PSNL — Personalis Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates PSNL Bullish with a Setup Score of 41, net conviction 47, actionability 35. How the Setup Score works →

Total Setup Score41
Directional BiasBullish
Net Conviction47
Actionability35 (in range)

Key signals behind this score

About Personalis Inc

Personalis, Inc. develops, markets, and sells advanced cancer genomic tests and services in the United States and internationally. The company offers NeXT Personal, a tumor-informed liquid biopsy test for detection of minimal residual disease (MRD), therapy response and recurrence monitoring in solid tumor cancers; and ImmunoID NeXT, a tissue-based service that combines whole exome and whole transcriptome sequencing data with advanced analytics t… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$16.00
Market Cap$1.72B
Float86.4M
Shares Outstanding106.8M
Price/Sales (TTM)24.61
vs. Analyst Target-5.2% to analyst PT
Profit Margin-153.84%
Operating Margin (TTM)-150.25%
Revenue (TTM)$69.7M
Dividend RateNone
Analyst Target Price$15.17 (5 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $78.6M -$41.3M $20.1M -$35.5M
2021 $85.5M -$65.2M $31.7M -$59.0M
2022 $65.0M -$113M $13.3M -$105M
2023 $73.5M -$108M $18.2M -$96.8M
2024 $84.6M -$81.3M $26.8M -$70.3M
2025 $69.6M -$81.3M $15.8M -$71.0M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $14.5M -$21.7M
Dec 2025 $17.3M -$23.8M
Mar 2026 $15.5M -$30.0M
Jun 2026 $22.4M -$31.7M

Ownership & Float

Insider Ownership26.1%
Institutional Ownership66.8%
Short Float9.7%
% of All Funds Holding1.81%
Number of Funds Holding159

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$16.22Near-term / short-term trend
Weekly40-Week SMA$10.91Medium-term trend
Weekly80-Week SMA$8.66Cyclical trend (business cycle)
Weekly200-Week SMA$5.11Secular trend (multi-year)
Monthly10-Month SMA$11.68Near-term monthly trend
Monthly20-Month SMA$9.03Medium-term monthly trend
Monthly40-Month SMA$5.93Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$12.50 support 1.53x 1 months ago
$5.60 support 1.72x 4 months ago
$4.70 support 1.58x 15 months ago
$3.50 support 2.42x 25 months ago

Historical Earnings Reactions (30 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.66% 0.31% 50.00% 19.79% -26.15%
1 Day 0.18% 0.46% 53.33% 21.50% -22.58%
1 Week 0.44% -4.95% 43.33% 76.04% -23.45%
2 Weeks 1.09% -1.47% 40.00% 98.26% -39.43%
1 Month 6.97% 4.80% 53.33% 100.35% -45.33%

Next earnings: November 3, 2026 (22 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-3.5%57.1%7
Feb-4.0%28.6%7
Mar-15.3%0.0%7
Apr-3.9%42.9%7
May10.4%42.9%7
Jun9.0%71.4%7
Jul23.6%50.0%8
Aug10.8%62.5%8
Sep-6.6%12.5%8
Oct-0.3%42.9%7
Nov1.5%42.9%7
Dec13.7%71.4%7

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.01% 48.5% 344
Tuesday 0.01% 45.4% 379
Wednesday 0.05% 46.9% 375
Thursday 0.38% 46.9% 367
Friday 0.30% 48.2% 367

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 66.8%

Insider Transactions — Smart Summary

Total insider ownership: 26.1%

12-Month Insider Activity Summary

Total Filings16
Net Value-$6.0M
Net Shares Change274,199
% of Float0.3%
C-Suite Filings15
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
Hall Christopher M Chief Executive Officer -$2.9M 4 2 sell
Tempus AI, Inc. +$2.7M 1 1 buy
Chen Richard President and CMO -$1.3M 2 1 sell
Tachibana Aaron CFO AND COO -$90,784.58 2 1 sell
Moore Stephen Michael SVP and Chief Legal Officer -$33,542.96 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2026-09-22 – 2026-09-22 4 4 -$266,916.32 4 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-09-22 Moore Stephen Michael SVP and Chief Legal Officer -$33,542.96 Transaction at $16.22, now -1.4%
2026-09-22 Hall Christopher M Chief Executive Officer -$120,984.98 Transaction at $16.22, now -1.4%
2026-09-22 Chen Richard President and CMO -$64,847.56 Transaction at $16.22, now -1.4%
2026-09-22 Tachibana Aaron CFO AND COO -$47,540.82 Transaction at $16.22, now -1.4%
2026-02-13 Tempus AI, Inc. +$2.7M Transaction at $8.55, now +87.1%
2025-11-05 Hall Christopher M PRESIDENT AND CEO -$266,211.88 Transaction at $8.99, now +78.0%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Personalis Inc (PSNL) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for PSNL on Trend Edge →