ASND — Ascendis Pharma AS

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates ASND Bullish with a Setup Score of 0, net conviction 66, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBullish
Net Conviction66
Actionability0 (extended)

Key signals behind this score

About Ascendis Pharma AS

Ascendis Pharma A/S, operates as a biopharmaceutical company that focuses on developing TransCon-based therapies for unmet medical needs in Europe, the United States, and internationally. The company offers SKYTROFA for treating pediatric patients with growth hormone deficiency; and YORVIPATH, a once-daily subcutaneous injection for the treatment of adults with chronic hypoparathyroidism. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$270.45
Market Cap$18.07B
Float62.1M
Shares Outstanding65.6M
P/E (Forward)17.24
P/E (TTM)32.14
Price/Sales (TTM)20.87
vs. Analyst Target+9.9% to analyst PT
Profit Margin57.28%
Operating Margin (TTM)10.06%
Revenue (TTM)$866M
Dividend RateNone
Analyst Target Price$297.24 (16 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $7.0M -$419M $7.0M -$408M
2021 $7.8M -$384M $4.3M -$365M
2022 $51.2M -$583M $39.0M -$529M
2023 $267M -$481M $222M -$411M
2024 $364M -$378M $319M -$290M
2025 $692M -$219M $589M -$110M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $158M -$38.9M
Sep 2025 $214M -$61.0M
Dec 2025 $245M -$33.2M
Mar 2026 $251M $640M

Ownership & Float

Insider Ownership0.8%
Institutional Ownership102.4%
Short Float3.2%
% of All Funds Holding3.07%
Number of Funds Holding252

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$241.54Near-term / short-term trend
Weekly40-Week SMA$223.70Medium-term trend
Weekly80-Week SMA$194.43Cyclical trend (business cycle)
Weekly200-Week SMA$148.19Secular trend (multi-year)
Monthly10-Month SMA$230.62Near-term monthly trend
Monthly20-Month SMA$197.97Medium-term monthly trend
Monthly40-Month SMA$158.05Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$225.00 support 1.45x 0 months ago
$172.00 support 1.13x 10 months ago
$157.00 support 1.13x 14 months ago
$128.00 support 1.04x 16 months ago
$125.00 support 1.10x 19 months ago

Historical Earnings Reactions (45 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.41% 0.06% 53.33% 5.49% -16.75%
1 Day 0.77% 0.97% 62.22% 10.16% -11.27%
1 Week 0.04% -0.91% 44.44% 22.69% -16.15%
2 Weeks 0.89% 0.37% 53.33% 23.93% -14.16%
1 Month 0.31% 2.56% 55.56% 18.71% -19.93%

Next earnings: August 6, 2026 (25 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.1%63.6%11
Feb5.1%58.3%12
Mar3.0%41.7%12
Apr-3.1%41.7%12
May-0.5%33.3%12
Jun3.5%66.7%12
Jul0.0%63.6%11
Aug8.5%72.7%11
Sep4.0%63.6%11
Oct-1.0%45.5%11
Nov4.7%81.8%11
Dec4.2%54.5%11

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.02% 44.8% 538
Tuesday 0.30% 51.2% 592
Wednesday 0.03% 49.4% 589
Thursday 0.21% 50.3% 580
Friday 0.13% 50.1% 575

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 102.4%

Insider Transactions — Smart Summary

Total insider ownership: 0.8%

Founder-led management: Jan Møller Mikkelsen (President and CEO)

12-Month Insider Activity Summary

Total Filings5
Net Value-$4.6M
Net Shares Change-18,210
% of Float-0.0%
C-Suite Filings3
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
JENSEN FLEMMING STEEN EVP & Product Supply and Quality -$4.6M 1 1 sell
BIENAIME JEAN JACQUES +$206,682.48 2 2 buy
SMITH SCOTT THOMAS EVP & Chief Financial Officer +$77,730 2 2 buy

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-06-02 SMITH SCOTT THOMAS EVP & Chief Financial Officer +$21,900 Transaction at $219.00, now +23.5%
2026-06-01 SMITH SCOTT THOMAS EVP & Chief Financial Officer +$55,830 Transaction at $223.32, now +21.1%
2026-06-01 BIENAIME JEAN JACQUES +$111,562 Transaction at $223.12, now +21.2%
2026-05-27 BIENAIME JEAN JACQUES +$95,120.48 Transaction at $237.80, now +13.7%
2026-05-12 JENSEN FLEMMING STEEN EVP & Product Supply and Quality -$4.6M Transaction at $238.49, now +13.4%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Ascendis Pharma AS (ASND) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ASND on Trend Edge →