ASMB — Assembly Biosciences Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates ASMB Bullish with a Setup Score of 43, net conviction 33, actionability 55. How the Setup Score works →

Total Setup Score43
Directional BiasBullish
Net Conviction33
Actionability55 (in range)

Key signals behind this score

About Assembly Biosciences Inc

Assembly Biosciences, Inc., a biotechnology company, develops therapeutic candidates for the treatment of viral diseases worldwide. Its pipeline includes long-acting helicase-primase inhibitors candidates, including ABI-5366 and ABI-1179, which are in Phase 1 clinical studies for recurrent genital herpes; and ABI-6250, an orally bioavailable hepatitis delta virus entry inhibitor that is in Phase 1a clinical study for the treatment of chronic hepa… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$27.40
Market Cap$552M
Float8.8M
Shares Outstanding19.8M
P/E (Forward)16.26
P/E (TTM)348.38
Price/Sales (TTM)7.77
vs. Analyst Target+82.5% to analyst PT
Profit Margin-8.98%
Operating Margin (TTM)-138.44%
Revenue (TTM)$71.1M
Dividend RateNone
Analyst Target Price$50.00 (2 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $79.1M -$62.2M -$22.2M -$58.4M
2021 $6.3M -$130M $6.3M -$90.6M
2022 N/A -$92.1M -$498,000 -$93.6M
2023 $7.2M -$61.2M -$41.7M -$60.7M
2024 $28.5M -$40.2M -$27.4M -$39.7M
2025 $72.3M -$6.1M $72.2M -$6.0M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $9.6M -$10.2M
Sep 2025 $10.8M -$9.2M
Dec 2025 $42.5M $22.1M
Mar 2026 $8.2M -$9.1M

Ownership & Float

Insider Ownership28.4%
Institutional Ownership48.4%
Short Float21.2%
% of All Funds Holding0.80%
Number of Funds Holding66

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$26.66Near-term / short-term trend
Weekly40-Week SMA$29.54Medium-term trend
Weekly80-Week SMA$22.98Cyclical trend (business cycle)
Weekly200-Week SMA$17.62Secular trend (multi-year)
Monthly10-Month SMA$29.57Near-term monthly trend
Monthly20-Month SMA$22.99Medium-term monthly trend
Monthly40-Month SMA$18.02Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$34.10 resistance 1.08x 5 months ago
$25.60 support 2.25x 8 months ago
$17.80 support 3.69x 10 months ago
$14.20 support 1.21x 12 months ago

Historical Earnings Reactions (62 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.89% 0.00% 43.55% 9.96% -60.38%
1 Day -1.37% -1.01% 37.10% 14.50% -69.37%
1 Week -1.66% -2.31% 45.16% 28.46% -64.65%
2 Weeks 0.23% -1.51% 46.77% 43.14% -65.79%
1 Month 2.01% -0.16% 49.18% 54.37% -62.20%

Next earnings: August 5, 2026 (24 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan2.3%56.3%16
Feb3.3%56.3%16
Mar-1.1%31.3%16
Apr1.4%37.5%16
May5.7%56.3%16
Jun-1.6%37.5%16
Jul-3.9%26.7%15
Aug3.0%53.3%15
Sep-3.3%33.3%15
Oct6.4%33.3%15
Nov-3.3%46.7%15
Dec-0.5%40.0%15

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.18% 46.2% 732
Tuesday 0.01% 43.8% 804
Wednesday 0.06% 49.1% 801
Thursday 0.05% 47.0% 787
Friday 0.29% 49.7% 783

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 48.4%

Insider Transactions — Smart Summary

Total insider ownership: 28.4%

12-Month Insider Activity Summary

Total Filings4
Net Value-$14,686.618
Net Shares Change2,327,866
% of Float26.4%
C-Suite Filings3
Clusters Detected0

Key Insiders

NameTitleNet ValueFilingsActivity
Bjorkquist Jeanette M PFO and PAO -$9,428.964 2 N/A
White Nicole S Chief Manufacturing Officer -$5,257.654 1 N/A
GILEAD SCIENCES, INC. +N/A 1 1 buy

Significant Filings

DateInsiderTitleNet ValuePrice After
2025-10-03 GILEAD SCIENCES, INC. +N/A N/A
2026-03-31 White Nicole S Chief Manufacturing Officer -$5,257.654 Transaction at $26.69, now +2.7%
2026-03-31 Bjorkquist Jeanette M PFO and PAO -$8,754.714 Transaction at $26.69, now +2.7%
2026-06-18 Bjorkquist Jeanette M PFO and PAO -$674.25 Transaction at $23.25, now +17.8%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Assembly Biosciences Inc (ASMB) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ASMB on Trend Edge →