KALV — Kalvista Pharmaceuticals Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Kalvista Pharmaceuticals Inc

KalVista Pharmaceuticals, Inc., a biopharmaceutical company, develops oral therapies for individuals for rare diseases with unmet needs. Its lead product candidate is EKTERLY, a fast-acting potent inhibitor of plasma kallikrein for the treatment of acute attacks of hereditary angioedema (HAE). The company is also developing is developing an orally disintegrating tablet formulation; KONFIDENT-KID for pediatric use with HAE; KONFIDENT; and KONFIDEN… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$26.79
Market Cap$1.43B
Float33.3M
Shares Outstanding53.2M
P/E (Forward)25.25
Price/Sales (TTM)12.45
vs. Analyst Target+6.8% to analyst PT
Profit Margin-118.74%
Operating Margin (TTM)-57.37%
Revenue (TTM)$114M
Dividend RateNone
Analyst Target Price$28.60 (10 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2021 $12.7M -$46.2M -$41.3M -$57.4M
2022 N/A -$82.3M -$743,000 -$80.7M
2023 N/A -$92.9M -$802,000 -$94.4M
2024 N/A -$127M -$86.2M -$134M
2025 N/A -$183M -$941,000 -$173M
2026 $73.6M -$164M $67.5M -$170M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jul 2025 $1.4M -$60.1M
Oct 2025 $40.9M -$23.5M
Jan 2026 $40.9M -$23.5M
Apr 2026 $59.9M -$5.4M

Ownership & Float

Insider Ownership1.7%
Institutional Ownership137.2%
Short Float45.6%
% of All Funds Holding2.06%
Number of Funds Holding169

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$23.24Near-term / short-term trend
Weekly40-Week SMA$16.60Medium-term trend
Weekly80-Week SMA$13.98Cyclical trend (business cycle)
Weekly200-Week SMA$11.80Secular trend (multi-year)
Monthly10-Month SMA$17.26Near-term monthly trend
Monthly20-Month SMA$14.19Medium-term monthly trend
Monthly40-Month SMA$12.54Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$20.70 support 3.08x 0 months ago
$16.00 support 1.03x 1 months ago
$14.30 support 1.23x 4 months ago
$10.90 support 1.28x 5 months ago
$8.80 support 1.15x 14 months ago

Historical Earnings Reactions (45 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.01% 0.00% 42.22% 4.59% -4.06%
1 Day -0.74% -0.25% 44.44% 10.56% -14.81%
1 Week 0.08% -0.77% 44.44% 45.13% -44.23%
2 Weeks -0.21% -4.27% 35.56% 53.98% -29.90%
1 Month 1.16% -8.39% 36.36% 93.98% -70.90%

Next earnings: December 4, 2025

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-2.0%36.4%11
Feb8.4%54.5%11
Mar-2.4%54.5%11
Apr6.7%54.5%11
May5.7%54.5%11
Jun-4.5%45.5%11
Jul1.2%45.5%11
Aug9.1%45.5%11
Sep-8.7%18.2%11
Oct2.0%45.5%11
Nov8.2%63.6%11
Dec3.6%45.5%11

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.05% 46.8% 523
Tuesday -0.17% 44.4% 577
Wednesday -0.02% 49.4% 573
Thursday 0.22% 49.7% 563
Friday 0.47% 51.1% 562

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 137.2%

Insider Transactions — Smart Summary

Total insider ownership: 1.7%

12-Month Insider Activity Summary

Total Filings51
Net Value-$4.1M
Net Shares Change96,880
% of Float0.3%
C-Suite Filings50
Clusters Detected5

Key Insiders

NameTitleNet ValueFilingsActivity
Venrock Healthcare Capital Partners III, L.P. -$3.7M 1 1 sell
Palleiko Benjamin L CHIEF EXECUTIVE OFFICER -$292,646.354 1 N/A
Sweeny Nicole Chief Commercial Officer -$240,527.356 5 N/A
Piekos Brian Chief Financial Officer -$105,031.258 3 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-19 – 2025-08-26 10 4 -$448,702.301 10 C-suite
2025-11-13 – 2025-11-26 8 4 -$523,262.231 8 C-suite
2026-02-13 – 2026-02-24 9 5 -$498,903.164 9 C-suite
2026-04-20 – 2026-04-20 4 4 -$322,652.148 4 C-suite
2026-05-13 – 2026-05-27 12 5 -$846,129.677 12 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-03-27 Venrock Healthcare Capital Partners III, L.P. -$3.7M Transaction at $17.20, now +55.8%
2026-05-26 Piekos Brian Chief Financial Officer -$39,881.972 Transaction at $26.78, now +0.0%
2026-04-20 Piekos Brian Chief Financial Officer -$37,642.751 Transaction at $20.22, now +32.5%
2026-05-27 Sweeny Nicole Chief Commercial Officer -$39,872.144 Transaction at $26.78, now +0.0%
2026-05-26 Sweeny Nicole Chief Commercial Officer -$49,845.768 Transaction at $26.78, now +0.0%
2026-04-20 Sweeny Nicole Chief Commercial Officer -$37,642.751 Transaction at $20.22, now +32.5%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Kalvista Pharmaceuticals Inc (KALV) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for KALV on Trend Edge →