Stock analysis, trade plans, and proprietary indicators by Trend Edge.
About Opko Health Inc
OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical tria… Read full Trend Edge analysis →
Sector: Healthcare
Industry: Diagnostics & Research
Exchange: NASDAQ
IPO Date: November 2, 1995
Headquarters: 4400 Biscayne Boulevard, Miami, FL, United States, 33137
Founder-Led: Yes — Phillip Frost (Chief Executive Officer and Chairman)
Key Metrics
Current Price
$1.30
Market Cap
$967M
Float
332.8M
Shares Outstanding
755.1M
P/E (Forward)
53.76
Price/Sales (TTM)
1.66
vs. Analyst Target
+189.2% to analyst PT
Profit Margin
-36.64%
Operating Margin (TTM)
-41.08%
Revenue (TTM)
$581M
Earnings Growth (YoY)
-12.60%
Dividend Rate
None
Analyst Target Price
$3.76 (7 analysts)
Financial History
Annual Revenue & Earnings History
Year
Revenue
Net Income
Gross Profit
EBITDA
2020
$1.44B
$30.6M
$541M
$156M
2021
$1.77B
-$30.1M
$582M
$83.6M
2022
$1.00B
-$328M
$288M
-$271M
2023
$863M
-$189M
$318M
-$65.5M
2024
$713M
-$53.2M
$311M
$135M
2025
$607M
-$226M
$128M
-$127M
Recent Quarterly Revenue & Net Income
Quarter
Revenue
Net Income
Jun 2025
$157M
-$148M
Sep 2025
$152M
$21.6M
Dec 2025
$148M
-$31.3M
Mar 2026
$124M
-$54.8M
Ownership & Float
Insider Ownership
49.5%
Institutional Ownership
27.2%
Short Float
10.1%
% of All Funds Holding
2.63%
Number of Funds Holding
216
Current Moving Averages
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
Timeframe
SMA
Value
Trend Context
Weekly
10-Week SMA
$1.18
Near-term / short-term trend
Weekly
40-Week SMA
$1.29
Medium-term trend
Weekly
80-Week SMA
$1.38
Cyclical trend (business cycle)
Weekly
200-Week SMA
$1.45
Secular trend (multi-year)
Monthly
10-Month SMA
$1.29
Near-term monthly trend
Monthly
20-Month SMA
$1.39
Medium-term monthly trend
Monthly
40-Month SMA
$1.41
Secular monthly trend
Volume Shelves — Support & Resistance
Trend Edge identifies volume shelves: price zones where historically elevated trading volume
creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative
volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
Price Level
Type
Volume Ratio
Age
$1.00
support
1.91x
25 months ago
Historical Earnings Reactions (110 events)
Timeframe
Avg Return
Median
Win Rate
Best
Worst
Gap
-0.79%
0.00%
38.18%
10.24%
-16.04%
1 Day
-0.10%
-0.14%
40.00%
40.00%
-16.67%
1 Week
1.38%
0.00%
49.09%
54.97%
-24.50%
2 Weeks
-1.27%
0.00%
46.36%
36.76%
-51.52%
1 Month
-0.41%
-0.36%
44.04%
62.86%
-43.98%
Next earnings: July 17, 2026 (49 days away)
Seasonality & Day-of-Week Patterns
Monthly Seasonality
Month
Avg Return
Win Rate
Samples
Jan
7.2%
58.1%
31
Feb
2.8%
45.2%
31
Mar
-0.5%
35.5%
31
Apr
0.5%
38.7%
31
May
0.1%
46.7%
30
Jun
3.7%
46.7%
30
Jul
1.6%
46.7%
30
Aug
6.6%
60.0%
30
Sep
1.0%
33.3%
30
Oct
-1.6%
46.7%
30
Nov
-1.6%
56.7%
30
Dec
0.6%
38.7%
31
Day-of-Week Tendencies
Day
Avg Return
Win Rate
Samples
Monday
0.10%
43.3%
1445
Tuesday
-0.13%
40.1%
1580
Wednesday
-0.07%
41.1%
1577
Thursday
0.29%
42.7%
1545
Friday
0.37%
43.2%
1541
Top Institutional Holders
Institutional holder breakdown coming soon.
Total institutional ownership: 27.2%
Insider Transactions — Smart Summary
Total insider ownership: 49.5%
Founder-led management: Phillip Frost (Chief Executive Officer and Chairman)
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