CYCN — Cyclerion Therapeutics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Cyclerion Therapeutics Inc

Cyclerion Therapeutics, Inc., a biopharmaceutical company, engages in the development of treatments for serious diseases serious diseases with novel sGC stimulators in both the central nervous system (CNS) and the periphery. The company is developing Olinciguat, an orally administered vascular soluble guanylate cyclase (sGC) stimulator, which is in Phase 2 clinical trial to treat cardiovascular diseases; and Praliciguat, a systemic sGC stimulator… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$3.20
Market Cap$13.3M
Float3.6M
Shares Outstanding4.3M
Price/Sales (TTM)6.69
vs. Analyst Target+150.0% to analyst PT
Profit Margin-264.73%
Operating Margin (TTM)-337.43%
Revenue (TTM)$2.0M
Dividend RateNone
Analyst Target Price$8.00 (1 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $2.3M -$77.8M -$54.1M -$80.6M
2021 $3.3M -$51.6M $3.3M -$53.8M
2022 $297,000 -$44.1M -$5.3M -$18.5M
2023 N/A -$5.3M N/A -$9.6M
2024 $2.0M -$3.1M $2.0M -$3.6M
2025 $2.1M -$3.5M $2.1M -$5.0M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $93,000 -$324,000
Sep 2025 $875,000 -$976,000
Dec 2025 $1.0M -$799,000
Mar 2026 N/A -$3.2M

Ownership & Float

Insider Ownership24.3%
Institutional Ownership4.2%
Short Float1.6%
% of All Funds Holding0.21%
Number of Funds Holding17

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$3.24Near-term / short-term trend
Weekly40-Week SMA$2.10Medium-term trend
Weekly80-Week SMA$2.54Cyclical trend (business cycle)
Weekly200-Week SMA$4.82Secular trend (multi-year)
Monthly10-Month SMA$2.03Near-term monthly trend
Monthly20-Month SMA$2.47Medium-term monthly trend
Monthly40-Month SMA$3.24Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$4.00 resistance 1.06x 14 months ago

Historical Earnings Reactions (28 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.76% -1.06% 39.29% 11.20% -6.57%
1 Day -3.57% -2.72% 39.29% 14.14% -23.39%
1 Week -1.48% 0.70% 50.00% 29.92% -31.52%
2 Weeks -3.57% -3.19% 42.86% 28.57% -47.08%
1 Month 5.14% 9.09% 67.86% 33.89% -46.35%

Next earnings: May 5, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.0%71.4%7
Feb-0.6%28.6%7
Mar-11.1%42.9%7
Apr8.3%37.5%8
May-2.5%28.6%7
Jun3.4%42.9%7
Jul2.8%28.6%7
Aug10.5%57.1%7
Sep-2.1%28.6%7
Oct-32.2%14.3%7
Nov1.6%28.6%7
Dec10.7%42.9%7

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.27% 44.7% 338
Tuesday -0.08% 46.0% 374
Wednesday 1.49% 41.4% 370
Thursday -0.38% 43.1% 362
Friday 0.09% 47.0% 362

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 4.2%

Insider Transactions — Smart Summary

Total insider ownership: 24.3%

Full insider transaction history and smart buy/sell sentiment summary available on Trend Edge.

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Cyclerion Therapeutics Inc (CYCN) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for CYCN on Trend Edge →