KNSA — Kiniksa Pharmaceuticals Ltd

Founder-Led

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Kiniksa Pharmaceuticals Ltd

Kiniksa Pharmaceuticals International, plc, a biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally. The company offers ARCALYST, an interleukin-1alpha and 1beta cytokine trap for the treatment of recurrent pericarditis, a chronic autoinflammatory cardiovascular disease and cardiac sarcoidosis. Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$51.84
Market Cap$4.18B
Float40.3M
Shares Outstanding46.3M
P/E (Forward)48.54
P/E (TTM)59.65
Price/Sales (TTM)5.54
vs. Analyst Target+22.5% to analyst PT
Profit Margin9.69%
Operating Margin (TTM)13.66%
Revenue (TTM)$754M
Earnings Growth (YoY)145.50%
Dividend RateNone
Analyst Target Price$63.50 (6 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $7.7M -$161M -$3.8M -$155M
2021 $38.5M -$158M $29.4M -$154M
2022 $220M $183M $197M $12.2M
2023 $270M $14.1M $214M -$22.9M
2024 $423M -$43.2M $362M -$43.9M
2025 $678M $59.0M $370M $90.4M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $157M $17.8M
Sep 2025 $181M $18.4M
Dec 2025 $202M $14.2M
Mar 2026 $214M $22.6M

Ownership & Float

Insider Ownership3.6%
Institutional Ownership101.8%
Short Float8.8%
% of All Funds Holding2.49%
Number of Funds Holding205

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$50.48Near-term / short-term trend
Weekly40-Week SMA$43.35Medium-term trend
Weekly80-Week SMA$33.77Cyclical trend (business cycle)
Weekly200-Week SMA$23.82Secular trend (multi-year)
Monthly10-Month SMA$43.53Near-term monthly trend
Monthly20-Month SMA$33.70Medium-term monthly trend
Monthly40-Month SMA$25.80Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$49.00 support 1.50x 0 months ago
$45.00 support 1.18x 1 months ago
$27.60 support 1.20x 9 months ago
$22.10 support 1.51x 12 months ago
$18.50 support 1.55x 21 months ago

Historical Earnings Reactions (32 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.64% 0.35% 62.50% 9.19% -2.64%
1 Day 1.01% -0.32% 50.00% 19.01% -6.28%
1 Week 2.57% 0.90% 56.25% 17.74% -23.24%
2 Weeks 0.79% 0.63% 53.13% 23.83% -20.28%
1 Month 7.21% 4.15% 61.29% 94.38% -19.39%

Next earnings: July 17, 2026 (50 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan0.6%50.0%8
Feb4.7%75.0%8
Mar-4.2%37.5%8
Apr2.8%37.5%8
May0.5%71.4%7
Jun5.2%75.0%8
Jul5.3%62.5%8
Aug3.2%50.0%8
Sep1.1%50.0%8
Oct-10.8%12.5%8
Nov19.3%87.5%8
Dec2.9%50.0%8

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.07% 52.5% 377
Tuesday 0.52% 51.3% 415
Wednesday 0.04% 49.0% 410
Thursday -0.23% 45.2% 403
Friday 0.22% 52.2% 404

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 101.8%

Insider Transactions — Smart Summary

Total insider ownership: 3.6%

Founder-led management: Sanj K. Patel (CEO & Chairman of the Board), Eben P. Tessari (Chief Strategy Officer), Aaron Isadore Young (Chief Intellectual Property Officer)

12-Month Insider Activity Summary

Total Filings46
Net Value-$58.1M
Net Shares Change-87,642
% of Float-0.2%
C-Suite Filings39
Clusters Detected7

Key Insiders

NameTitleNet ValueFilingsActivity
Malley Thomas -$4.0M 1 1 sell
Megna Michael R CHIEF ACCOUNTING OFFICER -$1.8M 2 N/A
Tessari Eben CHIEF OPERATING OFFICER -$1.3M 3 N/A
Ragosa Mark CHIEF FINANCIAL OFFICER -$1.1M 2 N/A
Quart Barry D -$728,697.738 1 1 sell
Moat Ross CHIEF OPERATING OFFICER -$79,513.07 1 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-05-28 – 2025-06-11 6 6 -$5.2M 5 C-suite
2025-08-06 – 2025-08-20 6 5 -$8.9M 5 C-suite
2025-09-03 – 2025-09-17 5 3 -$3.4M 5 C-suite
2025-10-16 – 2025-10-30 4 4 -$11.0M 4 C-suite
2025-12-10 – 2025-12-17 3 3 -$2.4M 2 C-suite
2026-04-08 – 2026-04-13 5 4 -$1.3M 4 C-suite
2026-04-29 – 2026-05-05 4 3 -$23.7M 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-04-13 Moat Ross CHIEF OPERATING OFFICER -$79,513.07 Transaction at $46.69, now +11.0%
2026-04-13 Megna Michael R CHIEF ACCOUNTING OFFICER -$309,321.25 Transaction at $46.69, now +11.0%
2025-08-14 Malley Thomas -$4.0M Transaction at $21.59, now +140.1%
2025-06-11 Quart Barry D -$728,697.738 Transaction at $17.07, now +203.6%
2026-02-11 Ragosa Mark CHIEF FINANCIAL OFFICER -$621,884.604 Transaction at $28.57, now +81.4%
2026-01-09 Ragosa Mark CHIEF FINANCIAL OFFICER -$502,680 Transaction at $41.89, now +23.8%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Kiniksa Pharmaceuticals Ltd (KNSA) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for KNSA on Trend Edge →