PLSE — Pulse Biosciences Inc

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates PLSE Bullish with a Setup Score of 0, net conviction 54, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBullish
Net Conviction54
Actionability0 (extended)

Key signals behind this score

About Pulse Biosciences Inc

Pulse Biosciences, Inc. operates as a novel bioelectric medicine company. It offers nPulse System, a novel Nanosecond Pulsed-Field Ablation delivery platform to treat benign lesions of the skin; nPulse Vybrance Percutaneous Electrode system for soft tissue ablation in surgical setting; nPulse Cardiac Surgical Clamp designed for use in surgical treatment of atrial fibrillation (AF); nPulse Cardiac Catheter System designed to provide a circumferent… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$49.13
Market Cap$3.41B
Float20.6M
Shares Outstanding71.3M
Price/Sales (TTM)2,879.99
vs. Analyst Target-7.9% to analyst PT
Operating Margin (TTM)-5823.04%
Revenue (TTM)$1.2M
Dividend RateNone
Analyst Target Price$45.25

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $114,000 -$49.7M -$1.1M -$48.9M
2021 $1.4M -$63.2M -$550,000 -$61.9M
2022 $700,000 -$59.0M -$11.2M -$56.7M
2023 -$9,000 -$42.2M -$1.2M -$39.9M
2024 N/A -$53.6M -$1.2M -$52.4M
2025 $350,000 -$72.8M -$1.3M -$71.7M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $86,000 -$19.4M
Dec 2025 $264,000 -$17.4M
Mar 2026 $401,000 -$18.6M
Jun 2026 $434,000 -$24.7M

Ownership & Float

Insider Ownership71.0%
Institutional Ownership15.4%
Short Float14.5%
% of All Funds Holding1.22%
Number of Funds Holding107

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$36.45Near-term / short-term trend
Weekly40-Week SMA$23.79Medium-term trend
Weekly80-Week SMA$20.11Cyclical trend (business cycle)
Weekly200-Week SMA$13.80Secular trend (multi-year)
Monthly10-Month SMA$23.97Near-term monthly trend
Monthly20-Month SMA$20.48Medium-term monthly trend
Monthly40-Month SMA$15.76Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$27.80 support 1.28x 0 months ago
$36.00 support 1.10x 0 months ago
$18.00 support 1.22x 4 months ago
$13.80 support 2.55x 5 months ago
$11.00 support 1.41x 24 months ago

Historical Earnings Reactions (41 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.56% 0.00% 48.78% 12.57% -16.67%
1 Day 0.96% -0.46% 48.78% 35.48% -28.84%
1 Week 1.13% -1.54% 43.90% 53.63% -26.13%
2 Weeks 4.84% -0.36% 48.78% 134.27% -35.19%
1 Month 8.15% 3.83% 52.50% 243.15% -52.06%

Next earnings: October 25, 2026 (61 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.9%70.0%10
Feb2.8%40.0%10
Mar1.9%40.0%10
Apr10.9%50.0%10
May1.9%40.0%10
Jun1.6%54.5%11
Jul3.6%54.5%11
Aug0.2%60.0%10
Sep12.6%50.0%10
Oct0.8%30.0%10
Nov10.8%50.0%10
Dec8.8%60.0%10

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.22% 44.9% 481
Tuesday 0.20% 46.7% 531
Wednesday 0.04% 48.1% 528
Thursday 0.40% 49.6% 520
Friday 0.42% 49.9% 519

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 15.4%

Insider Transactions — Smart Summary

Total insider ownership: 71.0%

Founder-led management: Darrin R. Uecker (CTO & Director)

12-Month Insider Activity Summary

Total Filings10
Net Value-$3.6M
Net Shares Change1,029,366
% of Float5.0%
C-Suite Filings8
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
DUGGAN ROBERT W +$15.8M 2 2 buy
Danahy Kevin Patrick Chief Commercial Officer -$3.2M 5 N/A
UECKER DARRIN Chief Technology Officer -$726,817 2 N/A
LAVIOLETTE PAUL A Chief Executive Officer +$295,350 1 1 buy

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-09-12 – 2025-09-22 4 3 +$1.7M 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-05-11 LAVIOLETTE PAUL A Chief Executive Officer +$295,350 Transaction at $19.69, now +149.5%
2026-05-15 DUGGAN ROBERT W +$13.0M Transaction at $19.69, now +149.5%
2025-09-12 DUGGAN ROBERT W +$2.8M Transaction at $14.48, now +239.3%
2025-09-18 UECKER DARRIN Chief Technology Officer +$94,935.5 Transaction at $10.12, now +385.3%
2026-02-17 Danahy Kevin Patrick Chief Commercial Officer -$1.3M Transaction at $12.52, now +292.4%
2026-02-11 Danahy Kevin Patrick Chief Commercial Officer -$1.3M Transaction at $12.46, now +294.3%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Pulse Biosciences Inc (PLSE) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for PLSE on Trend Edge →