Short Squeeze Setup — velZ +0.45 · age 4w×1.00 · 14.17%
Seasonal Tailwind — november med 18% (mag 2/3) · posClose 75.00% (rel 2/3) · n12 ×0.5 = 4
About Crescent Biopharma, Inc.
Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Read full Trend Edge analysis →
Sector: Healthcare
Industry: Biotechnology
Exchange: NASDAQ
IPO Date: January 10, 2014
Headquarters: 300 Fifth Avenue, Waltham, MA, United States, 02451
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$16.69
Near-term / short-term trend
Weekly
40-Week SMA
$15.33
Medium-term trend
Weekly
80-Week SMA
$16.69
Cyclical trend (business cycle)
Weekly
200-Week SMA
$91.83
Secular trend (multi-year)
Monthly
10-Month SMA
$15.91
Near-term monthly trend
Monthly
20-Month SMA
$17.39
Medium-term monthly trend
Monthly
40-Month SMA
$74.72
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$11.40
support
1.50x
4 months ago
$9.50
support
1.67x
5 months ago
Historical Earnings Reactions (50 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
0.03%
-0.04%
44.00%
10.99%
-5.90%
1 Day
0.38%
-0.69%
48.00%
19.51%
-9.09%
1 Week
3.39%
0.46%
50.00%
153.66%
-65.73%
2 Weeks
6.78%
1.23%
54.00%
240.62%
-63.24%
1 Month
5.49%
-2.08%
48.98%
198.97%
-66.16%
Next earnings: October 18, 2026 (60 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
0.2%
41.7%
12
Feb
0.5%
53.8%
13
Mar
-0.9%
38.5%
13
Apr
-4.3%
46.2%
13
May
8.0%
46.2%
13
Jun
-3.1%
30.8%
13
Jul
-6.8%
30.8%
13
Aug
-5.3%
41.7%
12
Sep
-6.0%
16.7%
12
Oct
10.9%
50.0%
12
Nov
29.0%
75.0%
12
Dec
-3.1%
25.0%
12
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
-0.45%
44.6%
594
Tuesday
0.52%
43.6%
653
Wednesday
-0.27%
43.4%
650
Thursday
0.29%
45.7%
637
Friday
0.24%
46.6%
633
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 80.4%
Insider Transactions — Smart Summary
Total insider ownership: 0.4%
12-Month Insider Activity Summary
Total Filings
9
Net Value
-$1.2M
Net Shares Change
2,145,294
% of Float
8.1%
C-Suite Filings
7
Clusters Detected
1
Key Insiders
Name
Title
Net Value
Filings
Activity
Fairmount Funds Management LLC
+$30.6M
2
2 buy
Brumm Joshua T
Chief Executive Officer
-$761,066.95
1
N/A
McNeill Jonathan
President and COO
-$369,676.51
1
N/A
Pinkas Jan
Chief Scientific Officer
-$23,171.12
1
N/A
Im Ellie Eunkyung
Chief Medical Officer
-$21,929.81
1
N/A
Bispham Barbara Harlin
General Counsel and Corporate Secretary.
-$21,911.82
1
N/A
Scalzo Richard William
Chief Financial Officer
-$20,004.88
1
N/A
Lynch Ryan
Treasurer, Senior Vice President of Finance and Chief Accounting Officer.
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The analysis covers five layers:
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