Stock analysis, trade plans, and proprietary indicators by Trend Edge.
Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; Tissue… Read full Trend Edge analysis →
| Current Price | $22.11 |
|---|---|
| Market Cap | $608M |
| Float | 26.9M |
| Shares Outstanding | 30.3M |
| Price/Sales (TTM) | 1.79 |
| vs. Analyst Target | +107.5% to analyst PT |
| Profit Margin | -3.78% |
| Operating Margin (TTM) | -22.00% |
| Revenue (TTM) | $340M |
| Earnings Growth (YoY) | -51.60% |
| Dividend Rate | None |
| Analyst Target Price | $45.88 (9 analysts) |
| Year | Revenue | Net Income | Gross Profit | EBITDA |
|---|---|---|---|---|
| 2020 | $62.6M | -$10.3M | $53.0M | -$7.1M |
| 2021 | $94.1M | -$31.3M | $78.3M | -$36.6M |
| 2022 | $137M | -$67.1M | $105M | -$58.3M |
| 2023 | $220M | -$57.5M | $175M | -$45.0M |
| 2024 | $332M | $18.2M | $272M | $38.1M |
| 2025 | $344M | -$24.2M | $273M | $11.3M |
| Quarter | Revenue | Net Income |
|---|---|---|
| Jun 2025 | $86.2M | $4.5M |
| Sep 2025 | $83.0M | -$501,000 |
| Dec 2025 | $87.0M | -$2.3M |
| Mar 2026 | $83.7M | -$14.5M |
| Insider Ownership | 2.4% |
|---|---|
| Institutional Ownership | 93.0% |
| Short Float | 5.3% |
| % of All Funds Holding | 2.04% |
| Number of Funds Holding | 168 |
Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.
| Timeframe | SMA | Value | Trend Context |
|---|---|---|---|
| Weekly | 10-Week SMA | $22.70 | Near-term / short-term trend |
| Weekly | 40-Week SMA | $29.09 | Medium-term trend |
| Weekly | 80-Week SMA | $25.59 | Cyclical trend (business cycle) |
| Weekly | 200-Week SMA | $23.87 | Secular trend (multi-year) |
| Monthly | 10-Month SMA | $29.12 | Near-term monthly trend |
| Monthly | 20-Month SMA | $26.22 | Medium-term monthly trend |
| Monthly | 40-Month SMA | $23.89 | Secular monthly trend |
Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.
| Price Level | Type | Volume Ratio | Age |
|---|---|---|---|
| $15.20 | support | 1.63x | 8 months ago |
| Timeframe | Avg Return | Median | Win Rate | Best | Worst |
|---|---|---|---|---|---|
| Gap | 2.80% | 1.12% | 67.86% | 29.57% | -13.55% |
| 1 Day | 2.30% | 0.81% | 60.71% | 32.83% | -22.26% |
| 1 Week | 1.80% | 3.70% | 60.71% | 34.55% | -23.72% |
| 2 Weeks | 1.23% | 2.71% | 57.14% | 29.90% | -27.65% |
| 1 Month | 6.98% | 5.86% | 70.37% | 53.79% | -35.75% |
Next earnings: July 25, 2026 (57 days away)
Insufficient historical data for monthly seasonality analysis (requires 7+ years of data).
| Day | Avg Return | Win Rate | Samples |
|---|---|---|---|
| Monday | -0.01% | 53.0% | 321 |
| Tuesday | 0.49% | 50.8% | 356 |
| Wednesday | -0.18% | 48.4% | 351 |
| Thursday | -0.08% | 47.1% | 344 |
| Friday | 0.29% | 47.5% | 345 |
Institutional holder breakdown coming soon.
Total institutional ownership: 93.0%
Total insider ownership: 2.4%
Founder-led management: Derek Maetzold (Founder, President and CEO)
| Total Filings | 41 |
|---|---|
| Net Value | -$11.6M |
| Net Shares Change | -398,047 |
| % of Float | -1.5% |
| C-Suite Filings | 40 |
| Clusters Detected | 3 |
| Name | Title | Net Value | Filings | Activity |
|---|---|---|---|---|
| MAETZOLD DEREK J | Pres. and Chief Exec. Officer | -$1.9M | 2 | N/A |
| Oelschlager Kristen M | Chief Operating Officer | -$1.6M | 3 | 3 sell |
| Juvenal Tobin W | Chief Commercial Officer | -$1.0M | 2 | 1 sell |
| Stokes Frank | Chief Financial Officer | -$336,283.18 | 2 | 1 sell |
| Cole G Bradley | -$194,678.895 | 1 | 1 sell |
| Period | Filings | Insiders | Net Value | Seniority |
|---|---|---|---|---|
| 2025-11-13 – 2025-11-26 | 7 | 4 | -$1.3M | 7 C-suite |
| 2025-12-01 – 2025-12-15 | 5 | 3 | -$992,472.53 | 5 C-suite |
| 2026-03-09 – 2026-03-19 | 6 | 4 | -$3.3M | 5 C-suite |
| Date | Insider | Title | Net Value | Price After |
|---|---|---|---|---|
| 2026-03-09 | Cole G Bradley | -$194,678.895 | Transaction at $15.92, now +38.9% | |
| 2025-12-15 | Juvenal Tobin W | Chief Commercial Officer | -$494,736 | Transaction at $37.48, now -41.0% |
| 2025-12-19 | Oelschlager Kristen M | Chief Operating Officer | -$585,291.944 | Transaction at $39.31, now -43.8% |
| 2025-12-15 | Stokes Frank | Chief Financial Officer | -$168,375.2 | Transaction at $37.45, now -41.0% |
| 2025-08-29 | Oelschlager Kristen M | Chief Operating Officer | -$669,706.693 | Transaction at $21.85, now +1.2% |
| 2026-03-16 | Juvenal Tobin W | Chief Commercial Officer | -$526,582.12 | Transaction at $25.24, now -12.4% |
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AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.
Get the full AI Consult analysis for CSTL on Trend Edge →