IRWD — Ironwood Pharmaceuticals Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Ironwood Pharmaceuticals Inc

Ironwood Pharmaceuticals, Inc., a biotechnology company, focuses on the development and commercialization of therapies for gastrointestinal (GI) and rare diseases in the United States and internationally. It sells linaclotide, a guanylate cyclase type-C (GC-C) agonist for the treatment of adults suffering from irritable bowel syndrome with constipation or chronic idiopathic constipation, as well as for pediatric patients suffering from functional… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$3.90
Market Cap$645M
Float136.3M
Shares Outstanding164.6M
P/E (Forward)12.33
P/E (TTM)6.32
Price/Sales (TTM)1.75
vs. Analyst Target+56.4% to analyst PT
Profit Margin28.26%
Operating Margin (TTM)68.10%
Revenue (TTM)$362M
Earnings Growth (YoY)1046.80%
Dividend RateNone
Analyst Target Price$6.10 (4 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $390M $106M $386M $142M
2021 $414M $528M $343M $234M
2022 $411M $175M $409M $261M
2023 $443M -$1.00B $437M $197M
2024 $351M $880,000 $344M $97.7M
2025 $296M $24.0M $296M $105M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $85.2M $23.6M
Sep 2025 $122M $40.1M
Dec 2025 $47.7M -$2.3M
Mar 2026 $107M $40.8M

Ownership & Float

Insider Ownership2.9%
Institutional Ownership98.2%
Short Float12.7%
% of All Funds Holding2.47%
Number of Funds Holding203

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$3.86Near-term / short-term trend
Weekly40-Week SMA$3.19Medium-term trend
Weekly80-Week SMA$2.48Cyclical trend (business cycle)
Weekly200-Week SMA$6.68Secular trend (multi-year)
Monthly10-Month SMA$3.13Near-term monthly trend
Monthly20-Month SMA$2.58Medium-term monthly trend
Monthly40-Month SMA$5.85Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$4.80 resistance 1.16x 2 months ago
$2.00 support 1.35x 5 months ago

Historical Earnings Reactions (66 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.10% 0.00% 46.97% 10.16% -9.74%
1 Day 0.49% 0.32% 53.03% 14.23% -9.36%
1 Week 0.04% -0.59% 48.48% 31.99% -14.15%
2 Weeks 0.51% -0.36% 46.97% 44.32% -26.18%
1 Month 0.11% -0.74% 44.62% 41.50% -29.21%

Next earnings: July 26, 2026 (60 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.9%50.0%16
Feb-4.1%37.5%16
Mar2.9%58.8%17
Apr-4.0%23.5%17
May-1.6%50.0%16
Jun2.7%81.3%16
Jul-0.0%43.8%16
Aug-3.1%18.8%16
Sep-1.6%37.5%16
Oct2.5%50.0%16
Nov9.9%62.5%16
Dec1.3%50.0%16

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.01% 47.7% 767
Tuesday 0.10% 47.3% 843
Wednesday 0.02% 48.8% 840
Thursday -0.09% 48.7% 826
Friday 0.17% 50.6% 824

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 98.2%

Insider Transactions — Smart Summary

Total insider ownership: 2.9%

12-Month Insider Activity Summary

Total Filings13
Net Value-$1.3M
Net Shares Change-7,081,938
% of Float-5.2%
C-Suite Filings12
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
DENNER ALEXANDER J -$20.5M 1 1 sell
MCCOURT Thomas A Chief Executive Officer -$739,932.671 1 N/A
Silver Ronald Principal Accounting Officer -$255,510.624 3 N/A
John Minardo Chief Legal Officer -$136,177.196 1 N/A
Gaskins Tammi L Chief Commercial Officer -$100,301.694 2 N/A
Martini Gregory S. Chief Financial Officer -$81,888.425 1 N/A
Shetzline Michael SVP, CMO, Head-ResandDrug +$2,942.22 1 N/A

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-08-13 – 2025-08-13 4 4 -$11,072.04 4 C-suite
2026-02-25 – 2026-02-25 6 6 -$1.1M 6 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-03-17 DENNER ALEXANDER J -$20.5M Transaction at $3.05, now +27.9%
2026-02-25 Martini Gregory S. Chief Financial Officer -$81,888.425 Transaction at $3.73, now +4.5%
2026-02-25 MCCOURT Thomas A Chief Executive Officer -$739,932.671 Transaction at $3.73, now +4.5%
2026-01-07 Silver Ronald Principal Accounting Officer -$162,913.6 Transaction at $4.60, now -15.2%
2026-02-25 Silver Ronald Principal Accounting Officer -$90,206.384 Transaction at $3.73, now +4.5%
2026-02-25 John Minardo Chief Legal Officer -$136,177.196 Transaction at $3.73, now +4.5%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Ironwood Pharmaceuticals Inc (IRWD) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for IRWD on Trend Edge →