GH — Guardant Health Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Guardant Health Inc

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; an… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$119.85
Market Cap$15.25B
Float127.6M
Shares Outstanding132.6M
Price/Sales (TTM)14.11
vs. Analyst Target+8.9% to analyst PT
Profit Margin-40.10%
Operating Margin (TTM)-40.23%
Revenue (TTM)$1.08B
Dividend RateNone
Analyst Target Price$130.52 (24 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $287M -$254M $194M -$225M
2021 $374M -$406M $251M -$360M
2022 $450M -$655M $293M -$615M
2023 $564M -$479M $337M -$433M
2024 $739M -$436M $449M -$390M
2025 $982M -$416M $633M -$374M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $232M -$99.9M
Sep 2025 $265M -$92.7M
Dec 2025 $281M -$128M
Mar 2026 $302M -$112M

Ownership & Float

Insider Ownership4.1%
Institutional Ownership105.7%
Short Float10.0%
% of All Funds Holding5.50%
Number of Funds Holding452

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$95.33Near-term / short-term trend
Weekly40-Week SMA$91.07Medium-term trend
Weekly80-Week SMA$67.32Cyclical trend (business cycle)
Weekly200-Week SMA$45.50Secular trend (multi-year)
Monthly10-Month SMA$94.07Near-term monthly trend
Monthly20-Month SMA$67.09Medium-term monthly trend
Monthly40-Month SMA$47.22Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$63.00 support 1.16x 6 months ago
$41.00 support 1.25x 8 months ago
$31.30 support 1.15x 15 months ago
$22.30 support 1.08x 17 months ago
$18.10 support 1.50x 23 months ago

Historical Earnings Reactions (31 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 3.00% 0.12% 51.61% 28.07% -7.91%
1 Day 3.84% 3.47% 61.29% 27.87% -22.48%
1 Week 4.68% 6.05% 64.52% 33.18% -29.20%
2 Weeks 5.39% 4.14% 54.84% 37.12% -27.50%
1 Month 7.46% 1.46% 53.33% 63.79% -24.00%

Next earnings: July 26, 2026 (59 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan7.1%62.5%8
Feb3.4%25.0%8
Mar-2.3%50.0%8
Apr-2.3%37.5%8
May6.5%57.1%7
Jun8.2%71.4%7
Jul5.1%71.4%7
Aug8.3%57.1%7
Sep-6.6%28.6%7
Oct3.0%28.6%7
Nov13.0%75.0%8
Dec-6.6%50.0%8

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.17% 49.2% 360
Tuesday 0.16% 49.9% 395
Wednesday 0.34% 48.5% 392
Thursday 0.37% 50.8% 384
Friday 0.08% 49.2% 386

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 105.7%

Insider Transactions — Smart Summary

Total insider ownership: 4.1%

Founder-led management: Helmy Eltoukhy (Co-Chief Executive Officer and Chairman), AmirAli Talasaz (Co-Chief Executive Officer and Director)

12-Month Insider Activity Summary

Total Filings49
Net Value-$104M
Net Shares Change-1,111,215
% of Float-0.9%
C-Suite Filings22
Clusters Detected9

Key Insiders

NameTitleNet ValueFilingsActivity
Talasaz AmirAli Co-Chief Executive Officer -$10.5M 1 1 sell
Bell Michael Brian Chief Financial Officer -$7.5M 2 2 sell
Freeman Chris Chief Commercial Officer -$3.2M 1 1 sell
Chudova Darya Chief Technology Officer -$3.0M 2 3 sell
Kalia Kumud Chief Information Officer -$2.2M 1 1 sell
CLARK IAN T -$735,048.526 1 1 sell
Hidalgo Medina Manuel -$187,760.415 2 2 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-06-03 – 2025-06-16 5 4 -$6.5M 2 C-suite
2025-06-20 – 2025-07-02 4 4 -$6.3M 1 C-suite
2025-08-20 – 2025-09-03 4 4 -$138,474.84 1 C-suite
2025-09-11 – 2025-09-17 4 4 -$18.0M 1 C-suite
2025-11-10 – 2025-11-20 3 3 -$987,260.2 1 C-suite
2025-12-02 – 2025-12-10 8 8 -$29.8M 6 C-suite
2025-12-17 – 2025-12-18 3 3 -$10.0M 2 C-suite
2026-03-05 – 2026-03-19 4 4 -$3.2M 2 C-suite
2026-05-13 – 2026-05-22 6 5 -$31.1M 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-05-22 CLARK IAN T -$735,048.526 Transaction at $106.90, now +12.1%
2026-03-05 Kalia Kumud Chief Information Officer -$2.2M Transaction at $66.40, now +80.5%
2025-12-10 Chudova Darya Chief Technology Officer -$2.4M Transaction at $105.52, now +13.6%
2026-03-17 Bell Michael Brian Chief Financial Officer -$894,848.37 Transaction at $86.26, now +38.9%
2026-05-22 Hidalgo Medina Manuel -$101,313.875 Transaction at $69.82, now +71.7%
2026-03-09 Hidalgo Medina Manuel -$86,446.54 Transaction at $62.04, now +93.2%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Guardant Health Inc (GH) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for GH on Trend Edge →