ESPR — Esperion Therapeutics Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

About Esperion Therapeutics Inc

Esperion Therapeutics, Inc., a biopharmaceutical company, develops and commercializes medicines for the treatment of patients with elevated low density lipoprotein cholesterol (LDL-C) in the United States. The company's marketed products include NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) tablets that are oral, once-daily, non-statin medicines for the treatment of primary hyperlipidemia in adults with heterozygous famili… Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$3.12
Market Cap$806M
Float255.2M
Shares Outstanding257.4M
P/E (Forward)4.64
Price/Sales (TTM)1.93
vs. Analyst Target+2.2% to analyst PT
Profit Margin-1.78%
Operating Margin (TTM)-8.22%
Revenue (TTM)$418M
Dividend RateNone
Analyst Target Price$3.19 (7 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $228M -$144M $225M -$120M
2021 $78.4M -$269M $64.2M -$222M
2022 $75.5M -$234M $48.5M -$176M
2023 $116M -$209M $73.1M -$150M
2024 $332M -$51.7M $264M $7.6M
2025 $403M -$22.7M $274M $60.3M

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $82.4M -$12.7M
Sep 2025 $87.3M -$31.3M
Dec 2025 $168M $61.8M
Mar 2026 $80.1M -$25.2M

Ownership & Float

Insider Ownership0.7%
Institutional Ownership69.8%
Short Float14.3%
% of All Funds Holding2.34%
Number of Funds Holding192

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$2.71Near-term / short-term trend
Weekly40-Week SMA$3.03Medium-term trend
Weekly80-Week SMA$2.33Cyclical trend (business cycle)
Weekly200-Week SMA$2.83Secular trend (multi-year)
Monthly10-Month SMA$3.02Near-term monthly trend
Monthly20-Month SMA$2.32Medium-term monthly trend
Monthly40-Month SMA$2.17Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$1.40 support 1.03x 8 months ago
$1.00 support 1.05x 9 months ago

Historical Earnings Reactions (52 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap -0.71% 0.02% 50.00% 16.66% -28.14%
1 Day -0.78% -0.04% 50.00% 18.52% -21.81%
1 Week 0.24% -1.06% 40.38% 30.18% -28.33%
2 Weeks 2.32% -1.09% 47.06% 77.85% -34.17%
1 Month 5.08% -2.11% 47.06% 69.86% -39.71%

Next earnings: May 12, 2026

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan-4.3%46.2%13
Feb11.4%46.2%13
Mar-4.0%46.2%13
Apr-4.7%38.5%13
May-3.2%66.7%12
Jun3.4%75.0%12
Jul-0.1%46.2%13
Aug2.7%46.2%13
Sep-0.1%53.8%13
Oct-1.7%53.8%13
Nov14.8%69.2%13
Dec6.7%46.2%13

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday 0.40% 49.6% 609
Tuesday 0.23% 49.2% 669
Wednesday -0.08% 49.8% 664
Thursday -0.36% 47.2% 652
Friday 0.32% 52.3% 652

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 69.8%

Insider Transactions — Smart Summary

Total insider ownership: 0.7%

12-Month Insider Activity Summary

Total Filings16
Net Value-$506,113.933
Net Shares Change-189,925
% of Float-0.1%
C-Suite Filings16
Clusters Detected4

Key Insiders

NameTitleNet ValueFilingsActivity
Koenig Sheldon L. President and CEO -$326,001.27 3 3 sell
Looker Benjamin Chief Legal Officer -$65,042.305 5 5 sell
Halladay Benjamin Chief Financial Officer -$44,281.699 2 2 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-06-18 – 2025-06-18 3 3 -$49,521.618 3 C-suite
2025-09-18 – 2025-09-18 3 3 -$116,612.312 3 C-suite
2025-12-18 – 2025-12-18 3 3 -$228,002.83 3 C-suite
2026-03-18 – 2026-03-18 3 3 -$102,352.226 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-03-18 Looker Benjamin Chief Legal Officer -$15,428.724 Transaction at $2.70, now +15.4%
2026-03-18 Koenig Sheldon L. President and CEO -$69,546.582 Transaction at $2.72, now +14.7%
2026-03-18 Halladay Benjamin Chief Financial Officer -$17,376.92 Transaction at $2.71, now +15.3%
2025-12-18 Koenig Sheldon L. President and CEO -$177,200.212 Transaction at $3.67, now -15.1%
2026-01-21 Looker Benjamin General Counsel -$4,867.698 Transaction at $2.88, now +8.3%
2025-12-18 Looker Benjamin General Counsel -$23,897.839 Transaction at $3.67, now -14.9%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Esperion Therapeutics Inc (ESPR) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for ESPR on Trend Edge →