GH — Guardant Health Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates GH Bullish with a Setup Score of 0, net conviction 42, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBullish
Net Conviction42
Actionability0 (extended)

Key signals behind this score

About Guardant Health Inc

Guardant Health, Inc., a precision oncology company, provides blood and tissue tests, and data sets in the United States and internationally. The company offers Guardant360 CDx test, a liquid biopsy test for tumor mutation profiling; Guardant360 Liquid test, which measures 740+ genes and supports all guideline-recommended biomarkers; Guardant Reveal test, a blood test that utilizes circulating tumor DNA to detect cancer at the molecular level; an… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$160.05
Market Cap$21.76B
Float127.8M
Shares Outstanding132.6M
Price/Sales (TTM)20.14
vs. Analyst Target-4.7% to analyst PT
Profit Margin-40.10%
Operating Margin (TTM)-40.23%
Revenue (TTM)$1.08B
Dividend RateNone
Analyst Target Price$152.54 (23 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $287M -$254M $194M -$225M
2021 $374M -$406M $251M -$360M
2022 $450M -$655M $293M -$615M
2023 $564M -$479M $337M -$433M
2024 $739M -$436M $449M -$390M
2025 $982M -$416M $633M -$374M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $232M -$99.9M
Sep 2025 $265M -$92.7M
Dec 2025 $281M -$128M
Mar 2026 $302M -$112M

Ownership & Float

Insider Ownership4.0%
Institutional Ownership106.0%
Short Float10.2%
% of All Funds Holding5.50%
Number of Funds Holding452

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$130.55Near-term / short-term trend
Weekly40-Week SMA$103.86Medium-term trend
Weekly80-Week SMA$75.75Cyclical trend (business cycle)
Weekly200-Week SMA$48.30Secular trend (multi-year)
Monthly10-Month SMA$113.07Near-term monthly trend
Monthly20-Month SMA$80.21Medium-term monthly trend
Monthly40-Month SMA$53.86Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$63.00 support 1.16x 8 months ago
$41.00 support 1.25x 10 months ago
$31.30 support 1.15x 17 months ago
$22.30 support 1.08x 19 months ago
$18.10 support 1.50x 25 months ago

Historical Earnings Reactions (31 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 3.00% 0.12% 51.61% 28.07% -7.91%
1 Day 3.84% 3.47% 61.29% 27.87% -22.48%
1 Week 4.68% 6.05% 64.52% 33.18% -29.20%
2 Weeks 5.39% 4.14% 54.84% 37.12% -27.50%
1 Month 7.46% 1.46% 53.33% 63.79% -24.00%

Next earnings: July 29, 2026 (17 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan7.1%62.5%8
Feb3.4%25.0%8
Mar-2.3%50.0%8
Apr-2.3%37.5%8
May11.8%62.5%8
Jun9.1%75.0%8
Jul5.1%71.4%7
Aug8.3%57.1%7
Sep-6.6%28.6%7
Oct3.0%28.6%7
Nov13.0%75.0%8
Dec-6.6%50.0%8

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.17% 48.9% 366
Tuesday 0.17% 50.1% 401
Wednesday 0.39% 49.0% 398
Thursday 0.40% 51.3% 390
Friday 0.07% 49.2% 390

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 106.0%

Insider Transactions — Smart Summary

Total insider ownership: 4.0%

Founder-led management: Helmy Eltoukhy (Co-Chief Executive Officer and Chairman), AmirAli Talasaz (Co-Chief Executive Officer and Director)

12-Month Insider Activity Summary

Total Filings54
Net Value-$148M
Net Shares Change-1,039,436
% of Float-0.8%
C-Suite Filings27
Clusters Detected9

Key Insiders

NameTitleNet ValueFilingsActivity
Eltoukhy Helmy Co-Chief Executive Officer -$12.6M 1 1 sell
Chudova Darya Chief Technology Officer -$2.4M 1 2 sell
Freeman Chris Chief Commercial Officer -$2.1M 1 1 sell
Krognes Steve E. -$1.2M 1 1 sell
Kalia Kumud Chief Information Officer -$1.2M 3 1 buy, 3 sell
CLARK IAN T -$735,048.526 1 1 sell
Bell Michael Brian Chief Financial Officer -$257,240.6 1 1 sell
Hidalgo Medina Manuel -$130,060.1 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-20 – 2025-09-03 4 4 -$138,474.84 1 C-suite
2025-09-11 – 2025-09-17 4 4 -$18.0M 1 C-suite
2025-11-10 – 2025-11-20 3 3 -$987,260.2 1 C-suite
2025-12-02 – 2025-12-10 8 8 -$29.8M 6 C-suite
2025-12-17 – 2025-12-18 3 3 -$10.0M 2 C-suite
2026-03-05 – 2026-03-19 4 4 -$3.2M 2 C-suite
2026-05-13 – 2026-05-26 7 6 -$33.2M 4 C-suite
2026-05-28 – 2026-06-08 6 6 -$16.4M 3 C-suite
2026-06-12 – 2026-06-23 5 3 -$1.6M 2 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-06-30 Kalia Kumud Chief Information Officer -$78,708 Transaction at $130.87, now +22.3%
2026-06-12 Kalia Kumud Chief Information Officer -$652,030 Transaction at $130.41, now +22.7%
2026-06-15 Kalia Kumud Chief Information Officer -$445,155.535 Transaction at $130.24, now +22.9%
2026-06-08 Eltoukhy Helmy Co-Chief Executive Officer -$12.6M Transaction at $126.30, now +26.7%
2026-06-08 Bell Michael Brian Chief Financial Officer -$257,240.6 Transaction at $128.62, now +24.4%
2026-06-05 Krognes Steve E. -$1.2M Transaction at $132.51, now +20.8%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Guardant Health Inc (GH) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for GH on Trend Edge →