ALXO — Alx Oncology Holdings 

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates ALXO Bullish with a Setup Score of 42, net conviction 43, actionability 42. How the Setup Score works →

Total Setup Score42
Directional BiasBullish
Net Conviction43
Actionability42 (in range)

Key signals behind this score

About Alx Oncology Holdings 

ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for cancer patients in the United States. The company's lead product candidate is Evorpacept, a CD47 blocking therapeutic biologic development as a combination therapy with other anti-cancer agents, including ASPEN-06, under phase 2 clinical study for treating Gastric/GEJ cancer. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$2.13
Market Cap$277M
Float77.5M
Shares Outstanding134.6M
Price/Sales (TTM)5,085.96
vs. Analyst Target+116.0% to analyst PT
Dividend RateNone
Analyst Target Price$4.60 (6 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $1.2M -$45.7M $107,000 -$43.5M
2021 N/A -$83.5M -$736,000 -$83.4M
2022 N/A -$123M -$1.5M -$127M
2023 N/A -$161M -$836,000 -$158M
2024 N/A -$135M -$872,000 -$132M
2025 N/A -$102M N/A -$99.4M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 N/A -$25.9M
Sep 2025 N/A -$22.1M
Dec 2025 N/A -$22.8M
Mar 2026 N/A -$17.9M

Ownership & Float

Insider Ownership0.9%
Institutional Ownership78.8%
Short Float3.3%
% of All Funds Holding0.79%
Number of Funds Holding65

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$1.89Near-term / short-term trend
Weekly40-Week SMA$1.73Medium-term trend
Weekly80-Week SMA$1.32Cyclical trend (business cycle)
Weekly200-Week SMA$5.35Secular trend (multi-year)
Monthly10-Month SMA$1.77Near-term monthly trend
Monthly20-Month SMA$1.38Medium-term monthly trend
Monthly40-Month SMA$4.46Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$0.60 support 1.82x 10 months ago
$3.20 resistance 2.29x 22 months ago
$10.60 resistance 1.41x 24 months ago

Historical Earnings Reactions (24 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.30% -0.07% 50.00% 26.34% -13.05%
1 Day -2.11% 0.04% 50.00% 7.48% -19.08%
1 Week -0.92% -4.29% 33.33% 48.12% -36.64%
2 Weeks -1.29% -6.91% 41.67% 95.12% -46.03%
1 Month -0.63% -6.16% 43.48% 70.73% -61.37%

Next earnings: August 11, 2026 (30 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.37% 49.3% 280
Tuesday -0.00% 46.1% 310
Wednesday 0.08% 47.7% 308
Thursday -0.36% 47.3% 300
Friday 0.00% 47.2% 299

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 78.8%

Insider Transactions — Smart Summary

Total insider ownership: 0.9%

Founder-led management: Corey Goodman (Executive Chairman)

12-Month Insider Activity Summary

Total Filings10
Net Value+$118,661.33
Net Shares Change3,329,845
% of Float4.3%
C-Suite Filings9
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
GOODMAN COREY S +$5.0M 1 1 buy
Lettmann Jason CHIEF EXECUTIVE OFFICER +$71,113.085 3 1 buy, 2 sell
Shantharam Harish Chief Financial Officer +$58,402.5 1 1 buy
Pinto Shelly SVP, FINANCE AND CAO -$7,990.094 4 4 sell
Wong Shelly SVP, FINANCE AND CAO -$2,864.16 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-19 – 2025-08-20 3 3 +$56,485.783 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-07-06 Wong Shelly SVP, FINANCE AND CAO -$2,864.16 Transaction at $2.04, now +4.4%
2026-02-04 GOODMAN COREY S +$5.0M Transaction at $1.57, now +35.7%
2025-09-18 Lettmann Jason CHIEF EXECUTIVE OFFICER +$99,353.388 Transaction at $1.08, now +97.7%
2025-08-20 Shantharam Harish Chief Financial Officer +$58,402.5 Transaction at $0.78, now +173.5%
2026-03-23 Lettmann Jason CHIEF EXECUTIVE OFFICER -$26,714.87 Transaction at $2.17, now -1.8%
2026-03-23 Pinto Shelly SVP, FINANCE AND CAO -$1,959.51 Transaction at $2.17, now -1.8%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Alx Oncology Holdings  (ALXO) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ALXO on Trend Edge →