AGEN — Agenus Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Agenus Inc

Agenus Inc., a clinical-stage biotechnology company, discovers and develops immunotherapies for cancer and infectious diseases in the United States and internationally. It offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies. It develops QS-21 Stimulon adjuvant, a saponin-based vaccine adjuvant. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$3.58
Market Cap$149M
Float38.6M
Shares Outstanding41.6M
P/E (Forward)1.74
P/E (TTM)1.75
Price/Sales (TTM)1.20
vs. Analyst Target+333.0% to analyst PT
Profit Margin52.16%
Operating Margin (TTM)44.62%
Revenue (TTM)$124M
Dividend RateNone
Analyst Target Price$15.50 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $88.2M -$181M -$56.8M -$115M
2021 $296M -$23.9M $114M $43.8M
2022 $98.0M -$220M -$99.2M -$162M
2023 $156M -$246M -$81.4M -$146M
2024 $103M -$227M -$52.6M -$101M
2025 $114M $115,000 $33.8M $62.2M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $25.7M -$28.0M
Sep 2025 $30.2M $63.9M
Dec 2025 $34.2M -$10.6M
Mar 2026 $33.7M $39.2M

Ownership & Float

Insider Ownership6.7%
Institutional Ownership24.8%
Short Float11.4%
% of All Funds Holding1.06%
Number of Funds Holding82

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$3.74Near-term / short-term trend
Weekly40-Week SMA$3.78Medium-term trend
Weekly80-Week SMA$3.69Cyclical trend (business cycle)
Weekly200-Week SMA$17.45Secular trend (multi-year)
Monthly10-Month SMA$3.67Near-term monthly trend
Monthly20-Month SMA$3.58Medium-term monthly trend
Monthly40-Month SMA$11.59Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$1.60 support 1.40x 12 months ago
$16.70 resistance 1.87x 21 months ago

Historical Earnings Reactions (104 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.02% 0.00% 45.19% 13.82% -8.39%
1 Day -0.12% -0.57% 47.12% 21.28% -17.21%
1 Week -0.72% -2.00% 43.27% 57.32% -28.68%
2 Weeks 0.04% -1.43% 41.35% 84.42% -36.70%
1 Month 3.27% -1.09% 41.35% 228.17% -58.20%

Next earnings: May 11, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan5.0%53.8%26
Feb1.0%38.5%26
Mar-3.7%37.0%27
Apr7.7%55.6%27
May4.0%50.0%26
Jun8.5%57.7%26
Jul-2.0%50.0%26
Aug-2.5%30.8%26
Sep-7.0%19.2%26
Oct-7.9%34.6%26
Nov4.5%53.8%26
Dec-5.8%19.2%26

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.18% 45.2% 1239
Tuesday 0.21% 44.6% 1354
Wednesday -0.01% 44.3% 1355
Thursday -0.17% 44.6% 1329
Friday -0.07% 43.9% 1325

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 24.8%

Insider Transactions — Smart Summary

Total insider ownership: 6.7%

Founder-led management: Garo H. Armen (Head of Investor Relations & Corporate Development)

Full insider transaction history and smart buy/sell sentiment summary available on Trend Edge.

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Agenus Inc (AGEN) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for AGEN on Trend Edge →