CYTK — Cytokinetics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Cytokinetics Inc

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$75.85
Market Cap$10.68B
Float123.9M
Shares Outstanding135.8M
P/E (Forward)117.65
Price/Sales (TTM)100.90
vs. Analyst Target+38.4% to analyst PT
Operating Margin (TTM)-948.69%
Revenue (TTM)$106M
Dividend RateNone
Analyst Target Price$105.00 (21 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $55.8M -$127M -$41.1M -$86.8M
2021 $70.4M -$215M -$89.5M -$176M
2022 $94.6M -$389M -$146M -$329M
2023 $7.5M -$526M -$323M -$457M
2024 $18.5M -$590M -$321M -$493M
2025 $88.0M -$785M $77.9M -$775M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $66.8M -$134M
Sep 2025 $1.9M -$306M
Dec 2025 $17.8M -$183M
Mar 2026 $19.4M -$206M

Ownership & Float

Insider Ownership0.7%
Institutional Ownership116.3%
Short Float12.8%
% of All Funds Holding4.90%
Number of Funds Holding378

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$66.41Near-term / short-term trend
Weekly40-Week SMA$60.60Medium-term trend
Weekly80-Week SMA$51.24Cyclical trend (business cycle)
Weekly200-Week SMA$49.55Secular trend (multi-year)
Monthly10-Month SMA$61.67Near-term monthly trend
Monthly20-Month SMA$52.34Medium-term monthly trend
Monthly40-Month SMA$50.90Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$64.00 support 1.28x 0 months ago
$56.00 support 1.05x 6 months ago
$45.00 support 1.81x 7 months ago

Historical Earnings Reactions (89 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.65% 0.00% 47.19% 16.82% -6.18%
1 Day 0.43% 0.00% 48.31% 26.09% -18.50%
1 Week -0.30% -0.70% 48.31% 37.68% -29.61%
2 Weeks -0.81% -1.52% 42.70% 39.86% -39.95%
1 Month 1.13% -0.88% 44.32% 54.30% -38.67%

Next earnings: May 5, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan0.2%45.5%22
Feb-2.4%45.5%22
Mar-0.1%50.0%22
Apr1.6%59.1%22
May1.9%59.1%22
Jun0.0%40.9%22
Jul6.0%68.2%22
Aug3.8%63.6%22
Sep3.5%45.5%22
Oct-7.0%31.8%22
Nov2.0%50.0%22
Dec9.7%50.0%22

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.10% 47.4% 1038
Tuesday 0.03% 45.4% 1138
Wednesday 0.23% 49.7% 1138
Thursday -0.09% 47.7% 1116
Friday 0.19% 47.7% 1111

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 116.3%

Insider Transactions — Smart Summary

Total insider ownership: 0.7%

12-Month Insider Activity Summary

Total Filings72
Net Value-$19.5M
Net Shares Change-250,057
% of Float-0.2%
C-Suite Filings57
Clusters Detected9

Key Insiders

NameTitleNet ValueFilingsActivity
Blum Robert I President and CEO -$2.8M 2 2 sell
Lee Sung EVP, Chief Financial Officer -$2.1M 2 1 sell
Callos Andrew EVP, Chief Commercial Officer -$1.3M 3 2 sell
Malik Fady Ibraham EVP Research and Development -$924,363.99 2 2 sell
PARSHALL B LYNNE -$306,050 1 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-06-05 – 2025-06-17 4 4 -$607,769.96 3 C-suite
2025-09-02 – 2025-09-15 5 4 -$1.0M 3 C-suite
2025-09-23 – 2025-10-07 5 3 -$1.2M 3 C-suite
2025-10-16 – 2025-10-30 4 3 -$927,665.1 3 C-suite
2025-11-19 – 2025-12-02 5 5 -$2.5M 1 C-suite
2026-03-02 – 2026-03-16 7 4 -$2.1M 6 C-suite
2026-03-18 – 2026-04-01 6 4 -$4.7M 6 C-suite
2026-04-08 – 2026-04-21 4 3 -$1.4M 4 C-suite
2026-04-29 – 2026-05-05 8 6 -$5.6M 6 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-03-18 Callos Andrew EVP, Chief Commercial Officer -$650,680.4 Transaction at $62.11, now +22.1%
2026-03-18 Blum Robert I President and CEO -$2.3M Transaction at $62.15, now +22.0%
2026-03-18 Malik Fady Ibraham EVP Research and Development -$747,850.95 Transaction at $62.15, now +22.0%
2026-03-18 Lee Sung EVP, Chief Financial Officer -$306,710.25 Transaction at $62.15, now +22.0%
2026-03-10 Callos Andrew EVP, Chief Commercial Officer -$156,779.04 Transaction at $60.72, now +24.9%
2026-03-10 Malik Fady Ibraham EVP Research and Development -$176,513.04 Transaction at $60.72, now +24.9%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Cytokinetics Inc (CYTK) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for CYTK on Trend Edge →