CDXS — Codexis Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates CDXS Bearish with a Setup Score of 35, net conviction 20, actionability 62. How the Setup Score works →

Total Setup Score35
Directional BiasBearish
Net Conviction20
Actionability62 (in range)

Key signals behind this score

About Codexis Inc

Codexis, Inc. provides technology solutions for therapeutics manufacturing, leveraging its proprietary CodeEvolver technology platform to discover, develop, enhance, and commercialize novel enzymes in the United States, Canada, Latin America, Europe, the Middle East, Africa, Australia, New Zealand, Southeast Asia, and China. The company develops its proprietary ECO Synthesis manufacturing platform to enable the scaled manufacture of RNAi therapeu… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$2.25
Market Cap$233M
Float73.5M
Shares Outstanding90.9M
P/E (Forward)149.25
Price/Sales (TTM)2.98
vs. Analyst Target+192.6% to analyst PT
Profit Margin-40.97%
Operating Margin (TTM)-52.75%
Revenue (TTM)$78.1M
Dividend RateNone
Analyst Target Price$6.58 (7 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $69.1M -$24.0M $55.3M -$19.4M
2021 $105M -$21.3M $82.5M -$16.8M
2022 $139M -$33.6M $101M -$26.3M
2023 $70.1M -$76.2M $57.3M -$49.3M
2024 $59.3M -$65.3M $43.1M -$53.4M
2025 $70.4M -$44.0M $61.0M -$33.9M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $15.3M -$13.3M
Sep 2025 $8.6M -$19.6M
Dec 2025 $38.9M $9.6M
Mar 2026 $15.2M -$8.7M

Ownership & Float

Insider Ownership7.4%
Institutional Ownership74.9%
Short Float4.4%
% of All Funds Holding1.50%
Number of Funds Holding123

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$2.48Near-term / short-term trend
Weekly40-Week SMA$1.98Medium-term trend
Weekly80-Week SMA$2.44Cyclical trend (business cycle)
Weekly200-Week SMA$3.15Secular trend (multi-year)
Monthly10-Month SMA$1.97Near-term monthly trend
Monthly20-Month SMA$2.46Medium-term monthly trend
Monthly40-Month SMA$2.75Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$1.10 support 3.31x 3 months ago

Historical Earnings Reactions (65 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 1.18% 0.92% 53.85% 51.97% -29.83%
1 Day -0.07% -0.07% 47.69% 34.65% -44.74%
1 Week -2.46% -4.65% 41.54% 31.50% -38.19%
2 Weeks -3.46% -3.17% 40.00% 30.71% -43.16%
1 Month 0.76% -1.39% 45.31% 86.61% -49.28%

Next earnings: August 12, 2026 (29 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.1%56.3%16
Feb-2.7%31.3%16
Mar4.7%56.3%16
Apr-3.0%31.3%16
May-3.6%35.3%17
Jun1.8%47.1%17
Jul2.5%50.0%16
Aug-5.4%50.0%16
Sep-0.4%43.8%16
Oct2.3%43.8%16
Nov8.1%50.0%16
Dec3.7%62.5%16

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.04% 47.7% 763
Tuesday 0.22% 47.6% 839
Wednesday -0.13% 44.1% 836
Thursday 0.20% 47.3% 821
Friday -0.01% 46.4% 819

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 74.9%

Insider Transactions — Smart Summary

Total insider ownership: 7.4%

12-Month Insider Activity Summary

Total Filings16
Net Value-$59,107.804
Net Shares Change-1,200,997
% of Float-1.6%
C-Suite Filings7
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
Opaleye Management Inc. +$538,080 3 3 buy
Erbez Georgia Chief Financial Officer and Chief Business Officer -$20,629.66 2 2 sell
Lutz Stefan Chief Scientific Officer -$17,847.861 3 3 sell
De Vre Raymond -$6,173.85 1 1 sell
MOORE ALISON President and CEO -$5,000.965 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-11-12 – 2025-11-25 4 3 +$469,335.166
2026-02-09 – 2026-02-09 3 3 -$13,259.222 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-06-11 De Vre Raymond -$6,173.85 Transaction at $2.37, now -5.1%
2026-02-09 Erbez Georgia Chief Financial Officer and Chief Business Officer -$5,000.965 Transaction at $1.31, now +72.1%
2026-02-25 Lutz Stefan Chief Scientific Officer -$6,641.06 Transaction at $1.13, now +98.6%
2026-02-09 MOORE ALISON President and CEO -$5,000.965 Transaction at $1.31, now +72.1%
2026-02-09 Lutz Stefan Chief Scientific Officer -$3,257.293 Transaction at $1.31, now +72.1%
2025-08-04 Opaleye Management Inc. +$227,919 Transaction at $2.68, now -16.1%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Codexis Inc (CDXS) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for CDXS on Trend Edge →