Stock analysis, trade plans, and proprietary indicators by Trend Edge.
About Crinetics Pharmaceuticals Inc
Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company's lead product candidate is Paltusotine, an oral selective nonpeptide somatostatin receptor type 2 agonist, which is in a Phase 3 clinical trial for the treatment of acromegaly and carcinoid syndrome associated with neuroen… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: July 18, 2018
Headquarters: 6055 Lusk Boulevard, San Diego, CA, United States, 92121
Founder-Led: Yes — Scott Struthers (Founder, President, CEO & Director), Stephen F. Betz (Co-Founder & Chief Scientific Officer)
Key Metrics
Current Price
$36.78
Market Cap
$3.82B
Float
95.6M
Shares Outstanding
105.4M
Price/Sales (TTM)
211.65
vs. Analyst Target
+126.1% to analyst PT
Operating Margin (TTM)
-1307.79%
Revenue (TTM)
$18.1M
Dividend Rate
None
Analyst Target Price
$83.14 (17 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$71,000
-$72.9M
$71,000
-$74.0M
2021
$1.1M
-$107M
$1.1M
-$107M
2022
$4.7M
-$160M
$4.7M
-$167M
2023
$4.0M
-$215M
$4.0M
-$222M
2024
$1.0M
-$298M
$1.0M
-$336M
2025
$7.7M
-$465M
$6.6M
-$513M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$1.0M
-$116M
Sep 2025
$143,000
-$130M
Dec 2025
$6.2M
-$123M
Mar 2026
$10.7M
-$128M
Ownership & Float
Insider Ownership
1.6%
Institutional Ownership
120.0%
Short Float
14.8%
% of All Funds Holding
2.74%
Number of Funds Holding
225
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$37.65
Near-term / short-term trend
Weekly
40-Week SMA
$41.90
Medium-term trend
Weekly
80-Week SMA
$39.24
Cyclical trend (business cycle)
Weekly
200-Week SMA
$34.49
Secular trend (multi-year)
Monthly
10-Month SMA
$41.12
Near-term monthly trend
Monthly
20-Month SMA
$40.32
Medium-term monthly trend
Monthly
40-Month SMA
$36.97
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$40.00
resistance
1.07x
1 months ago
$31.10
support
1.94x
7 months ago
$51.00
resistance
1.36x
15 months ago
Historical Earnings Reactions (32 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
1.15%
1.05%
68.75%
10.00%
-7.89%
1 Day
0.22%
-1.03%
43.75%
15.53%
-13.82%
1 Week
3.74%
2.24%
59.38%
25.40%
-29.96%
2 Weeks
2.26%
1.74%
53.13%
39.49%
-22.68%
1 Month
3.40%
0.00%
48.39%
50.75%
-27.22%
Next earnings: July 26, 2026 (60 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
-7.8%
50.0%
8
Feb
-2.2%
50.0%
8
Mar
-5.7%
25.0%
8
Apr
6.9%
62.5%
8
May
-1.8%
57.1%
7
Jun
-0.2%
57.1%
7
Jul
-2.5%
42.9%
7
Aug
5.5%
50.0%
8
Sep
10.5%
37.5%
8
Oct
0.7%
50.0%
8
Nov
10.5%
87.5%
8
Dec
3.7%
75.0%
8
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.04%
47.0%
370
Tuesday
0.35%
51.7%
406
Wednesday
0.30%
52.1%
403
Thursday
-0.05%
47.7%
396
Friday
-0.16%
45.6%
397
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 120.0%
Insider Transactions — Smart Summary
Total insider ownership: 1.6%
Founder-led management: Scott Struthers (Founder, President, CEO & Director), Stephen F. Betz (Co-Founder & Chief Scientific Officer)
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The analysis covers five layers:
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