80wk Downtrend — falling+below (sma 2.22 vs px 1.65)
200wk Downtrend — falling+below (sma 3.03 vs px 1.65)
RS Breakdown — momZ +0.49 · low 26w×0.77 · vs industry
About Codexis Inc
Codexis, Inc. provides technology solutions for therapeutics manufacturing, leveraging its proprietary CodeEvolver technology platform to discover, develop, enhance, and commercialize novel enzymes in the United States, Canada, Latin America, Europe, the Middle East, Africa, Australia, New Zealand, Southeast Asia, and China. The company develops its proprietary ECO Synthesis manufacturing platform to enable the scaled manufacture of RNAi therapeu… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: April 22, 2010
Headquarters: 200 Penobscot Drive, Redwood City, CA, United States, 94063
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$1.88
Near-term / short-term trend
Weekly
40-Week SMA
$1.90
Medium-term trend
Weekly
80-Week SMA
$2.22
Cyclical trend (business cycle)
Weekly
200-Week SMA
$3.03
Secular trend (multi-year)
Monthly
10-Month SMA
$1.81
Near-term monthly trend
Monthly
20-Month SMA
$2.27
Medium-term monthly trend
Monthly
40-Month SMA
$2.67
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$2.30
resistance
1.02x
0 months ago
$1.10
support
3.31x
4 months ago
Historical Earnings Reactions (66 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
0.78%
0.86%
53.03%
51.97%
-29.83%
1 Day
-0.46%
-0.24%
46.97%
34.65%
-44.74%
1 Week
-2.87%
-4.86%
40.91%
31.50%
-38.19%
2 Weeks
-3.81%
-3.33%
39.39%
30.71%
-43.16%
1 Month
0.61%
-1.93%
44.62%
86.61%
-49.28%
Next earnings: October 30, 2026 (63 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
3.1%
56.3%
16
Feb
-2.7%
31.3%
16
Mar
4.7%
56.3%
16
Apr
-3.0%
31.3%
16
May
-3.6%
35.3%
17
Jun
1.8%
47.1%
17
Jul
0.1%
47.1%
17
Aug
-5.4%
50.0%
16
Sep
-0.4%
43.8%
16
Oct
2.3%
43.8%
16
Nov
8.1%
50.0%
16
Dec
3.7%
62.5%
16
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
-0.04%
47.8%
770
Tuesday
0.20%
47.2%
845
Wednesday
-0.11%
44.3%
842
Thursday
0.20%
47.2%
827
Friday
-0.04%
46.3%
825
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 70.4%
Insider Transactions — Smart Summary
Total insider ownership: 6.2%
12-Month Insider Activity Summary
Total Filings
13
Net Value
-$59,107.804
Net Shares Change
-1,395,997
% of Float
-1.7%
C-Suite Filings
7
Clusters Detected
2
Key Insiders
Name
Title
Net Value
Filings
Activity
Opaleye Management Inc.
-$1.4M
2
2 sell
MOORE ALISON
Chief Technical Officer
-$20,630.283
2
2 sell
Erbez Georgia
Chief Financial Officer and Chief Business Officer
-$20,629.66
2
2 sell
Lutz Stefan
Chief Scientific Officer
-$17,847.861
3
3 sell
De Vre Raymond
-$6,173.85
1
1 sell
Transaction Clusters
Period
Filings
Insiders
Net Value
Seniority
2025-11-12 – 2025-11-25
4
3
+$469,335.166
2026-02-09 – 2026-02-09
3
3
-$13,259.222
3 C-suite
Significant Filings
Date
Insider
Title
Net Value
Price After
2026-06-11
De Vre Raymond
-$6,173.85
Transaction at $2.37, now -30.0%
2026-02-09
Erbez Georgia
Chief Financial Officer and Chief Business Officer
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The analysis covers five layers:
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