AMGN — Amgen Inc

✨ Hidden Gem

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates AMGN Bullish with a Setup Score of 0, net conviction 47, actionability 0. How the Setup Score works →

Total Setup Score0
Directional BiasBullish
Net Conviction47
Actionability0 (extended)

Key signals behind this score

About Amgen Inc

Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide. The company's principal products include Enbrel for the treatment of rheumatoid arthritis, plaque psoriasis, and psoriatic arthritis; Otezla for the treatment of adult patients with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease; Prolia to treat postmenopausal women with osteoporosis; XGEVA for skeletal-related events … Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$442.24
Market Cap$234.65B
Float539.2M
Shares Outstanding541.0M
P/E (Forward)19.72
P/E (TTM)27.47
Price/Sales (TTM)6.16
vs. Analyst Target-12.2% to analyst PT
Profit Margin22.95%
Operating Margin (TTM)35.55%
Revenue (TTM)$38.09B
Earnings Growth (YoY)64.90%
Dividend Rate10.1%
Analyst Target Price$388.48 (32 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $25.42B $7.26B $19.27B $13.00B
2021 $25.98B $5.89B $19.52B $11.30B
2022 $26.32B $6.55B $19.92B $12.17B
2023 $28.19B $6.72B $19.74B $7.90B
2024 $33.42B $4.09B $20.57B $13.36B
2025 $36.74B $7.71B $26.01B $16.90B

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Sep 2025 $9.56B $3.22B
Dec 2025 $9.90B $1.33B
Mar 2026 $8.62B $1.82B
Jun 2026 $10.05B $2.38B

Ownership & Float

Insider Ownership0.2%
Institutional Ownership85.1%
Short Float2.5%
% of All Funds Holding35.60%
Number of Funds Holding3,131

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$393.11Near-term / short-term trend
Weekly40-Week SMA$357.73Medium-term trend
Weekly80-Week SMA$326.24Cyclical trend (business cycle)
Weekly200-Week SMA$296.53Secular trend (multi-year)
Monthly10-Month SMA$362.72Near-term monthly trend
Monthly20-Month SMA$327.70Medium-term monthly trend
Monthly40-Month SMA$304.65Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$334.00 support 1.16x 1 months ago
$299.00 support 1.03x 8 months ago
$263.00 support 1.11x 18 months ago

Historical Earnings Reactions (122 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.05% -0.22% 45.08% 12.57% -9.85%
1 Day 0.23% -0.47% 45.08% 13.08% -13.41%
1 Week 0.23% 0.11% 50.82% 21.79% -15.68%
2 Weeks 0.34% -1.07% 45.90% 29.50% -17.28%
1 Month 0.97% -0.32% 48.76% 26.29% -14.15%

Next earnings: October 23, 2026 (58 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.6%65.1%43
Feb0.2%48.8%43
Mar1.7%51.2%43
Apr-0.3%41.9%43
May2.2%51.2%43
Jun0.6%51.2%43
Jul5.3%77.3%44
Aug0.5%60.5%43
Sep0.1%51.2%43
Oct2.2%53.5%43
Nov2.2%60.5%43
Dec4.5%62.8%43

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.00% 46.9% 2055
Tuesday 0.08% 49.2% 2232
Wednesday 0.23% 48.9% 2229
Thursday 0.04% 47.4% 2188
Friday 0.11% 49.3% 2176

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 85.1%

Insider Transactions — Smart Summary

Total insider ownership: 0.2%

12-Month Insider Activity Summary

Total Filings9
Net Value-$18.2M
Net Shares Change-12,248
% of Float-0.0%
C-Suite Filings9
Clusters Detected2

Key Insiders

NameTitleNet ValueFilingsActivity
Santos Esteban EVP, Operations -$11.5M 1 1 sell
Gordon Murdo EVP, Global Commercial Ops -$2.3M 1 1 sell
Grygiel Nancy A. SVP & CCO -$1.7M 3 3 sell
Khosla Rachna SVP, Business Development -$1.4M 2 2 sell
Miller Derek SVP, Human Resources -$906,323.709 1 1 sell
Busch Matthew C. VP, Finance & CAO -$375,790 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-11-13 – 2025-11-20 3 3 -$3.1M 3 C-suite
2026-08-06 – 2026-08-13 3 3 -$2.7M 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-08-13 Khosla Rachna SVP, Business Development -$1.1M Transaction at $288.33, now +53.4%
2026-08-06 Miller Derek SVP, Human Resources -$906,323.709 Transaction at $286.05, now +54.6%
2026-08-06 Grygiel Nancy A. SVP & CCO -$667,509.282 Transaction at $289.78, now +52.6%
2026-05-05 Grygiel Nancy A. SVP & CCO -$480,266.986 Transaction at $326.77, now +35.3%
2026-02-27 Santos Esteban EVP, Operations -$11.5M Transaction at $274.15, now +61.3%
2025-11-14 Gordon Murdo EVP, Global Commercial Ops -$2.3M Transaction at $336.83, now +31.3%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Amgen Inc (AMGN) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for AMGN on Trend Edge →