ADAG — Adagene Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Adagene Inc

Adagene Inc., a clinical stage biotechnology company, engages in the research, development, and production of monoclonal antibody drugs for cancers in the People's Republic of China. Its lead product candidate is the ADG126, a masked fully-human anti-CTLA-4 mAb which is in phase 1b/2 clinical development for the treatment of cancer. The company also develops ADG116, a fully human anti-CTLA-4 antibody generated using NEObody technology, which is i… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$4.00
Market Cap$228M
Float41.4M
Shares Outstanding66.1M
Price/Sales (TTM)29.72
vs. Analyst Target+135.0% to analyst PT
Profit Margin-229.56%
Operating Margin (TTM)-74.96%
Revenue (TTM)$7.7M
Dividend RateNone
Analyst Target Price$9.40 (3 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $480,000 -$16.4M $480,000 -$41.3M
2021 $10.2M -$73.2M $10.2M -$70.0M
2022 $9.3M -$80.0M $9.3M -$77.4M
2023 $18.1M -$18.9M $18.1M -$15.0M
2024 $103,204 -$33.4M -$823,044 -$31.7M
2025 $7.7M -$17.6M $7.7M -$16.9M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2024 N/A -$8.5M
Dec 2024 $103,204 -$24.9M
Jun 2025 N/A -$13.5M
Mar 2026 $7.7M -$4.1M

Ownership & Float

Insider Ownership21.2%
Institutional Ownership20.9%
Short Float1.6%
% of All Funds Holding0.26%
Number of Funds Holding21

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$3.80Near-term / short-term trend
Weekly40-Week SMA$2.63Medium-term trend
Weekly80-Week SMA$2.25Cyclical trend (business cycle)
Weekly200-Week SMA$2.07Secular trend (multi-year)
Monthly10-Month SMA$2.71Near-term monthly trend
Monthly20-Month SMA$2.36Medium-term monthly trend
Monthly40-Month SMA$2.22Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$3.00 support 1.89x 1 months ago
$1.90 support 2.00x 3 months ago
$1.80 support 3.05x 5 months ago

Historical Earnings Reactions (21 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.57% -0.40% 28.57% 9.02% -14.32%
1 Day 0.22% 0.00% 47.62% 19.05% -13.61%
1 Week 0.69% 2.00% 57.14% 22.45% -19.33%
2 Weeks -2.92% -4.11% 42.86% 22.22% -25.40%
1 Month -2.02% -4.81% 33.33% 44.56% -23.73%

Next earnings: June 20, 2026 (23 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.24% 41.5% 246
Tuesday -0.01% 44.4% 275
Wednesday 0.19% 45.4% 273
Thursday 0.19% 42.9% 266
Friday -0.17% 41.0% 268

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 20.9%

Insider Transactions — Smart Summary

Total insider ownership: 21.2%

Founder-led management: Pei Zhi Luo (Chairman, CEO & President of R&D)

Full insider transaction history and smart buy/sell sentiment summary available on Trend Edge.

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Adagene Inc (ADAG) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ADAG on Trend Edge →