CBIO — Crescent Biopharma, Inc.

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Crescent Biopharma, Inc.

Crescent Biopharma, Inc., a biotechnology company, researches and develops cancer therapy candidates in the United States. Its pipeline includes CR-001, which is in Phase 3 clinical trial, a proprietary anti-PD-1/anti-VEGF bispecific antibody to treat solid tumors; and CR-002, and CR-003. The company has a strategic partnership with Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$18.91
Market Cap$585M
Float14.6M
Shares Outstanding27.6M
Price/Sales (TTM)49.26
Operating Margin (TTM)-2380.08%
Revenue (TTM)$11.9M
Dividend RateNone

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $10.2M -$51.0M $10.2M -$51.2M
2021 $1.2M -$63.4M $1.2M -$63.2M
2022 $75,000 -$46.7M $75,000 -$47.2M
2023 $10,000 -$36.9M $10,000 -$39.1M
2024 N/A -$48.5M -$35,174 -$44.2M
2025 $10.8M -$154M $10.8M -$150M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$21.8M
Sep 2025 $30.6M -$24.6M
Dec 2025 $10.8M -$92.4M
Mar 2026 $1.0M -$23.3M

Ownership & Float

Insider Ownership5.8%
Institutional Ownership90.1%
Short Float16.4%
% of All Funds Holding0.67%
Number of Funds Holding55

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$18.54Near-term / short-term trend
Weekly40-Week SMA$13.92Medium-term trend
Weekly80-Week SMA$18.51Cyclical trend (business cycle)
Weekly200-Week SMA$95.32Secular trend (multi-year)
Monthly10-Month SMA$14.73Near-term monthly trend
Monthly20-Month SMA$19.89Medium-term monthly trend
Monthly40-Month SMA$83.95Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$11.40 support 1.50x 1 months ago
$9.50 support 1.67x 2 months ago
$180.00 resistance 5.88x 23 months ago
$306.00 resistance 3.09x 24 months ago

Historical Earnings Reactions (49 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.26% -0.24% 36.73% 8.48% -8.58%
1 Day -0.51% -1.02% 40.82% 19.51% -19.22%
1 Week 2.18% 0.00% 46.94% 153.66% -65.73%
2 Weeks 5.03% 1.00% 51.02% 162.16% -63.24%
1 Month 6.62% 0.29% 50.00% 202.21% -66.16%

Next earnings: May 13, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan0.2%41.7%12
Feb0.5%53.8%13
Mar-0.9%38.5%13
Apr-4.3%46.2%13
May9.3%50.0%12
Jun-2.3%33.3%12
Jul-5.8%33.3%12
Aug-5.3%41.7%12
Sep-6.0%16.7%12
Oct10.9%50.0%12
Nov29.0%75.0%12
Dec-3.1%25.0%12

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.45% 44.5% 582
Tuesday 0.53% 43.9% 640
Wednesday -0.25% 43.5% 637
Thursday 0.26% 45.2% 624
Friday 0.24% 46.6% 622

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 90.1%

Insider Transactions — Smart Summary

Total insider ownership: 5.8%

12-Month Insider Activity Summary

Total Filings1
Net Value+N/A
Net Shares Change1,360,000
% of Float9.3%
C-Suite Filings0
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
Fairmount Funds Management LLC +$18.2M 1 1 buy

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-12-08 Fairmount Funds Management LLC +$18.2M Transaction at $13.41, now +41.0%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Crescent Biopharma, Inc. (CBIO) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for CBIO on Trend Edge →