UTHR — United Therapeutics Corporation

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates UTHR Bullish with a Setup Score of 0, net conviction 56, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBullish
Net Conviction56
Actionability0 (in range)

Key signals behind this score

About United Therapeutics Corporation

United Therapeutics Corporation engages in the development and commercialization of products to address the unmet medical needs of patients with chronic and life-threatening diseases in the United States and internationally. It offers Tyvaso DPI, an inhaled dry powder via pre-filled and single-use cartridges; Nebulized Tyvaso, an inhaled solution via ultrasonic nebulizer; Remodulin (treprostinil) injection to treat patients with pulmonary arteria… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$547.06
Market Cap$23.45B
Float38.9M
Shares Outstanding42.4M
P/E (Forward)20.16
P/E (TTM)20.42
Price/Sales (TTM)7.40
vs. Analyst Target+21.6% to analyst PT
Profit Margin40.62%
Operating Margin (TTM)41.69%
Revenue (TTM)$3.17B
Earnings Growth (YoY)-12.20%
Dividend RateNone
Analyst Target Price$665.46 (15 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $1.48B $515M $1.38B $646M
2021 $1.69B $476M $1.56B $737M
2022 $1.94B $727M $1.79B $1.04B
2023 $2.33B $985M $2.07B $1.39B
2024 $2.88B $1.20B $2.57B $1.65B
2025 $3.18B $1.33B $2.80B $1.82B

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $799M $310M
Sep 2025 $800M $339M
Dec 2025 $790M $364M
Mar 2026 $782M $275M

Ownership & Float

Insider Ownership2.0%
Institutional Ownership102.1%
Short Float5.3%
% of All Funds Holding9.70%
Number of Funds Holding797

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$553.68Near-term / short-term trend
Weekly40-Week SMA$510.04Medium-term trend
Weekly80-Week SMA$419.12Cyclical trend (business cycle)
Weekly200-Week SMA$325.74Secular trend (multi-year)
Monthly10-Month SMA$520.21Near-term monthly trend
Monthly20-Month SMA$422.12Medium-term monthly trend
Monthly40-Month SMA$343.91Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$510.00 support 1.22x 3 months ago
$422.00 support 1.22x 8 months ago
$285.00 support 1.62x 10 months ago
$243.00 support 1.51x 25 months ago

Historical Earnings Reactions (108 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.07% 0.09% 53.70% 3.21% -7.00%
1 Day 0.51% 0.64% 63.89% 9.29% -8.50%
1 Week 0.81% 0.00% 50.00% 26.82% -11.53%
2 Weeks 0.47% 0.12% 50.00% 41.05% -30.93%
1 Month 1.41% 1.19% 55.14% 76.84% -76.04%

Next earnings: July 29, 2026 (17 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan0.5%44.4%27
Feb2.2%51.9%27
Mar1.4%48.1%27
Apr-2.2%40.7%27
May4.7%55.6%27
Jun2.7%51.9%27
Jul4.4%59.3%27
Aug5.2%51.9%27
Sep1.6%44.4%27
Oct-0.3%63.0%27
Nov5.6%63.0%27
Dec3.0%59.3%27

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.08% 49.2% 1277
Tuesday 0.18% 51.6% 1396
Wednesday 0.07% 51.6% 1396
Thursday 0.17% 50.4% 1369
Friday 0.21% 51.1% 1364

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 102.1%

Insider Transactions — Smart Summary

Total insider ownership: 2.0%

Founder-led management: Martine Rothblatt (Founder, Chairman & CEO)

12-Month Insider Activity Summary

Total Filings236
Net Value-$892M
Net Shares Change-87,007
% of Float-0.2%
C-Suite Filings203
Clusters Detected19

Key Insiders

NameTitleNet ValueFilingsActivity
Thompson Tommy G -$2.0M 3 3 sell
KURZWEIL RAY -$1.9M 1 1 sell
SULLIVAN LOUIS W -$1.8M 1 1 sell
Olian Judy D. -$747,767.88 1 1 sell
PATUSKY CHRISTOPHER -$394,153.9 1 1 sell
Mesa Nilda -$240,204.059 2 2 sell
MALCOLM JAN -$178,941.75 1 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-09-02 – 2025-09-16 9 6 -$18.9M 6 C-suite
2025-09-17 – 2025-10-01 12 5 -$35.6M 10 C-suite
2025-10-02 – 2025-10-16 9 3 -$32.5M 9 C-suite
2025-10-20 – 2025-10-30 8 3 -$31.7M 8 C-suite
2025-11-04 – 2025-11-18 13 4 -$64.9M 13 C-suite
2025-11-20 – 2025-12-02 10 4 -$47.6M 10 C-suite
2025-12-05 – 2025-12-19 15 8 -$42.2M 11 C-suite
2025-12-23 – 2026-01-06 9 5 -$33.5M 4 C-suite
2026-01-07 – 2026-01-20 4 3 -$18.7M 3 C-suite
2026-01-28 – 2026-02-10 5 3 -$37.1M 4 C-suite
2026-02-17 – 2026-03-03 8 6 -$19.7M 4 C-suite
2026-03-05 – 2026-03-19 16 7 -$67.0M 10 C-suite
2026-03-20 – 2026-04-02 16 6 -$55.7M 13 C-suite
2026-04-06 – 2026-04-20 17 4 -$70.5M 16 C-suite
2026-04-21 – 2026-05-05 17 3 -$67.8M 16 C-suite
2026-05-06 – 2026-05-20 16 4 -$66.2M 15 C-suite
2026-05-21 – 2026-06-04 15 3 -$56.7M 15 C-suite
2026-06-05 – 2026-06-18 15 3 -$58.7M 15 C-suite
2026-06-22 – 2026-07-02 13 3 -$53.4M 13 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-05-13 Mesa Nilda -$150,139.23 Transaction at $581.93, now -6.0%
2026-07-10 MALCOLM JAN -$178,941.75 Transaction at $550.59, now -0.6%
2026-03-05 KURZWEIL RAY -$1.9M Transaction at $295.41, now +85.2%
2026-03-26 Thompson Tommy G -$874,732.2 Transaction at $320.48, now +70.7%
2026-03-05 Thompson Tommy G -$775,239.4 Transaction at $295.61, now +85.1%
2025-09-19 Olian Judy D. -$747,767.88 Transaction at $415.43, now +31.7%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for United Therapeutics Corporation (UTHR) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for UTHR on Trend Edge →