AMGN — Amgen Inc

Stock analysis, trade plans, and proprietary indicators by Trend Edge.

Trend Edge Setup Score

Trend Edge rates AMGN Bullish with a Setup Score of 36, net conviction 54, actionability 24. How the Setup Score works →

Total Setup Score36
Directional BiasBullish
Net Conviction54
Actionability24 (in range)

Key signals behind this score

About Amgen Inc

Amgen Inc. discovers, develops, manufactures, and delivers human therapeutics worldwide. The company's principal products include Enbrel for the treatment of rheumatoid arthritis, plaque psoriasis, and psoriatic arthritis; Otezla for the treatment of adult patients with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease; Prolia to treat postmenopausal women with osteoporosis; XGEVA for skeletal-related events … Read full Trend Edge analysis →

Trend Edge Proprietary Indicators

Key Metrics

Current Price$363.39
Market Cap$196.25B
Float538.2M
Shares Outstanding539.7M
P/E (Forward)16.53
P/E (TTM)25.64
Price/Sales (TTM)5.27
vs. Analyst Target-2.1% to analyst PT
Profit Margin20.96%
Operating Margin (TTM)33.80%
Revenue (TTM)$37.22B
Earnings Growth (YoY)4.40%
Dividend Rate10.1%
Analyst Target Price$355.66 (32 analysts)

Financial History

Annual Revenue & Earnings History

YearRevenueNet IncomeGross ProfitEBITDA
2020 $25.42B $7.26B $19.27B $13.00B
2021 $25.98B $5.89B $19.52B $11.30B
2022 $26.32B $6.55B $19.92B $12.17B
2023 $28.19B $6.72B $19.74B $7.90B
2024 $33.42B $4.09B $20.57B $13.36B
2025 $36.74B $7.71B $26.01B $16.90B

Recent Quarterly Revenue & Net Income

QuarterRevenueNet Income
Jun 2025 $9.17B $1.43B
Sep 2025 $9.56B $3.22B
Dec 2025 $9.90B $1.33B
Mar 2026 $8.62B $1.82B

Ownership & Float

Insider Ownership0.2%
Institutional Ownership85.1%
Short Float2.3%
% of All Funds Holding35.70%
Number of Funds Holding2,934

Current Moving Averages

Trend Edge tracks near-term, medium-term, cyclical, and secular moving averages across weekly and monthly timeframes to identify trend structure at every horizon.

TimeframeSMAValueTrend Context
Weekly10-Week SMA$347.24Near-term / short-term trend
Weekly40-Week SMA$341.19Medium-term trend
Weekly80-Week SMA$315.07Cyclical trend (business cycle)
Weekly200-Week SMA$290.80Secular trend (multi-year)
Monthly10-Month SMA$346.16Near-term monthly trend
Monthly20-Month SMA$317.53Medium-term monthly trend
Monthly40-Month SMA$299.05Secular monthly trend

Volume Shelves — Support & Resistance

Trend Edge identifies volume shelves: price zones where historically elevated trading volume creates structural support or resistance. A volume shelf forms when a disproportionate share of cumulative volume was transacted at a specific price level, making it a high-conviction anchor for future price reactions.

Price LevelTypeVolume RatioAge
$334.00 support 1.16x 0 months ago
$388.00 resistance 1.10x 3 months ago
$299.00 support 1.03x 7 months ago
$263.00 support 1.11x 17 months ago

Historical Earnings Reactions (121 events)

TimeframeAvg ReturnMedianWin RateBestWorst
Gap 0.05% -0.22% 44.63% 12.57% -9.85%
1 Day 0.19% -0.48% 44.63% 13.08% -13.41%
1 Week 0.18% 0.05% 50.41% 21.79% -15.68%
2 Weeks 0.23% -1.08% 45.45% 29.50% -17.28%
1 Month 0.99% -0.21% 49.17% 26.29% -14.15%

Next earnings: August 4, 2026 (23 days away)

Seasonality & Day-of-Week Patterns

Monthly Seasonality

MonthAvg ReturnWin RateSamples
Jan3.6%65.1%43
Feb0.2%48.8%43
Mar1.7%51.2%43
Apr-0.3%41.9%43
May2.2%51.2%43
Jun0.6%51.2%43
Jul5.3%76.7%43
Aug0.5%60.5%43
Sep0.1%51.2%43
Oct2.2%53.5%43
Nov2.2%60.5%43
Dec4.5%62.8%43

Day-of-Week Tendencies

DayAvg ReturnWin RateSamples
Monday -0.00% 46.9% 2048
Tuesday 0.07% 49.2% 2225
Wednesday 0.23% 48.9% 2222
Thursday 0.04% 47.4% 2181
Friday 0.11% 49.3% 2169

Top Institutional Holders

Institutional holder breakdown coming soon.

Total institutional ownership: 85.1%

Insider Transactions — Smart Summary

Total insider ownership: 0.2%

12-Month Insider Activity Summary

Total Filings7
Net Value-$15.9M
Net Shares Change-11,515
% of Float-0.0%
C-Suite Filings7
Clusters Detected1

Key Insiders

NameTitleNet ValueFilingsActivity
Santos Esteban EVP, Operations -$11.5M 1 1 sell
Gordon Murdo EVP, Global Commercial Ops -$2.3M 1 1 sell
Grygiel Nancy A. SVP & CCO -$1.4M 3 3 sell
Busch Matthew C. VP, Finance & CAO -$375,790 1 1 sell
Khosla Rachna SVP, Business Development -$299,255.558 1 1 sell

Transaction Clusters

PeriodFilingsInsidersNet ValueSeniority
2025-11-13 – 2025-11-20 3 3 -$3.1M 3 C-suite

Significant Filings

DateInsiderTitleNet ValuePrice After
2026-05-05 Grygiel Nancy A. SVP & CCO -$480,266.986 Transaction at $326.77, now +11.2%
2026-02-27 Santos Esteban EVP, Operations -$11.5M Transaction at $274.15, now +32.6%
2026-02-20 Busch Matthew C. VP, Finance & CAO -$375,790 Transaction at $375.79, now -3.3%
2025-11-14 Gordon Murdo EVP, Global Commercial Ops -$2.3M Transaction at $336.83, now +7.9%
2025-08-21 Grygiel Nancy A. SVP & CCO -$376,279.995 Transaction at $296.99, now +22.4%
2025-11-20 Grygiel Nancy A. SVP & CCO -$525,975.549 Transaction at $253.48, now +43.4%

View full insider transaction history on Trend Edge →

AI Consult Analysis

Trend Edge's AI Consult feature delivers a comprehensive, multi-layer trade plan for Amgen Inc (AMGN) powered by Claude Opus — Anthropic's most capable AI model. The analysis covers five layers: technical analysis (near-term, medium-term, cyclical, and secular trend, momentum, volume shelf support and resistance, breakout and breakdown signals), qualitative analysis (business model, competitive moat, sector dynamics), insider sentiment (buy and sell signals from executive and director transactions), share stats analysis (institutional accumulation, fund positioning, short float squeeze potential), and fundamental analysis (valuation, revenue growth, profit margin, earnings quality).

AI Consult synthesizes all five layers into a single bullish or bearish thesis with explicit entry, exit, stop loss, and take profit levels — giving you a complete, AI-powered trade plan with defined risk/reward. Whether you are building a long position, initiating a short, or looking for a reversal setup, AI Consult identifies the highest-probability signal from the current trend.

Get the full AI Consult analysis for AMGN on Trend Edge →