ABEO — Abeona Therapeutics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates ABEO Bullish with a Setup Score of 45, net conviction 33, actionability 62. How the Setup Score works →

Total Setup Score45
Directional BiasBullish
Net Conviction33
Actionability62 (in range)

Key signals behind this score

About Abeona Therapeutics Inc

Abeona Therapeutics Inc., a commercial-stage biopharmaceutical company, develops gene and cell therapies for life-threatening diseases in the United States. It develops ZEVASKYN, an autologous, cell-based gene therapy for the treatment of patients with recessive dystrophic epidermolysis bullosa. The company also develops ABO-503 to treat X-linked retinoschisis; ABO-504 for the treatment of stargardt disease; and ABO-505 to treat autosomal dominan… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$4.94
Market Cap$284M
Float36.9M
Shares Outstanding57.2M
P/E (Forward)18.66
Price/Sales (TTM)11.11
vs. Analyst Target+282.1% to analyst PT
Profit Margin-246.42%
Operating Margin (TTM)-119.97%
Revenue (TTM)$25.5M
Dividend RateNone
Analyst Target Price$18.88 (7 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $10.0M -$84.2M $10.0M -$74.5M
2021 $3.0M -$84.9M $3.0M -$76.8M
2022 $1.4M -$39.7M $964,000 -$34.4M
2023 $3.5M -$54.2M $1.9M -$50.6M
2024 N/A -$63.7M -$2.9M -$56.6M
2025 $5.8M $71.2M $4.3M $78.6M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 N/A -$5.2M
Dec 2025 $5.4M -$20.5M
Mar 2026 $8.7M -$17.1M
Jun 2026 $11.4M -$20.2M

Ownership & Float

Insider Ownership11.0%
Institutional Ownership74.9%
Short Float41.1%
% of All Funds Holding1.44%
Number of Funds Holding127

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$5.76Near-term / short-term trend
Weekly40-Week SMA$5.53Medium-term trend
Weekly80-Week SMA$5.61Cyclical trend (business cycle)
Weekly200-Week SMA$5.06Secular trend (multi-year)
Monthly10-Month SMA$5.46Near-term monthly trend
Monthly20-Month SMA$5.57Medium-term monthly trend
Monthly40-Month SMA$5.35Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$6.80 resistance 1.04x 12 months ago

Historical Earnings Reactions (105 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.24% 0.00% 32.38% 46.67% -15.52%
1 Day -0.46% 0.00% 40.00% 46.67% -27.27%
1 Week 0.00% 0.00% 40.00% 80.00% -30.68%
2 Weeks 3.21% 0.00% 48.57% 64.00% -34.07%
1 Month 5.23% 0.33% 50.00% 132.43% -68.13%

Next earnings: November 11, 2026 (32 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan11.8%56.5%46
Feb5.4%39.1%46
Mar-2.2%37.0%46
Apr0.4%50.0%46
May2.1%37.0%46
Jun-3.3%32.6%46
Jul-3.3%32.6%46
Aug-0.9%41.3%46
Sep2.0%43.5%46
Oct4.0%50.0%46
Nov-1.3%32.6%46
Dec-3.0%34.8%46

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.14% 34.1% 2194
Tuesday -0.20% 34.1% 2380
Wednesday 0.15% 35.8% 2378
Thursday 0.33% 37.9% 2332
Friday 0.40% 37.4% 2318

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 74.9%

Insider Transactions — Smart Summary

Total insider ownership: 11.0%

12-Month Insider Activity Summary

Total Filings34
Net Value-$2.6M
Net Shares Change-562,014
% of Float-1.5%
C-Suite Filings22
Clusters Detected5

Key Insiders

NameTitleNet ValueFilingsActivity
Seshadri Vishwas Chief Executive Officer -$574,420.658 2 2 sell
Vazzano Joseph Walter Chief Financial Officer -$230,293.316 3 3 sell
O'Malley Brendan M. SVP, Chief Legal Officer -$118,594.306 2 2 sell
Vasanthavada Madhav Chief Commercial Officer -$113,057.153 2 2 sell
Alvino Mark -$87,966 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2026-01-21 – 2026-02-02 10 9 -$1.0M 4 C-suite
2026-05-11 – 2026-05-22 3 3 -$213,172.14 1 C-suite
2026-06-09 – 2026-06-15 5 5 -$782,050.062 4 C-suite
2026-07-02 – 2026-07-09 5 5 -$883,370.496 4 C-suite
2026-09-29 – 2026-09-29 4 4 -$208,430.597 4 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-09-29 Vazzano Joseph Walter Chief Financial Officer -$47,385.12 Transaction at $5.16, now -4.2%
2026-09-29 Vasanthavada Madhav Chief Commercial Officer -$25,272.751 Transaction at $5.16, now -4.2%
2026-09-29 Seshadri Vishwas Chief Executive Officer -$101,091.005 Transaction at $5.16, now -4.2%
2026-09-29 O'Malley Brendan M. SVP, Chief Legal Officer -$34,681.721 Transaction at $5.16, now -4.2%
2026-09-01 Alvino Mark -$87,966 Transaction at $5.86, now -15.8%
2026-07-22 Vazzano Joseph Walter Chief Financial Officer -$9,651.34 Transaction at $6.53, now -24.3%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Abeona Therapeutics Inc (ABEO) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ABEO on Trend Edge →