMA
$11.06
Secular trend (multi-year)
Monthly
10-Month SMA
$6.33
Near-term monthly trend
Monthly
20-Month SMA
$5.78
Medium-term monthly trend
Monthly
40-Month SMA
$8.09
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$5.70
support
1.06x
5 months ago
$4.10
support
1.67x
6 months ago
$8.60
resistance
1.16x
22 months ago
Historical Earnings Reactions (31 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
1.78%
0.13%
54.84%
51.11%
-8.39%
1 Day
-0.67%
-0.23%
48.39%
26.67%
-14.27%
1 Week
-2.16%
-1.56%
45.16%
38.93%
-28.80%
2 Weeks
-0.32%
-3.04%
41.94%
102.22%
-29.92%
1 Month
-5.92%
-5.00%
33.33%
30.41%
-44.21%
Next earnings: November 2, 2026 (22 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
-0.6%
42.9%
7
Feb
8.7%
42.9%
7
Mar
-15.1%
14.3%
7
Apr
-2.8%
50.0%
8
May
-0.2%
50.0%
8
Jun
-2.8%
37.5%
8
Jul
-5.8%
25.0%
8
Aug
-0.2%
62.5%
8
Sep
-8.6%
25.0%
8
Oct
0.5%
42.9%
7
Nov
33.1%
42.9%
7
Dec
-22.1%
14.3%
7
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
-0.21%
46.2%
355
Tuesday
0.49%
49.6%
391
Wednesday
-0.13%
46.3%
387
Thursday
-0.41%
44.1%
379
Friday
-0.23%
41.8%
378
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 68.7%
Insider Transactions — Smart Summary
Total insider ownership: 8.0%
Founder-led management: Jeff Smith (Chief Research Officer)
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